Search Results - "Murphy, M. M."
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Making the Right Tools for the Job With Adele Clarke
Published in Science, technology, & human values (01-11-2024)“…This essay is part of a Thematic Collection of Science, Technology & Human Values on the work of Adele E. Clarke (1945–2024)…”
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HPA axis in major depression: cortisol, clinical symptomatology and genetic variation predict cognition
Published in Molecular psychiatry (01-04-2017)“…The hypothalamic–pituitary–adrenal (HPA) axis has been implicated in the pathophysiology of a variety of mood and cognitive disorders. Neuroendocrine studies…”
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Functions of Murine Dendritic Cells
Published in Immunity (Cambridge, Mass.) (18-10-2016)“…Dendritic cells (DCs) play critical roles in activating innate immune cells and initiating adaptive immune responses. The functions of DCs were originally…”
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4
Amyloid-Beta Solubility in the Treatment of Alzheimer’s Disease
Published in The New England journal of medicine (25-01-2018)“…There is general agreement that Alzheimer’s disease will become a crisis by the middle of the century. The Alzheimer’s Association estimates that 5 million…”
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The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering
Published in Biomaterials (01-01-2010)“…Abstract In the literature there are conflicting reports on the optimal scaffold mean pore size required for successful bone tissue engineering. This study set…”
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Dendritic cells in cancer immunology
Published in Cellular & molecular immunology (01-01-2022)“…The clinical success of immune checkpoint therapy (ICT) has produced explosive growth in tumor immunology research because ICT was discovered through basic…”
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Mitochondrial dynamics, a new therapeutic target for Triple Negative Breast Cancer
Published in Biochimica et biophysica acta. Reviews on cancer (01-04-2021)“…Triple Negative Breast Cancer (TNBC) is an aggressive tumour with patients survival rarely exceeding five years. TNBC tumours are larger in size, more…”
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Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow
Published in Cell stem cell (07-08-2014)“…Studies of the identity and physiological function of mesenchymal stromal cells (MSCs) have been hampered by a lack of markers that permit both prospective…”
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CURRENT STATE OF THE ART HISTORIC BUILDING INFORMATION MODELLING
Published in International archives of the photogrammetry, remote sensing and spatial information sciences. (18-08-2017)“…In an extensive review of existing literature a number of observations were made in relation to the current approaches for recording and modelling existing…”
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Specialized diterpenoid metabolism in monocot crops: Biosynthesis and chemical diversity
Published in Phytochemistry (Oxford) (01-04-2020)“…Among the myriad specialized metabolites that plants employ to mediate interactions with their environment, diterpenoids form a chemically diverse group with…”
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Alzheimer's disease and the amyloid-beta peptide
Published in Journal of Alzheimer's disease (2010)“…Alzheimer's disease (AD) pathogenesis is widely believed to be driven by the production and deposition of the amyloid-beta peptide (Abeta). For many years,…”
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Describing the brain in autism in five dimensions--magnetic resonance imaging-assisted diagnosis of autism spectrum disorder using a multiparameter classification approach
Published in The Journal of neuroscience (11-08-2010)“…Autism spectrum disorder (ASD) is a neurodevelopmental condition with multiple causes, comorbid conditions, and a wide range in the type and severity of…”
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The Structural Basis of Necroptotic Cell Death Signaling
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01-01-2019)“…The recent implication of the cell death pathway, necroptosis, in innate immunity and a range of human pathologies has led to intense interest in the…”
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Neuroimaging in autism spectrum disorder: brain structure and function across the lifespan
Published in Lancet neurology (01-11-2015)“…Summary Over the past decade, in-vivo MRI studies have provided many invaluable insights into the neural substrates underlying autism spectrum disorder (ASD),…”
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A Validated Regulatory Network for Th17 Cell Specification
Published in Cell (12-10-2012)“…Th17 cells have critical roles in mucosal defense and are major contributors to inflammatory disease. Their differentiation requires the nuclear hormone…”
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Chemokines act as phosphatidylserine-bound "find-me" signals in apoptotic cell clearance
Published in PLoS biology (26-05-2021)“…Removal of apoptotic cells is essential for maintenance of tissue homeostasis. Chemotactic cues termed "find-me" signals attract phagocytes toward apoptotic…”
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Genetic models of human and mouse dendritic cell development and function
Published in Nature reviews. Immunology (01-02-2021)“…Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenitors that have numerous shared characteristics between mice and humans. Human…”
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Contribution of isoprene-derived organosulfates to free tropospheric aerosol mass
Published in Proceedings of the National Academy of Sciences - PNAS (14-12-2010)“…Recent laboratory studies have demonstrated that isoprene oxidation products can partition to atmospheric aerosols by reacting with condensed phase sulfuric…”
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Transcriptional control of dendritic cell development
Published in Advances in immunology (2013)“…Dendritic cells (DCs) drive both adaptive and innate immunity. Recent findings support the notion that distinct subsets of classical DCs favor alternative…”
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Specificity through cooperation: BATF–IRF interactions control immune-regulatory networks
Published in Nature reviews. Immunology (01-07-2013)“…Key Points Basic leucine zipper transcription factor ATF-like (BATF), BATF2 and BATF3 are basic leucine zipper (bZIP) proteins that form heterodimers with JUN…”
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