Search Results - "Murphy, Niall"

Microglia disrupt mesolimbic reward circuitry in chronic pain by Taylor, Anna M W, Castonguay, Annie, Taylor, Alison J, Murphy, Niall P, Ghogha, Atefeh, Cook, Christopher, Xue, Lihua, Olmstead, Mary C, De Koninck, Yves, Evans, Christopher J, Cahill, Catherine M

“…Chronic pain attenuates midbrain dopamine (DA) transmission, as evidenced by a decrease in opioid-evoked DA release in the ventral striatum, suggesting that…”
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Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism by Peñagarikano, Olga, Lázaro, María T, Lu, Xiao-Hong, Gordon, Aaron, Dong, Hongmei, Lam, Hoa A, Peles, Elior, Maidment, Nigel T, Murphy, Niall P, Yang, X William, Golshani, Peyman, Geschwind, Daniel H

“…Mouse models of neuropsychiatric diseases provide a platform for mechanistic understanding and development of new therapies. We previously demonstrated that…”
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Sex-specific enhancement of palatability-driven feeding in adolescent rats by Marshall, Andrew T, Liu, Angela T, Murphy, Niall P, Maidment, Nigel T, Ostlund, Sean B

“…It has been hypothesized that brain development during adolescence perturbs reward processing in a way that may ultimately contribute to the risky decision…”
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Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward by Cui, Yijun, Ostlund, Sean B, James, Alex S, Park, Chang Sin, Ge, Weihong, Roberts, Kristofer W, Mittal, Nitish, Murphy, Niall P, Cepeda, Carlos, Kieffer, Brigitte L, Levine, Michael S, Jentsch, James David, Walwyn, Wendy M, Sun, Yi E, Evans, Christopher J, Maidment, Nigel T, Yang, X William

“…μ-opioid receptor (MOR) was previously shown to be necessary for opiate reward, analgesia and dependence. To better understand the specific anatomical and cell…”
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Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease by Fitzmaurice, Arthur G., Rhodes, Shannon L., Lulla, Aaron, Murphy, Niall P., Lam, Hoa A., O'Donnell, Kelley C., Barnhill, Lisa, Casida, John E., Cockburn, Myles, Sagasti, Alvaro, Stahl, Mark C., Maidment, Nigel T., Ritz, Beate, Bronstein, Jeff M.

“…Parkinson disease (PD) is a neurodegenerative disorder particularly characterized by the loss of dopaminergic neurons in the substantia nigra . Pesticide…”
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Voluntary alcohol intake alters the motivation to seek intravenous oxycodone and neuronal activation during the reinstatement of oxycodone and sucrose seeking by Wilkinson, Courtney S., Blount, Harrison L., Davis, Shane, Rojas, Giselle, Wu, Lizhen, Murphy, Niall P., Schwendt, Marek, Knackstedt, Lori A.

“…Opioid-alcohol polysubstance use is prevalent and worsens treatment outcomes. Here we assessed whether co-consumption of oxycodone and alcohol influence the…”
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Stochastic pulsing of gene expression enables the generation of spatial patterns in Bacillus subtilis biofilms by Nadezhdin, Eugene, Murphy, Niall, Dalchau, Neil, Phillips, Andrew, Locke, James C. W.

“…Stochastic pulsing of gene expression can generate phenotypic diversity in a genetically identical population of cells, but it is unclear whether it has a role…”
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Genetic dissection of medial habenula-interpeduncular nucleus pathway function in mice by Kobayashi, Yuki, Sano, Yoshitake, Vannoni, Elisabetta, Goto, Hiromichi, Suzuki, Hitomi, Oba, Atsuko, Kawasaki, Hiroaki, Kanba, Shigenobu, Lipp, Hans-Peter, Murphy, Niall P, Wolfer, David P, Itohara, Shigeyoshi

“…The habenular complex linking forebrain and midbrain structures is subdivided into the medial (mHb) and the lateral nuclei (lHb). The mHb is characterized by…”
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DeepQPrep: Neural Network Augmented Search for Quantum State Preparation by Selig, Patrick, Murphy, Niall, Redmond, David, Caton, Simon

“…There is an increasing interest in the area of quantum computing but developing quantum algorithms is difficult. Neural Network augmented search algorithms…”
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Involvement of Endogenous Enkephalins and β-Endorphin in Feeding and Diet-Induced Obesity by Mendez, Ian A, Ostlund, Sean B, Maidment, Nigel T, Murphy, Niall P

