Search Results - "Murphy, Kiera"
-
1
Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice
Published in Biological psychiatry (1969) (01-10-2017)“…Abstract Background The realization that the microbiota-gut-brain axis plays a critical role in health and disease, including neuropsychiatric disorders, is…”
Get full text
Journal Article -
2
Revisiting Metchnikoff: Age-related Alterations in Microbiota-Gut-Brain Axis in the Mouse
Published in Brain, behavior, and immunity (01-10-2017)“…Highlights • The behaviour and physiology of young and aged mice were compared, with an emphasis on gut microbiota, gut permeability and markers of peripheral…”
Get full text
Journal Article -
3
Evolution of gut microbiota composition from birth to 24 weeks in the INFANTMET Cohort
Published in Microbiome (17-01-2017)“…The gut is the most extensively studied niche of the human microbiome. The aim of this study was to characterise the initial gut microbiota development of a…”
Get full text
Journal Article -
4
Estrogen-mediated gut microbiome alterations influence sexual dimorphism in metabolic syndrome in mice
Published in Microbiome (13-11-2018)“…Understanding the mechanism of the sexual dimorphism in susceptibility to obesity and metabolic syndrome (MS) is important for the development of effective…”
Get full text
Journal Article -
5
Early Gut Microbiota Perturbations Following Intrapartum Antibiotic Prophylaxis to Prevent Group B Streptococcal Disease
Published in PloS one (22-06-2016)“…The faecal microbiota composition of infants born to mothers receiving intrapartum antibiotic prophylaxis with ampicillin against group B Streptococcus was…”
Get full text
Journal Article -
6
Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism
Published in EBioMedicine (01-10-2017)“…Autism spectrum disorder (ASD) is one of the most prevalent neurodevelopmental conditions worldwide. There is growing awareness that ASD is highly comorbid…”
Get full text
Journal Article -
7
Decreased Tissue Omega-6/Omega-3 Fatty Acid Ratio Prevents Chemotherapy-Induced Gastrointestinal Toxicity Associated with Alterations of Gut Microbiome
Published in International journal of molecular sciences (10-05-2022)“…Gastrointestinal toxicity (GIT) is a debilitating side effect of Irinotecan (CPT-11) and limits its clinical utility. Gut dysbiosis has been shown to mediate…”
Get full text
Journal Article -
8
Exploring the Gut Microbiota and Cardiovascular Disease
Published in Metabolites (29-07-2021)“…Cardiovascular disease (CVD) has been classified as one of the leading causes of morbidity and mortality worldwide. CVD risk factors include smoking,…”
Get full text
Journal Article -
9
Probiotics, Prebiotics, and Synbiotics for the Prevention of Necrotizing Enterocolitis
Published in Frontiers in nutrition (Lausanne) (07-09-2021)“…Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality in preterm infants. The exact mechanism by which NEC develops is poorly understood…”
Get full text
Journal Article -
10
Bifidobacterium longum counters the effects of obesity: Partial successful translation from rodent to human
Published in EBioMedicine (01-01-2021)“…The human gut microbiota has emerged as a key factor in the development of obesity. Certain probiotic strains have shown anti-obesity effects. The objective of…”
Get full text
Journal Article -
11
Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota
Published in Marine drugs (20-06-2018)“…Accumulating evidence demonstrates that dietary supplementation with functional food ingredients play a role in systemic and brain health as well as in healthy…”
Get full text
Journal Article -
12
Microbiome and metabolome modifying effects of several cardiovascular disease interventions in apo-E -/- mice
Published in Microbiome (13-03-2017)“…There is strong evidence indicating that gut microbiota have the potential to modify, or be modified by the drugs and nutritional interventions that we rely…”
Get full text
Journal Article -
13
The individual-specific and diverse nature of the preterm infant microbiota
Published in Archives of disease in childhood. Fetal and neonatal edition (01-07-2013)“…To examine the composition of the evolving microbiota of preterm infants at weeks 2 and 4 of life. The paediatric intensive care unit of the Cork University…”
Get more information
Journal Article -
14
Protocol for a prospective cohort study exploring the gut microbiota of infants with congenital heart disease undergoing cardiopulmonary bypass (the GuMiBear study)
Published in BMJ open (31-03-2023)“…IntroductionThe gut microbiota develops from birth and matures significantly during the first 24 months of life, playing a major role in infant health and…”
Get full text
Journal Article -
15
Genome mining for radical SAM protein determinants reveals multiple sactibiotic-like gene clusters
Published in PloS one (08-07-2011)“…Thuricin CD is a two-component bacteriocin produced by Bacillus thuringiensis that kills a wide range of clinically significant Clostridium difficile. This…”
Get full text
Journal Article -
16
The gut microbiota composition in dichorionic triplet sets suggests a role for host genetic factors
Published in PloS one (14-04-2015)“…Monozygotic and dizygotic twin studies investigating the relative roles of host genetics and environmental factors in shaping gut microbiota composition have…”
Get full text
Journal Article -
17
Pain after upper limb surgery under peripheral nerve block is associated with gut microbiome composition and diversity
Published in Neurobiology of pain (01-08-2021)“…•Postoperative pain is associated with gut microbiota composition and diversity.•Analgesic consumption is inversely correlated with alpha diversity.•Further…”
Get full text
Journal Article -
18
The Composition of Human Milk and Infant Faecal Microbiota Over the First Three Months of Life: A Pilot Study
Published in Scientific reports (17-01-2017)“…Human milk contains a diverse array of bioactives and is also a source of bacteria for the developing infant gut. The aim of this study was to characterize the…”
Get full text
Journal Article -
19
The microbiome modulating potential of superheated steam (SHS) treatment of dietary fibres
Published in Innovative food science & emerging technologies (01-08-2022)“…In this study, wheat and oat bran fibres were used to investigate the potential beneficial prebiotic-enhancing effects of superheated steam (SHS) treatment…”
Get full text
Journal Article -
20
Omega-3 polyunsaturated fatty acids critically regulate behaviour and gut microbiota development in adolescence and adulthood
Published in Brain, behavior, and immunity (01-01-2017)“…Highlights • Maternal and lifelong omega-3 deficiency impairs early-life communicative behaviour, adult social behaviour and augments adult depression-like…”
Get full text
Journal Article