Search Results - "Murphy, Jiayuan"

The Cardiac Dysfunction Caused by Metabolic Alterations in Alzheimer's Disease by Murphy, Jiayuan, Le, Tran Ngoc Van, Fedorova, Julia, Yang, Yi, Krause-Hauch, Meredith, Davitt, Kayla, Zoungrana, Linda Ines, Fatmi, Mohammad Kasim, Lesnefsky, Edward J, Li, Ji, Ren, Di

“…A progressive defect in the energy generation pathway is implicated in multiple aging-related diseases, including cardiovascular conditions and Alzheimer's…”
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Abstract 10237: Activated Protein C Protects Neurons from Alzheimer’s Disease-Related Changes Through Reduction of Tau Hyperphosphorylation by Murphy, Jiayuan, Le, Van, Davitt, Kayla, Logan, Cole, Ren, Di, Li, Ji

“…IntroductionActivated protein C (APC) is a blood serine protease that has been shown to have neuroprotective function via its downstream signaling cascade…”
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Alterations in mitochondrial dynamics with age‐related Sirtuin1/Sirtuin3 deficiency impair cardiomyocyte contractility by Zhang, Jingwen, He, Zhibin, Fedorova, Julia, Logan, Cole, Bates, Lauryn, Davitt, Kayla, Le, Van, Murphy, Jiayuan, Li, Melissa, Wang, Mingyi, Lakatta, Edward G., Ren, Di, Li, Ji

“…Sirtuin1 (SIRT1) and Sirtuin3 (SIRT3) protects cardiac function against ischemia/reperfusion (I/R) injury. Mitochondria are critical in response to myocardial…”
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Abstract 12199: Sirtuin1 Mediates Pressure Overload-Induced Cardiac Pathological Hypertrophy Through Regulating Mitochondrial Dynamics by Le, Van, Murphy, Jiayuan, Fedorova, Julia, Bates, Lauryn, Yang, Yi, Davitt, Kayla, Logan, Cole, Ren, Di, Li, Ji

“…IntroductionSirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide-dependent histone deacetylase. We revealed that the pressure-overload-induced SIRT1 can…”
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Abstract 12111: Metformin Maintains Mitochondrial Integrity and Preserve Heart From Ischemia Reperfusion Injury Through Sestrin2-AMPK Signaling by Bates, Lauryn, Fedorova, Julia, Le, Van, Yang, Yi, Murphy, Jiayuan, Davitt, Kayla, Logan, Cole, Ren, Di, Li, Ji

“…IntroductionMetformin activates AMP-activated protein kinase (AMPK) to improve cardiac function during ischemia and reperfusion (I/R). We reported that…”
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Decreased excitability of leptin-sensitive anterior insula pyramidal neurons in a rat model of compulsive food demand by Kirson, Dean, Spierling Bagsic, Samantha R., Murphy, Jiayuan, Chang, Hang, Vlkolinsky, Roman, Pucci, Sarah N., Prinzi, Julia, Williams, Casey A., Fang, Savannah Y., Roberto, Marisa, Zorrilla, Eric P.

“…Compulsive eating is an overlapping construct with binge eating that shares many characteristics with substance use disorders. Compulsive eating may impact…”
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Behavioral Economic Analysis of Binge Eating in Female Rats; Glucocorticoid Receptor Expression Level in the Central Amygdala after Intermittent Access to Palatable Food by Murphy, Jiayuan L

“…Binge eating is characterized by eating a large amount of food within a short period of time with the feeling of loss of control. We applied the principles of…”
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