Search Results - "Murphy, M. E."

Type-2 copper-containing enzymes by MacPherson, I. S, Murphy, M. E. P

“…Type-2 Cu sites are found in all the major branches of life and are often involved in the catalysis of oxygen species. Four type-2 Cu protein families are…”
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Outpatient visits before and after Lyme disease diagnosis in a Maryland employer-based health plan by Rebman, Alison W, Yang, Ting, Wang, Lin, Marsteller, Jill A, Murphy, Shannon M. E, Uriyo, Maria, Aucott, John N

“…Abstract Background Insurance claims data have been used to inform an understanding of Lyme disease epidemiology and cost of care, however few such studies…”
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Polymorphisms in the p53 pathway by Pietsch, E C, Humbey, O, Murphy, M E

“…The p53 tumor suppressor gene continues to be distinguished as the most frequently mutated gene in human cancer; this gene can be found mutated in up to 50% of…”
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Management of an unexpected appendiceal neoplasm by Murphy, E. M. A., Farquharson, S. M., Moran, B. J.

“…Background: Appendiceal neoplasms are rare and most present unexpectedly as acute appendicitis. The classification and management are confusing, and there are…”
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Polymorphic variants in the p53 pathway by Murphy, M E

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Endocinch therapy for gastro-oesophageal reflux disease: a one year prospective follow up by Mahmood, Z, McMahon, B P, Arfin, Q, Byrne, P J, Reynolds, J V, Murphy, E M, Weir, D G

“…Background: Gastro-oesophageal reflux disease (GORD) is, in the main, treated with either proton pump inhibitor (PPI) drugs or a Nissen fundoplication…”
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Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72 by Reinbold, M, Luo, J-L, Nedelko, T, Jerchow, B, Murphy, M E, Whibley, C, Wei, Q, Hollstein, M

“…Codon 72 of human p53 gene is polymorphic, encoding arginine or proline. Here we report construction of a human p53 knock-in (Hupki) mouse encoding the codon…”
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Nitric oxide hyperpolarizes rabbit mesenteric arteries via ATP-sensitive potassium channels by Murphy, M E, Brayden, J E

“…1. Nitric oxide (NO) relaxes vascular smooth muscle (VSM) by mechanisms which are not fully understood. One possibility is that NO hyperpolarizes membranes,…”
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Impact of Managing Provider Type on Severe Aortic Stenosis Management and Mortality by Pellikka, Patricia A., Padang, Ratnasari, Scott, Christopher G., Murphy, Shannon M. E., Fabunmi, Rosalind, Thaden, Jeremy J.

“…Background Many patients with symptomatic severe aortic stenosis do not undergo aortic valve replacement (AVR) despite clinical guidelines. This study analyzed…”
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Managing malaria in tuberculosis patients on fluoroquinolone-containing regimens: assessing the risk of QT prolongation [Review article] by Murphy, M. E., Singh, K. P., Laurenzi, M., Brown, M., Gillespie, S. H.

“…The role of fluoroquinolones (FQs) in the management of drug-susceptible and drug-resistant tuberculosis (TB) is under investigation. They are currently being…”
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Exporting obesity: US farm and trade policy and the transformation of the Mexican consumer food environment by Clark, Sarah E, Hawkes, Corinna, Murphy, Sophia M E, Hansen-Kuhn, Karen A, Wallinga, David

“…Obesity has reached epidemic proportions, in the United States as well as among its trade partners such as Mexico. It has been established that an "obesogenic"…”
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Key Design Considerations When Calculating Cost Savings for Population Health Management Programs in an Observational Setting by Murphy, Shannon M. E., Hough, Douglas E., Sylvia, Martha L., Dunbar, Linda J., Frick, Kevin D.

“…Objective To illustrate the impact of key quasi‐experimental design elements on cost savings measurement for population health management (PHM) programs. Data…”
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Apamin-sensitive K+ channels mediate an endothelium-dependent hyperpolarization in rabbit mesenteric arteries by Murphy, M E, Brayden, J E

“…1. Vascular endothelial cells release a variety of substances which affect the membrane potential and tone of underlying vascular smooth muscle. In the…”
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Comparison of plant- and egg yolk-based semen diluents on in vitro sperm kinematics and in vivo fertility of frozen-thawed bull semen by Murphy, E.M., O’Meara, C., Eivers, B., Lonergan, P., Fair, S.

“…Diluents using components of plant origin have been developed as an alternative to animal based extenders for the dilution of bull semen, however, it is…”
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Association of ACEI/ARB and statin prescribing patterns with mortality after Transcatheter Aortic Valve Replacement (TAVR): Findings from real-world claims data by Cubeddu, Robert J., Murphy, Shannon M.E., Asher, Craig R., Garcia, Santiago A., Granada, Juan F., Don, Creighton W., Patel, Sankalp, Albaghdadi, Mazen S., Cavalcante, João L., Coylewright, Megan, Hahn, Rebecca T., Genereux, Philippe, Yadav, Pradeep K., Thourani, Vinod H., Leon, Martin B.

“…Transcatheter aortic valve replacement (TAVR) has become the standard of care for most patients with severe aortic stenosis (AS), but the impact of medical…”
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Effect of increasing equilibration time of diluted bull semen up to 72 h prior to freezing on sperm quality parameters and calving rate following artificial insemination by Murphy, E.M., Eivers, B., O'Meara, C.M., Lonergan, P., Fair, S.

“…An equilibration period of approximately 3–4 h prior to semen cryopreservation is standard practice for maintaining membrane integrity and motility of bull…”
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Reversible Conversion of Nitroxyl Anion to Nitric Oxide by Superoxide Dismutase by Murphy, Michael E., Sies, Helmut

“…Superoxide dismutase (SOD) rapidly scavenges superoxide (O- 2) and also prolongs the vasorelaxant effects of nitric oxide (NO), thought to be the…”
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Relation of Institutional Mitral Valve Surgical Volume to Surgical and Transcatheter Outcomes in Medicare Patients by Barker, Colin M., Reynolds, Matthew R., Reardon, Michael J., Van Houten, Joanna L., Murphy, Shannon M.E., Mollenkopf, Sarah A., Feldman, Ted E.

“…There are limited data to support proposed increases to the minimum institutional mitral valve (MV) surgery volume required to begin a transcatheter mitral…”
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Quantification of subclasses of human colonic myenteric neurons by immunoreactivity to Hu, choline acetyltransferase and nitric oxide synthase by Murphy, E. M. A., Defontgalland, D., Costa, M., Brookes, S. J. H., Wattchow, D. A.

“…An accurate method to count human enteric neurons is essential to develop a comprehensive account of the classes of nerve cells responsible for gut function…”
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The p53 family and programmed cell death by Pietsch, E C, Sykes, S M, McMahon, S B, Murphy, M E

“…The p53 tumor suppressor continues to hold distinction as the most frequently mutated gene in human cancer. The ability of p53 to induce programmed cell death,…”
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