Search Results - "Murrah, Kyle A"
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A live‐attenuated pneumococcal vaccine elicits CD4+ T‐cell dependent class switching and provides serotype independent protection against acute otitis media
Published in EMBO molecular medicine (01-01-2014)“…Acute otitis media (AOM) caused by Streptococcus pneumoniae remains one of the most common infectious diseases worldwide despite widespread vaccination. A…”
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Residence of Streptococcus pneumoniae and Moraxella catarrhalis within polymicrobial biofilm promotes antibiotic resistance and bacterial persistence in vivo
Published in Pathogens and disease (01-04-2014)“…Abstract Otitis media (OM) is an extremely common pediatric ailment caused by opportunists that reside within the nasopharynx. Inflammation within the upper…”
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Peroxiredoxin-glutaredoxin and catalase promote resistance of nontypeable Haemophilus influenzae 86-028NP to oxidants and survival within neutrophil extracellular traps
Published in Infection and immunity (01-01-2015)“…Nontypeable Haemophilus influenzae (NTHI) is a common commensal and opportunistic pathogen of the human airways. For example, NTHI is a leading cause of otitis…”
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Nonencapsulated Streptococcus pneumoniae causes otitis media during single-species infection and during polymicrobial infection with nontypeable Haemophilus influenzae
Published in Pathogens and disease (01-07-2015)“…Streptococcus pneumoniae strains lacking capsular polysaccharide have been increasingly reported in carriage and disease contexts. Since most cases of otitis…”
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Influenza A virus alters pneumococcal nasal colonization and middle ear infection independently of phase variation
Published in Infection and immunity (01-11-2014)“…Streptococcus pneumoniae (pneumococcus) is both a widespread nasal colonizer and a leading cause of otitis media, one of the most common diseases of childhood…”
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Divergent Mechanisms for Passive Pneumococcal Resistance to β-Lactam Antibiotics in the Presence of Haemophilus influenzae
Published in The Journal of infectious diseases (15-02-2011)“…Background. Otitis media, for which antibiotic treatment failure is increasingly common, is a leading pediatric public health problem. Methods. In vitro and in…”
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Replication of type 5 adenovirus promotes middle ear infection by Streptococcus pneumoniae in the chinchilla model of otitis media
Published in Pathogens and disease (01-03-2015)“…Adenoviral infection is a major risk factor for otitis media. We hypothesized that adenovirus promotes bacterial ascension into the middle ear through the…”
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A live‐attenuated pneumococcal vaccine elicits CD 4 + T ‐cell dependent class switching and provides serotype independent protection against acute otitis media
Published in EMBO molecular medicine (01-01-2014)“…Acute otitis media ( AOM ) caused by Streptococcus pneumoniae remains one of the most common infectious diseases worldwide despite widespread vaccination. A…”
Get full text
Journal Article