Search Results - "Murphy, Ryan J."
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Growth and adaptation mechanisms of tumour spheroids with time-dependent oxygen availability
Published in PLoS computational biology (01-01-2023)“…Tumours are subject to external environmental variability. However, in vitro tumour spheroid experiments, used to understand cancer progression and develop…”
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Quantitative analysis of tumour spheroid structure
Published in eLife (29-11-2021)“…Tumour spheroids are common in vitro experimental models of avascular tumour growth. Compared with traditional two-dimensional culture, tumour spheroids more…”
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Suitability of the new Aryl-Ketone-Polymer indicated for removable partial dentures: Analysis of elastic properties and bond strength to denture resin
Published in Dental Materials Journal (30-07-2020)“…Elastic properties of Aryl-Ketone-Polymer (UAKP) and tensile bond strength (TBS) to denture resin (PalaXpress) were tested. Indentation modulus (EIT) and…”
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4
Deformation and retentive force following in vitro cyclic fatigue of cobalt-chrome and aryl ketone polymer (AKP) clasps
Published in Dental materials (01-06-2019)“…[Display omitted] •Novel methods have successfully measured force in situ and 3D deformation of clasps.•CoCr clasps distort more than aryl ketone polymer (AKP)…”
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Computationally efficient framework for diagnosing, understanding and predicting biphasic population growth
Published in Journal of the Royal Society interface (07-12-2022)“…Throughout the life sciences, biological populations undergo multiple phases of growth, often referred to as for the commonly encountered situation involving…”
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Automatic annotation of hip anatomy in fluoroscopy for robust and efficient 2D/3D registration
Published in International journal for computer assisted radiology and surgery (01-05-2020)“…Purpose Fluoroscopy is the standard imaging modality used to guide hip surgery and is therefore a natural sensor for computer-assisted navigation. In order to…”
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Designing and interpreting 4D tumour spheroid experiments
Published in Communications biology (24-01-2022)“…Tumour spheroid experiments are routinely used to study cancer progression and treatment. Various and inconsistent experimental designs are used, leading to…”
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Effect on Injuries of Assigning Shoes Based on Foot Shape in Air Force Basic Training
Published in American journal of preventive medicine (01-01-2010)“…Background This study examined whether assigning running shoes based on the shape of the bottom of the foot (plantar surface) influenced injury risk in Air…”
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A Particle Model for Prediction of Cement Infiltration of Cancellous Bone in Osteoporotic Bone Augmentation
Published in PloS one (26-06-2013)“…Femoroplasty is a potential preventive treatment for osteoporotic hip fractures. It involves augmenting mechanical properties of the femur by injecting…”
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In Vitro Biofilm Formation on Aryl Ketone Polymer (AKP), A New Denture Material, Compared with That on Three Traditional Dental Denture Materials
Published in International journal of dentistry (2021)“…Control of denture plaque biofilms is a practical approach to preventing persistent oral infections such as denture stomatitis. Objectives. This study compared…”
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Dynamic light scattering investigations of nanoparticle aggregation following a light-induced pH jump
Published in The Journal of chemical physics (21-05-2010)“…There are many important processes where the stability of nanoparticles can change due to changes in solution environment. These processes are often difficult…”
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Mechanical Model of Dexterous Continuum Manipulators With Compliant Joints and Tendon/External Force Interactions
Published in IEEE/ASME transactions on mechatronics (01-02-2017)“…Dexterous continuum manipulators (DCMs) have been widely adopted for minimally- and less-invasive surgery. During the operation, these DCMs interact with…”
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13
Modelling count data with partial differential equation models in biology
Published in Journal of theoretical biology (07-03-2024)“…Partial differential equation (PDE) models are often used to study biological phenomena involving movement-birth-death processes, including ecological…”
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Implementing measurement error models with mechanistic mathematical models in a likelihood-based framework for estimation, identifiability analysis and prediction in the life sciences
Published in Journal of the Royal Society interface (31-01-2024)“…Throughout the life sciences, we routinely seek to interpret measurements and observations using parametrized mechanistic mathematical models. A fundamental…”
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Measuring and Modelling the Epithelial- Mesenchymal Hybrid State in Cancer: Clinical Implications
Published in Cells, tissues, organs (2022)“…The epithelial-mesenchymal (E/M) hybrid state has emerged as an important mediator of elements of cancer progression, facilitated by epithelial mesenchymal…”
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Shape Tracking of a Dexterous Continuum Manipulator Utilizing Two Large Deflection Shape Sensors
Published in IEEE sensors journal (01-10-2015)“…Dexterous continuum manipulators (DCMs) can largely increase the reachable region and steerability for minimally and less invasive surgery. Many such…”
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Formation and Growth of Co-Culture Tumour Spheroids: New Compartment-Based Mathematical Models and Experiments
Published in Bulletin of mathematical biology (01-01-2024)“…Co-culture tumour spheroid experiments are routinely performed to investigate cancer progression and test anti-cancer therapies. Therefore, methods to…”
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Mechanical Cell Competition in Heterogeneous Epithelial Tissues
Published in Bulletin of mathematical biology (26-09-2020)“…Mechanical cell competition is important during tissue development, cancer invasion, and tissue ageing. Heterogeneity plays a key role in practical…”
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A biomechanically-guided planning and execution paradigm for osteoporotic hip augmentation: Experimental evaluation of the biomechanics and temperature-rise
Published in Clinical biomechanics (Bristol) (01-07-2021)“…Augmentation of the proximal femur with bone cement (femoroplasty) has been identified as a potential preventive approach to reduce the risk of fracture…”
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Prospects for quantitative computed tomography imaging in the presence of foreign metal bodies using statistical image reconstruction
Published in Medical physics (Lancaster) (01-10-2002)“…X-ray computed tomography (CT) images of patients bearing metal intracavitary applicators or other metal foreign objects exhibit severe artifacts including…”
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