Search Results - "Murphy, Cheryl E"
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Potentiation of tumor responses to DNA damaging therapy by the selective ATR inhibitor VX-970
Published in Oncotarget (30-07-2014)“…Platinum-based DNA-damaging chemotherapy is standard-of-care for most patients with lung cancer but outcomes remain poor. This has been attributed, in part, to…”
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Quantitative analysis of cell signaling and drug action via mass spectrometry-based systems level phosphoproteomics
Published in Proteomics (Weinheim) (01-03-2009)“…Protein phosphorylation is a primary form of information transfer in cell signaling pathways and plays a crucial role in regulating biological responses…”
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Quantitative measurement of epidermal growth factor receptor–mitogen-activated protein kinase signal transduction using a nine-plex, peptide-based immunoassay
Published in Analytical biochemistry (15-04-2008)“…Aberrant epidermal growth factor receptor (EGFR, ErbB1) signaling is implicated in cell transformation, motility, and invasion in a variety of cell types, and…”
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