Search Results - "Murphy, R.M."

Beta-amyloid peptide blocks the fast-inactivating K+ current in rat hippocampal neurons by Good, T.A., Smith, D.O., Murphy, R.M.

“…Deposition of beta-amyloid peptide (A beta) in senile plaques is a hallmark of Alzheimer disease neuropathology. Chronic exposure of neuronal cultures to…”
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Light scattering analysis of fibril growth from the amino-terminal fragment beta(1–28) of beta-amyloid peptide by Shen, C.L., Scott, G.L., Merchant, F., Murphy, R.M.

“…beta-Amyloid protein (beta-A/4) is the major protein component of Alzheimer disease-related senile plaques and has been postulated to be a significant…”
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Effect of acid predissolution on fibril size and fibril flexibility of synthetic beta-amyloid peptide by Shen, C.L., Fitzgerald, M.C., Murphy, R.M.

“…beta-amyloid peptide (A beta) is the major protein component of senile plaques and cerebrovascular amyloid deposits in Alzheimer's patients. Several…”
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Assessing nitrous oxide emissions in time and space with minimal uncertainty using static chambers and eddy covariance from a temperate grassland by Murphy, R.M., Richards, K.G., Krol, D.J., Gebremichael, A.W., Lopez-Sangil, L., Rambaud, J., Cowan, N., Lanigan, G.J., Saunders, M.

“…•N2O emissions were measured by eddy covariance (EC) and static chambers (CH).•Mean daily CH fluxes were calculated by arithmetic and Bayesian statistics.•CH…”
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Solvent effects on self-assembly of beta-amyloid peptide by Shen, C.L., Murphy, R.M.

“…beta-amyloid peptide (A beta) is the primary protein component of senile plaques in Alzheimer's disease patients. Synthetic A beta spontaneously assembles into…”
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Molecular and morphological phylogenetics of the digitate-tubered clade within subtribe Orchidinae s.s. (Orchidaceae: Orchideae) by Bateman, Richard M., Murphy, Alexander R. M., Hollingsworth, Peter M., Hart, Michelle L., Denholm, Ian, Rudall, Paula J.

“…The digitate-tubered clade (Dactylorhiza s.l. plus Gymnadenia s.l.) within subtribe Orchidinae is an important element of the North-temperate orchid flora and…”
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Predicting Solvent and Aggregation Effects of Peptides Using Group Contribution Calculations by Kim, Jin Ryoun, Gibson, Todd J., Murphy, Regina M.

“…Assembly of proteins and peptides into amyloid fibrils is characteristic of the pathology of a number of degenerative diseases, of which perhaps the best known…”
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Coupled cellular trafficking and diffusional limitations in delivery of immunotoxins to multicell tumor spheroids by Wenning, Larissa A., Murphy, Regina M.

“…Immunotoxins have the potential to be powerful tools for selective cell killing, but their lack of clinical success against solid tumors indicates a need to…”
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Establishment of a functional genomics platform for Leifsonia xyli subsp. xyli by Brumbley, S.M, Petrasovits, L.A, Murphy, R.M, Nagel, R.J, Candy, J.M, Hermann, S.R

“…Leifsonia xyli subsp. xyli, the causal agent of ratoon stunting disease in sugarcane, is a xylem-limited, nutritionally fastidious, slow growing, gram-positive…”
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Design of a pH-sensitive pore-forming peptide with improved performance by Haas, D.H., Murphy, R.M.

“…:  GALA is a 30 residue synthetic peptide designed to interact with membranes in a pH‐sensitive manner, with potential applications for intracellular drug and…”
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Aggregation State-Dependent Binding of β-Amyloid Peptide to Protein and Lipid Components of Rat Cortical Homogenates by Good, T.A., Murphy, R.M.

“…β-amyloid peptide (Aβ) is the primary protein component of senile plaques in Alzheimer′s disease. Aβ is toxic to neuronal cell cultures, although the mechanism…”
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Templated assembly of the pH-sensitive membrane-lytic peptide GALA by Haas, D.H., Murphy, R.M.

“…:  Delivery of protein or nucleic acid therapeutics into intracellular compartments may require facilitation to allow these macromolecules to cross otherwise…”
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Quantitative analysis of protein synthesis inhibition and recovery in CRM107 immunotoxin-treated HeLa cells by Wenning, Larissa A., Yazdi, Parvin T., Murphy, Regina M.

“…Previously a mathematical model was proposed that quantitatively related protein synthesis inhibition kinetics of antitransferrin receptor–gelonin immunotoxins…”
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AM fiber-optic local loop distribution in Cologne, West Germany by Murphy, R.M.

“…An AM fiber-optic distribution system developed for the Deutsche Bundespost of the Federal Republic of Germany is described. This is the first deployed video…”
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Size and structure of antigen-antibody complexes. Electron microscopy and light scattering studies by Murphy, R.M., Slayter, H., Schurtenberger, P., Chamberlin, R.A., Colton, C.K., Yarmush, M.L.

“…Size parameters of model antigen-antibody (Ag-Ab) complexes formed by the interaction of bovine serum albumin (BSA) and pairs of monoclonal anti-BSA antibodies…”
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Wetting properties of the sulphur electrolyte in sodium ? sulphur batteries by Janz, G. J., Murphy, R. M., Spiak, W. A.

“…In the sulphur electrode of sodium--sulphur cells, carbon surfaces (generally as yarns or felts) are used as current collectors. During the charging cycle,…”
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The Human Early Pregnancy Factor/Chaperonin 10 Gene Family by Summers, K.M., Murphy, R.M., Webb, G.C., Peters, G.B., Morton, H., Cassady, A.I., Cavanagh, A.C.

“…cDNA clones corresponding to the sequence for human early pregnancy factor were isolated from a human melanoma library and hybridized to DNA digested with four…”
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