Search Results - "Muroni, Maria R"
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Histologic subtyping affecting outcome of triple negative breast cancer: a large Sardinian population-based analysis
Published in BMC cancer (02-06-2020)“…Triple Negative breast cancer (TNBC) includes a heterogeneous group of tumors with different clinico-pathological features, molecular alterations and treatment…”
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2
Preliminary Results of Feasibility and Acceptability of Self-Collection for Cervical Screening in Italian Women
Published in Pathogens (Basel) (01-09-2023)“…Background: Given the diagnostic accuracy of HPV-DNA tests in terms of self-collected samples, in order to implement self-sampling in cervical screening…”
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3
Dual-specificity phosphatase 1 ubiquitination in extracellular signal-regulated kinase-mediated control of growth in human hepatocellular carcinoma
Published in Cancer research (Chicago, Ill.) (01-06-2008)“…Sustained activation of extracellular signal-regulated kinase (ERK) has been detected previously in numerous tumors in the absence of RAS-activating mutations…”
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4
Ras‐driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control
Published in International journal of cancer (01-11-2008)“…Fast growth and deregulation of G1 and S phases characterize preneoplastic and neoplastic liver lesions of genetically susceptible F344 rats, whereas a G1‐S…”
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5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication
Published in Journal of hepatology (01-03-2001)“…5'-Methylthioadenosine (MTA), a product of S-adenosylmethionine (SAM) catabolism, could undergo oxidation by mono-oxygenases and auto-oxidation. MTA and SAM…”
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6
SKP2 and CKS1 Promote Degradation of Cell Cycle Regulators and Are Associated With Hepatocellular Carcinoma Prognosis
Published in Gastroenterology (New York, N.Y. 1943) (01-11-2009)“…Background & Aims The cell cycle regulators P21WAF1 , P27KIP1 , P57KIP2 , P130, RASSF1A, and FOXO1 are down-regulated during hepatocellular carcinoma (HCC)…”
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7
EGFR kinase-dependent and kinase-independent roles in clear cell renal cell carcinoma
Published in American journal of cancer research (01-01-2016)“…Epidermal growth factor receptor (EGFR) is associated with progression of many epithelial malignancies and represents a significant therapeutic target…”
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Altered methionine metabolism and global DNA methylation in liver cancer: Relationship with genomic instability and prognosis
Published in International journal of cancer (01-12-2007)“…Mounting evidence underlines the role of genomic hypomethylation in the generation of genomic instability (GI) and tumorigenesis, but whether DNA…”
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Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease
Published in Carcinogenesis (New York) (01-08-2008)“…Mounting evidence underlines the role of inducible nitric oxide synthase (iNOS) in hepatocellular carcinoma (HCC) development, but its functional interactions…”
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10
Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer
Published in Hepatology (Baltimore, Md.) (01-12-2005)“…Current evidence indicates that neoplastic nodules induced in liver of Brown Norway (BN) rats genetically resistant to hepatocarcinogenesis are not prone to…”
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The degradation of cell cycle regulators by SKP2/CKS1 ubiquitin ligase is genetically controlled in rodent liver cancer and contributes to determine the susceptibility to the disease
Published in International journal of cancer (01-03-2010)“…Previous work showed a genetic control of cell cycle deregulation during hepatocarcinogenesis. We now evaluated in preneoplastic lesions, dysplastic nodules…”
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Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells
Published in Carcinogenesis (New York) (01-03-2004)“…A number of genetic interactions are involved in the control of cell cycle, but their role and nature have not been completely clarified. The knowledge of the…”
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13
Cell cycle deregulation in liver lesions of rats with and without genetic predisposition to hepatocarcinogenesis
Published in Hepatology (Baltimore, Md.) (01-06-2002)“…Preneoplastic and neoplastic hepatocytes undergo c-Myc up-regulation and overgrowth in rats genetically susceptible to hepatocarcinogenesis, but not in…”
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Identification and chromosome mapping of loci predisposing to colorectal cancer that control Wnt/β-catenin pathway and progression of early lesions in the rat
Published in Carcinogenesis (New York) (01-11-2007)“…Sporadic colorectal cancer (CRC) is a major health concern worldwide. Epidemiologic evidence suggests a polygenic predisposition to CRC, but the genes…”
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15
Mapping a sex hormone-sensitive gene determining female resistance to liver carcinogenesis in a congenic F344.BN-Hcs4 rat
Published in Cancer research (Chicago, Ill.) (01-11-2006)“…Hepatocellular carcinoma (HCC) is prevalent in human and rodent males. Hepatocarcinogenesis is controlled by various genes in susceptible F344 and resistant…”
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Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-κB and Mat1A genes in the early stages of rat liver carcinogenesis
Published in Carcinogenesis (New York) (01-02-2005)“…Cell-cycle deregulation is an early event of hepatocarcinogenesis. We evaluated the role of changes in activity of nuclear factor κB (NF-κB) and some related…”
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Polygenic control of hepatocarcinogenesis in Copenhagen X F344 rats
Published in International journal of cancer (10-08-2004)“…Cop and CFF1 rats exhibit resistance to hepatocarcinogenesis, associated with high rates of remodeling of neoplastic lesions. We have mapped…”
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Role of HSP90, CDC37, and CRM1 as modulators of P16INK4A activity in rat liver carcinogenesis and human liver cancer
Published in Hepatology (Baltimore, Md.) (01-12-2005)Get full text
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Chromosome mapping of multiple loci affecting the genetic predisposition to rat liver carcinogenesis
Published in Cancer research (Chicago, Ill.) (01-08-2002)“…Previous studies on (BNxF344)F1 (BFF1) rat model of genetic predisposition to hepatocarcinogenesis led to the identification, in BFF1xF344 backcross progeny,…”
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Phenotypic reversion of rat neoplastic liver nodules is under genetic control
Published in International journal of cancer (20-05-2003)“…Low DNA synthesis and high redifferentiation (remodeling) characterize neoplastic nodules induced by chemical carcinogens in hybrid BFF1 rats, generated by…”
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