Search Results - "Murray, Amber N."

Impaired Thermosensation in Mice Lacking TRPV3, a Heat and Camphor Sensor in the Skin by Moqrich, Aziz, Hwang, Sun Wook, Earley, Taryn J., Petrus, Matt J., Murray, Amber N., Kathryn S. R. Spencer, Andahazy, Mary, Story, Gina M., Patapoutian, Ardem

“…Environmental temperature is thought to be directly sensed by neurons through their projections in the skin. A subset of the mammalian transient receptor…”
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Hsp104 Gives Clients the Individual Attention They Need by Murray, Amber N., Kelly, Jeffery W.

“…Yeast heat shock protein 104 (Hsp104), the only known eukaryotic disaggregase, remodels both disordered protein aggregates and cross-β sheet amyloids. To…”
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TRPM8 Is Required for Cold Sensation in Mice by Dhaka, Ajay, Murray, Amber N., Mathur, Jayanti, Earley, Taryn J., Petrus, Matt J., Patapoutian, Ardem

“…ThermoTRPs, a subset of the Transient Receptor Potential (TRP) family of cation channels, have been implicated in sensing temperature. TRPM8 and TRPA1 are both…”
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Surface adsorption considerations when working with amyloid fibrils in multiwell plates and Eppendorf tubes by Murray, Amber N., Palhano, Fernando L., Bieschke, Jan, Kelly, Jeffery W.

“…The accumulation of cross‐β‐sheet amyloid fibrils is the hallmark of amyloid diseases. Recently, we reported the discovery of amyloid disaggregase activities…”
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A Kinetic Aggregation Assay Allowing Selective and Sensitive Amyloid-β Quantification in Cells and Tissues by Du, Deguo, Murray, Amber N, Cohen, Ehud, Kim, Hyun-Eui, Simkovsky, Ryan, Dillin, Andrew, Kelly, Jeffery W

“…The process of amyloid-β (Aβ) fibril formation is genetically and pathologically linked to Alzheimer’s disease (AD). Thus, a selective and sensitive method for…”
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N-glycosylation of enhanced aromatic sequons to increase glycoprotein stability by Price, Joshua L., Culyba, Elizabeth K., Chen, Wentao, Murray, Amber N., Hanson, Sarah R., Wong, Chi-Huey, Powers, Evan T., Kelly, Jeffery W.

“…N‐glycosylation can increase the rate of protein folding, enhance thermodynamic stability, and slow protein unfolding; however, the molecular basis for these…”
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Enhanced Aromatic Sequons Increase Oligosaccharyltransferase Glycosylation Efficiency and Glycan Homogeneity by Murray, Amber N., Chen, Wentao, Antonopoulos, Aristotelis, Hanson, Sarah R., Wiseman, R. Luke, Dell, Anne, Haslam, Stuart M., Powers, David L., Powers, Evan T., Kelly, Jeffery W.

“…N-Glycosylation plays an important role in protein folding and function. Previous studies demonstrate that a phenylalanine residue introduced at the n-2…”
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Discovery and characterization of a mammalian amyloid disaggregation activity by Murray, Amber N., Solomon, James P., Wang, Ya‐Juan, Balch, William E., Kelly, Jeffery W.

“…The formation of amyloid, a cross‐β‐sheet fibrillar aggregate, is associated with a variety of aging‐associated degenerative diseases. Herein, we report the…”
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The 8 and 5 kDa Fragments of Plasma Gelsolin Form Amyloid Fibrils by a Nucleated Polymerization Mechanism, while the 68 kDa Fragment Is Not Amyloidogenic by Solomon, James P, Yonemoto, Isaac T, Murray, Amber N, Price, Joshua L, Powers, Evan T, Balch, William E, Kelly, Jeffery W

“…Familial amyloidosis of Finnish type (FAF), or gelsolin amyloidosis, is a systemic amyloid disease caused by a mutation (D187N/Y) in domain 2 of human plasma…”
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Abstract 3110: In depth comparison of cell free DNA blood collection tubes by Desharnais, Joel, Vasquez, Jacob M., Reshatoff, Katya J., Bui, Quyen, Chen, Han-Mei, Tsvetanova, Billyana, Lu, Jerry, Murray, Amber N., Costa, Gina L.

“…Abstract Liquid biopsy continues to gain traction as a minimally invasive method to monitor biomarkers associated with malignancy and metastasis such as…”
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Abstract 4598: A comprehensive assessment of the impact of preanalytical variables on cell free DNA and circulating tumor cells in blood by Pottekat, Anita, Allawi, Hatim T., Boragine, Genna T., Kaiser, Michael W., Sander, Tamara, Krueger, Chateen, Bruinsma, Janelle J., Murray, Amber N.

“…Abstract Liquid biopsy continues to gain traction as a minimally invasive method to monitor biomarkers associated with malignancy and metastasis. A simple…”
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A Kinetic Aggregation Assay Enabling Selective and Sensitive Aβ Amyloid Quantification in Cells and Tissues by Du, Deguo, Murray, Amber N., Cohen, Ehud, Kim, Hyun-Eui, Simkovsky, Ryan, Dillin, Andrew, Kelly, Jeffery W.

“…The process of amyloid-β (Aβ) fibril formation is genetically and pathologically linked to Alzheimer's disease (AD). Thus, a selective and sensitive method for…”
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Promoting Protein Folding with N-glycosylation and Amyloid Disaggregation by Murray, Amber N

“…Proteins must fold into complex three-dimensional structures to function. Considerable cellular resources are spent to facilitate protein folding. Enzymes…”
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Promoting Protein Folding with N-glycosylation and Amyloid Disaggregation by Murray, Amber N

“…Proteins must fold into complex three-dimensional structures to function. Considerable cellular resources are spent to facilitate protein folding. Enzymes…”
Get full text