“…Studies implicate opioid transmission in hedonic and metabolic control of feeding, although roles for specific endogenous opioid peptides have barely been…”
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Dynamic Measurement of Extracellular Opioid Activity: Status Quo, Challenges, and Significance in Rewarded Behaviors by Murphy, Niall P

“…Opioid peptides are the endogenous ligands of opioid receptors, which are also the molecular target of naturally occurring and synthetic opiates, such as…”
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An ethogram analysis of cutaneous thermal pain sensitivity and oxycodone reward-related behaviors in rats by Brice-Tutt, Ariana C., Montgomery, Darrice S., Kramer, Cassidy M., Novotny, Peter M., Malphurs, Wendi L., Sharma, Abhisheak, Caudle, Robert. M., Bruijnzeel, Adriaan W., Setlow, Barry, Neubert, John K., Murphy, Niall P.

“…Inter-relationships between pain sensitivity, drug reward, and drug misuse are of considerable interest given that many analgesics exhibit misuse potential…”
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A Rasch Analysis of the Charcot-Marie-Tooth Neuropathy Score (CMTNS) in a Cohort of Charcot-Marie-Tooth Type 1A Patients by Wang, Wenjia, Guedj, Mickaël, Bertrand, Viviane, Foucquier, Julie, Jouve, Elisabeth, Commenges, Daniel, Proust-Lima, Cécile, Murphy, Niall P, Blin, Olivier, Magy, Laurent, Cohen, Daniel, Attarian, Shahram

“…The Charcot-Marie-Tooth Neuropathy Score (CMTNS) was developed as a main efficacy endpoint for application in clinical trials of Charcot-Marie-Tooth disease…”
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Monomethylation of Histone H4-Lysine 20 Is Involved in Chromosome Structure and Stability and Is Essential for Mouse Development by Oda, Hisanobu, Okamoto, Ikuhiro, Murphy, Niall, Chu, Jianhua, Price, Sandy M., Shen, Michael M., Torres-Padilla, Maria Elena, Heard, Edith, Reinberg, Danny

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Targeted deletion of the mouse α2 nicotinic acetylcholine receptor subunit gene (Chrna2) potentiates nicotine-modulated behaviors by Lotfipour, Shahrdad, Byun, Janet S, Leach, Prescott, Fowler, Christie D, Murphy, Niall P, Kenny, Paul J, Gould, Thomas J, Boulter, Jim

“…Baseline and nicotine-modulated behaviors were assessed in mice harboring a null mutant allele of the nicotinic acetylcholine receptor (nAChR) subunit gene α2…”
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Decreased consumption of sweet fluids in mu opioid receptor knockout mice: a microstructural analysis of licking behavior by Ostlund, Sean B., Kosheleff, Alisa, Maidment, Nigel T., Murphy, Niall P.

“…Rationale Evidence suggests that the palatability of food (i.e., the hedonic impact produced by its sensory features) can promote feeding and may underlie…”
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Affective taste responses in the presence of reward- and aversion-conditioned stimuli and their relationship to psychomotor sensitization and place conditioning by Cagniard, Barbara, Murphy, Niall P.

“…▸ Rewarding and aversive stimuli produce conditioned place preferences and aversions. ▸ Affective experience of tastants can be assessed by studying orofacial…”
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Live-Cell Chromosome Dynamics and Outcome of X Chromosome Pairing Events during ES Cell Differentiation by Masui, Osamu, Bonnet, Isabelle, Le Baccon, Patricia, Brito, Isabel, Pollex, Tim, Murphy, Niall, Hupé, Philippe, Barillot, Emmanuel, Belmont, Andrew S., Heard, Edith

“…Random X inactivation represents a paradigm for monoallelic gene regulation during early ES cell differentiation. In mice, the choice of X chromosome to…”
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Endogenous Nociceptin (Orphanin FQ) Suppresses Basal Hedonic State and Acute Reward Responses to Methamphetamine and Ethanol, but Facilitates Chronic Responses by SAKOORI, Kazuto, MURPHY, Niall P

“…The opioid peptide nociceptin (orphanin FQ) suppresses drug reward, drug self-administration, and impedes some of the processes believed to underlie the…”
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Targeted Deletion of the Mouse alpha 2 Nicotinic Acetylcholine Receptor Subunit Gene (Chrna2) Potentiates Nicotine-Modulated Behaviors by Lotfipour, Shahrdad, Byun, Janet S, Leach, Prescott, Fowler, Christie D, Murphy, Niall P, Kenny, Paul J, Gould, Thomas J, Boulter, Jim

“…Baseline and nicotine-modulated behaviors were assessed in mice harboring a null mutant allele of the nicotinic acetylcholine receptor (nAChR) subunit gene…”
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