Search Results - "Murphy, Shawn N."

Individualized prediction of COVID-19 adverse outcomes with MLHO by Estiri, Hossein, Strasser, Zachary H., Murphy, Shawn N.

“…The COVID-19 pandemic has devastated the world with health and economic wreckage. Precise estimates of adverse outcomes from COVID-19 could have led to better…”
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Data model harmonization for the All Of Us Research Program: Transforming i2b2 data into the OMOP common data model by Klann, Jeffrey G, Joss, Matthew A H, Embree, Kevin, Murphy, Shawn N

“…The All Of Us Research Program (AOU) is building a nationwide cohort of one million patients' EHR and genomic data. Data interoperability is paramount to the…”
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Out-of-system Care and Recording of Patient Characteristics Critical for Comparative Effectiveness Research by Lin, Kueiyu Joshua, Glynn, Robert J, Singer, Daniel E, Murphy, Shawn N, Lii, Joyce, Schneeweiss, Sebastian

“…BACKGROUND:It is unclear how out-of-system care or electronic health record (EHR) discontinuity (i.e., receiving care outside of an EHR system) may affect…”
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Predicting COVID-19 mortality with electronic medical records by Estiri, Hossein, Strasser, Zachary H., Klann, Jeffy G., Naseri, Pourandokht, Wagholikar, Kavishwar B., Murphy, Shawn N.

“…This study aims to predict death after COVID-19 using only the past medical information routinely collected in electronic health records (EHRs) and to…”
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A clustering approach for detecting implausible observation values in electronic health records data by Estiri, Hossein, Klann, Jeffrey G, Murphy, Shawn N

“…Identifying implausible clinical observations (e.g., laboratory test and vital sign values) in Electronic Health Record (EHR) data using rule-based procedures…”
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Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts by Liao, Katherine P, Ananthakrishnan, Ashwin N, Kumar, Vishesh, Xia, Zongqi, Cagan, Andrew, Gainer, Vivian S, Goryachev, Sergey, Chen, Pei, Savova, Guergana K, Agniel, Denis, Churchill, Susanne, Lee, Jaeyoung, Murphy, Shawn N, Plenge, Robert M, Szolovits, Peter, Kohane, Isaac, Shaw, Stanley Y, Karlson, Elizabeth W, Cai, Tianxi

“…Typically, algorithms to classify phenotypes using electronic medical record (EMR) data were developed to perform well in a specific patient population. There…”
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Data interchange using i2b2 by Klann, Jeffrey G, Abend, Aaron, Raghavan, Vijay A, Mandl, Kenneth D, Murphy, Shawn N

“…Objective Reinventing data extraction from electronic health records (EHRs) to meet new analytical needs is slow and expensive. However, each new data research…”
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Distinguishing Admissions Specifically for COVID-19 From Incidental SARS-CoV-2 Admissions: National Retrospective Electronic Health Record Study by Klann, Jeffrey G, Strasser, Zachary H, Hutch, Meghan R, Kennedy, Chris J, Marwaha, Jayson S, Morris, Michele, Samayamuthu, Malarkodi Jebathilagam, Pfaff, Ashley C, Estiri, Hossein, South, Andrew M, Weber, Griffin M, Yuan, William, Avillach, Paul, Wagholikar, Kavishwar B, Luo, Yuan, Omenn, Gilbert S, Visweswaran, Shyam, Holmes, John H, Xia, Zongqi, Brat, Gabriel A, Murphy, Shawn N

“…Admissions are generally classified as COVID-19 hospitalizations if the patient has a positive SARS-CoV-2 polymerase chain reaction (PCR) test. However,…”
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SHRINE: enabling nationally scalable multi-site disease studies by McMurry, Andrew J, Murphy, Shawn N, MacFadden, Douglas, Weber, Griffin, Simons, William W, Orechia, John, Bickel, Jonathan, Wattanasin, Nich, Gilbert, Clint, Trevvett, Philip, Churchill, Susanne, Kohane, Isaac S

“…Results of medical research studies are often contradictory or cannot be reproduced. One reason is that there may not be enough patient subjects available for…”
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The Association Between Arthralgia and Vedolizumab Using Natural Language Processing by Cai, Tianrun, Lin, Tzu-Chieh, Bond, Allison, Huang, Jie, Kane-Wanger, Gwendolyn, Cagan, Andrew, Murphy, Shawn N, Ananthakrishnan, Ashwin N, Liao, Katherine P

“…Abstract Background The gut-selective nature of vedolizumab has raised questions regarding increased joint pain or arthralgia with its use in inflammatory…”
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Combining clinical and genomics queries using i2b2 - Three methods by Murphy, Shawn N, Avillach, Paul, Bellazzi, Riccardo, Phillips, Lori, Gabetta, Matteo, Eran, Alal, McDuffie, Michael T, Kohane, Isaac S

