Search Results - "Muro, Shigeo"
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Efficacy of budesonide/glycopyrronium/formoterol metered dose inhaler in patients with COPD: post-hoc analysis from the KRONOS study excluding patients with airway reversibility and high eosinophil counts
Published in Respiratory research (28-06-2021)“…Abstract Background In the Phase III KRONOS study, triple therapy with budesonide/glycopyrronium/formoterol fumarate metered dose inhaler (BGF MDI) was shown…”
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Relationship Between Intermittent Hypoxia and Type 2 Diabetes in Sleep Apnea Syndrome
Published in International journal of molecular sciences (25-09-2019)“…Sleep apnea syndrome (SAS) is a very common disease involving intermittent hypoxia (IH), recurrent symptoms of deoxygenation during sleep, strong daytime…”
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Generation of Alveolar Epithelial Spheroids via Isolated Progenitor Cells from Human Pluripotent Stem Cells
Published in Stem cell reports (09-09-2014)“…No methods for isolating induced alveolar epithelial progenitor cells (AEPCs) from human embryonic stem cells (hESCs) and induced pluripotent stem cells…”
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Fraction of MHCII and EpCAM expression characterizes distal lung epithelial cells for alveolar type 2 cell isolation
Published in Respiratory research (07-08-2017)“…Alveolar type 2 (AT2) cells play important roles in maintaining adult lung homeostasis. AT2 cells isolated from the lung have revealed the cell-specific…”
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Benefits of budesonide/glycopyrronium/formoterol fumarate dihydrate on lung function and exacerbations of COPD: a post-hoc analysis of the KRONOS study by blood eosinophil level and exacerbation history
Published in Respiratory research (05-08-2024)“…Japanese guidelines recommend triple inhaled corticosteroid (ICS)/long-acting muscarinic antagonist (LAMA)/long-acting β -agonist (LABA) therapy in patients…”
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CT scan findings of emphysema predict mortality in COPD
Published in Chest (01-09-2010)“…Emphysematous change as assessed by CT imaging has been reported to correlate with COPD prognostic factors such as FEV(1) and diffusing capacity of the lung…”
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Directed Induction of Functional Multi-ciliated Cells in Proximal Airway Epithelial Spheroids from Human Pluripotent Stem Cells
Published in Stem cell reports (12-01-2016)“…Multi-ciliated airway cells (MCACs) play a role in mucociliary clearance of the lung. However, the efficient induction of functional MCACs from human…”
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Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory cell and molecular biology (01-07-2020)“…Epithelial dysfunction in the small airways may cause the development of emphysema in chronic obstructive pulmonary disease. C/EBPα (CCAAT/enhancer binding…”
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Investigation of time profile of FEV1 across the onset of potential COPD: a retrospective cohort study using medical checkup data in Japan
Published in Scientific reports (03-04-2023)“…This study compared the time profile of FEV 1 after COPD diagnosis among rapid decliners, slow decliners, and sustainers in the year of COPD diagnosis. COPD…”
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Angiopoietin-like 4 is a critical regulator of fibroblasts during pulmonary fibrosis development
Published in American journal of respiratory cell and molecular biology (01-09-2023)“…Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible interstitial pneumonia caused by the excessive production and deposition of…”
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Changes in mortality among patients with chronic obstructive pulmonary disease from the 1990s to the 2000s: a pooled analysis of two prospective cohort studies
Published in BMJ open (07-03-2023)“…ObjectivesThis study aimed to identify and investigate changes in the mortality of patients with chronic obstructive pulmonary disease (COPD) at the same…”
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A Rare Case of Overlapping Durvalumab-induced Myositis, Takotsubo-like Morphological Changes Caused by Myocarditis, and Myasthenia Gravis
Published in Internal Medicine (2024)“…Immune checkpoint inhibitors can cause a range of immune-related adverse events, including myositis, Takotsubo cardiomyopathy, and myasthenia gravis. We herein…”
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Real-world effectiveness of early intervention with fixed-dose tiotropium/olodaterol vs tiotropium in Japanese patients with COPD: a high-dimensional propensity score–matched cohort analysis
Published in Respiratory research (17-06-2021)“…Abstract Background Escalation to triple therapy (long-acting muscarinic antagonist/β 2 -agonist, inhaled corticosteroid [ICS]) in chronic obstructive…”
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Statement from the Japanese Respiratory Society: Working diagnosis and initial management of COPD during the COVID-19 pandemic
Published in Respiratory investigation (01-07-2021)“…The Japanese Respiratory Society (JRS) has recommended spirometry for the diagnosis of respiratory diseases. It is indispensable for the confirmation of…”
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Associations of airway tree to lung volume ratio on computed tomography with lung function and symptoms in chronic obstructive pulmonary disease
Published in Respiratory research (18-04-2019)“…Decreased airway lumen size and increased lung volume are major structural changes in chronic obstructive pulmonary disease (COPD). However, even though the…”
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Survival impact of treatment for chronic obstructive pulmonary disease in patients with advanced non-small-cell lung cancer
Published in Scientific reports (08-12-2021)“…Chronic obstructive pulmonary disease (COPD) may coexist with lung cancer, but the impact on prognosis is uncertain. Moreover, it is unclear whether…”
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Desaturation during the stair-climbing test for patients who will undergo pulmonary resection: an indicator of postoperative complications
Published in General thoracic and cardiovascular surgery (01-01-2020)“…Objective It is widely accepted that exercise tolerance tests are applicable in perioperative risk assessment for patients who undergo pulmonary resection;…”
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Emphysema detected on computed tomography and risk of lung cancer: A systematic review and meta-analysis
Published in Lung cancer (Amsterdam, Netherlands) (01-07-2012)“…Abstract Background Studies exploring the association between emphysema detected on chest computed tomography (CT) and lung cancer have yielded mixed results…”
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Recurrence of sarcoidosis accompanied by lung cancer after drug-induced pulmonary sarcoidosis with lung injury
Published in Respirology case reports (01-04-2024)“…Sarcoidosis is a multisystemic granulomatous disease that is frequently localized in the lungs and lymph nodes. We herein report a case of pulmonary…”
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