“…We are fortunate to be living in an era of twin biomedical data surges: a burgeoning representation of human phenotypes in the medical records of our…”
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Comparative Effectiveness of Infliximab and Adalimumab in Crohn's Disease and Ulcerative Colitis by Ananthakrishnan, Ashwin N, Cagan, Andrew, Cai, Tianxi, Gainer, Vivian S, Shaw, Stanley Y, Savova, Guergana, Churchill, Susanne, Karlson, Elizabeth W, Kohane, Isaac, Liao, Katherine P, Murphy, Shawn N

“…The availability of monoclonal antibodies to tumor necrosis factor α has revolutionized management of Crohn's disease (CD) and ulcerative colitis. However,…”
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Rare Copy Number Variation in Treatment-Resistant Major Depressive Disorder by O’Dushlaine, Colm, Ripke, Stephan, Ruderfer, Douglas M, Hamilton, Steven P, Fava, Maurizio, Iosifescu, Dan V, Kohane, Isaac S, Churchill, Susanne E, Castro, Victor M, Clements, Caitlin C, Blumenthal, Sarah R, Murphy, Shawn N, Smoller, Jordan W, Perlis, Roy H

“…Background While antidepressant treatment response appears to be partially heritable, no consistent genetic associations have been identified. Large, rare copy…”
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Claims-Based Algorithms for Identifying Patients With Pulmonary Hypertension: A Comparison of Decision Rules and Machine-Learning Approaches by Ong, Mei-Sing, Klann, Jeffrey G, Lin, Kueiyu Joshua, Maron, Bradley A, Murphy, Shawn N, Natter, Marc D, Mandl, Kenneth D

“…Background Real-world healthcare data are an important resource for epidemiologic research. However, accurate identification of patient cohorts-a crucial first…”
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Association between inflammation and systolic blood pressure in RA compared to patients without RA by Yu, Zhi, Kim, Seoyoung C, Vanni, Kathleen, Huang, Jie, Desai, Rishi, Murphy, Shawn N, Solomon, Daniel H, Liao, Katherine P

“…The relationship between inflammation and blood pressure (BP) has been studied mainly in the general population. In this study, we examined the association…”
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Extracting principal diagnosis, co-morbidity and smoking status for asthma research: evaluation of a natural language processing system by Zeng, Qing T, Goryachev, Sergey, Weiss, Scott, Sordo, Margarita, Murphy, Shawn N, Lazarus, Ross

“…The text descriptions in electronic medical records are a rich source of information. We have developed a Health Information Text Extraction (HITEx) tool and…”
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Genetic Basis of Autoantibody Positive and Negative Rheumatoid Arthritis Risk in a Multi-ethnic Cohort Derived from Electronic Health Records by Kurreeman, Fina, Liao, Katherine, Chibnik, Lori, Hickey, Brendan, Stahl, Eli, Gainer, Vivian, Li, Gang, Bry, Lynn, Mahan, Scott, Ardlie, Kristin, Thomson, Brian, Szolovits, Peter, Churchill, Susanne, Murphy, Shawn N., Cai, Tianxi, Raychaudhuri, Soumya, Kohane, Isaac, Karlson, Elizabeth, Plenge, Robert M.

“…Discovering and following up on genetic associations with complex phenotypes require large patient cohorts. This is particularly true for patient cohorts of…”
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Morphological variables associated with ruptured basilar tip aneurysms by Zhang, Jian, Can, Anil, Lai, Pui Man Rosalind, Mukundan, Srinivasan, Castro, Victor M., Dligach, Dmitriy, Finan, Sean, Gainer, Vivian S., Shadick, Nancy A., Savova, Guergana, Murphy, Shawn N., Cai, Tianxi, Weiss, Scott T., Du, Rose

“…Morphological factors of intracranial aneurysms and the surrounding vasculature could affect aneurysm rupture risk in a location specific manner. Our goal was…”
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Age and morphology of posterior communicating artery aneurysms by Zhang, Jian, Can, Anil, Lai, Pui Man Rosalind, Mukundan, Srinivasan, Castro, Victor M., Dligach, Dmitriy, Finan, Sean, Yu, Sheng, Gainer, Vivian S., Shadick, Nancy A., Savova, Guergana, Murphy, Shawn N., Cai, Tianxi, Weiss, Scott T., Du, Rose

“…Risk of intracranial aneurysm rupture could be affected by geometric features of intracranial aneurysms and the surrounding vasculature in a location specific…”
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Tobacco use and age are associated with different morphologic features of anterior communicating artery aneurysms by Zhang, Jian, Lai, Pui Man Rosalind, Can, Anil, Mukundan, Srinivasan, Castro, Victor M., Dligach, Dmitriy, Finan, Sean, Gainer, Vivian S., Shadick, Nancy A., Savova, Guergana, Murphy, Shawn N., Cai, Tianxi, Weiss, Scott T., Du, Rose

“…We present a cohort of patients with anterior communicating artery (ACoA) aneurysms to investigate morphological characteristics and clinical factors…”
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