Search Results - "Muro, Enrique M."

The distributions of protein coding genes within chromatin domains in relation to human disease by Muro, Enrique M, Ibn-Salem, Jonas, Andrade-Navarro, Miguel A

“…Our understanding of the nuclear chromatin structure has increased hugely during the last years mainly as a consequence of the advances in chromatin…”
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Gene function in early mouse embryonic stem cell differentiation by Hailesellasse Sene, Kagnew, Porter, Christopher J, Palidwor, Gareth, Perez-Iratxeta, Carolina, Muro, Enrique M, Campbell, Pearl A, Rudnicki, Michael A, Andrade-Navarro, Miguel A

“…Little is known about the genes that drive embryonic stem cell differentiation. However, such knowledge is necessary if we are to exploit the therapeutic…”
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Pseudogenes as an alternative source of natural antisense transcripts by Muro, Enrique M, Andrade-Navarro, Miguel A

“…Naturally occurring antisense transcripts (NATs) are non-coding RNAs that may regulate the activity of sense transcripts to which they bind because of…”
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RNA Sequencing of Human Peripheral Blood Cells Indicates Upregulation of Immune-Related Genes in Huntington's Disease by Andrade-Navarro, Miguel A, Mühlenberg, Katja, Spruth, Eike J, Mah, Nancy, González-López, Adrián, Andreani, Tommaso, Russ, Jenny, Huska, Matthew R, Muro, Enrique M, Fontaine, Jean-Fred, Amstislavskiy, Vyacheslav, Soldatov, Alexei, Nietfeld, Wilfried, Wanker, Erich E, Priller, Josef

“…Huntington's disease (HD) is an autosomal dominantly inherited neurodegenerative disorder caused by a trinucleotide repeat expansion in the gene. As…”
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DiseaseLinc: Disease Enrichment Analysis of Sets of Differentially Expressed LincRNAs by More, Piyush, Talyan, Sweta, Fontaine, Jean-Fred, Muro, Enrique M, Andrade-Navarro, Miguel A

“…Long intergenic non-coding RNAs (LincRNAs) are long RNAs that do not encode proteins. Functional evidence is lacking for most of them. Their biogenesis is not…”
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Co-regulation of paralog genes in the three-dimensional chromatin architecture by Ibn-Salem, Jonas, Muro, Enrique M, Andrade-Navarro, Miguel A

“…Paralog genes arise from gene duplication events during evolution, which often lead to similar proteins that cooperate in common pathways and in protein…”
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Identification of transcribed protein coding sequence remnants within lincRNAs by Talyan, Sweta, Andrade-Navarro, Miguel A, Muro, Enrique M

“…Abstract Long intergenic non-coding RNAs (lincRNAs) are non-coding transcripts >200 nucleotides long that do not overlap protein-coding sequences. Importantly,…”
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Integration of expressed sequence tag data flanking predicted RNA secondary structures facilitates novel non-coding RNA discovery by Krzyzanowski, Paul M, Price, Feodor D, Muro, Enrique M, Rudnicki, Michael A, Andrade-Navarro, Miguel A

“…Many computational methods have been used to predict novel non-coding RNAs (ncRNAs), but none, to our knowledge, have explicitly investigated the impact of…”
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Identification of gene 3' ends by automated EST cluster analysis by Muro, Enrique M, Herrington, Robert, Janmohamed, Salima, Frelin, Catherine, Andrade-Navarro, Miguel A, Iscove, Norman N

“…The properties and biology of mRNA transcripts can be affected profoundly by the choice of alternative polyadenylation sites, making definition of the 3' ends…”
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Functional evidence of post-transcriptional regulation by pseudogenes by Muro, Enrique M., Mah, Nancy, Andrade-Navarro, Miguel A.

“…Pseudogenes have been mainly considered as functionless evolutionary relics since their discovery in 1977. However, multiple mechanisms of pseudogene…”
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ChIP on SNP-chip for genome-wide analysis of human histone H4 hyperacetylation by McCann, Jennifer A, Muro, Enrique M, Palmer, Claire, Palidwor, Gareth, Porter, Christopher J, Andrade-Navarro, Miguel A, Rudnicki, Michael A

“…SNP microarrays are designed to genotype Single Nucleotide Polymorphisms (SNPs). These microarrays report hybridization of DNA fragments and therefore can be…”
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Recent developments in StemBase: a tool to study gene expression in human and murine stem cells by Sandie, Reatha, Palidwor, Gareth A, Huska, Matthew R, Porter, Christopher J, Krzyzanowski, Paul M, Muro, Enrique M, Perez-Iratxeta, Carolina, Andrade-Navarro, Miguel A

“…Currently one of the largest online repositories for human and mouse stem cell gene expression data, StemBase was first designed as a simple web-interface to…”
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A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses by de Oliveira, Kivia A P, Kaergel, Eva, Heinig, Matthias, Fontaine, Jean-Fred, Patone, Giannino, Muro, Enrique M, Mathas, Stephan, Hummel, Michael, Andrade-Navarro, Miguel A, Hübner, Norbert, Scheidereit, Claus

“…NF-κB is widely involved in lymphoid malignancies; however, the functional roles and specific transcriptomes of NF-κB dimers with distinct subunit compositions…”
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Amplification of the Gene Ontology annotation of Affymetrix probe sets by Muro, Enrique M, Perez-Iratxeta, Carolina, Andrade-Navarro, Miguel A

“…The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but…”
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The pseudogenes of Mycobacterium leprae reveal the functional relevance of gene order within operons by Muro, Enrique M, Mah, Nancy, Moreno-Hagelsieb, Gabriel, Andrade-Navarro, Miguel A

“…Almost 50 years following the discovery of the prokaryotic operon, the functional relevance of gene order within operons remains unclear. In this work, we take…”
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Computational approaches to discovering noncoding RNA by Krzyzanowski, Paul M., Muro, Enrique M., Andrade-Navarro, Miguel A.

“…New developments are being brought to the field of molecular biology with the mounting evidence that RNA transcripts not translated into protein (noncoding…”
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MedlineRanker: flexible ranking of biomedical literature by Fontaine, Jean-Fred, Barbosa-Silva, Adriano, Schaefer, Martin, Huska, Matthew R, Muro, Enrique M, Andrade-Navarro, Miguel A

“…The biomedical literature is represented by millions of abstracts available in the Medline database. These abstracts can be queried with the PubMed interface,…”
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Study of stem cell function using microarray experiments by Perez-Iratxeta, Carolina, Palidwor, Gareth, Porter, Christopher J., Sanche, Neal A., Huska, Matthew R., Suomela, Brian P., Muro, Enrique M., Krzyzanowski, Paul M., Hughes, Evan, Campbell, Pearl A., Rudnicki, Michael A., Andrade, Miguel A.

“…DNA Microarrays are used to simultaneously measure the levels of thousands of mRNAs in a sample. We illustrate here that a collection of such measurements in…”
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StemBase: a resource for the analysis of stem cell gene expression data by Porter, Christopher J, Palidwor, Gareth A, Sandie, Reatha, Krzyzanowski, Paul M, Muro, Enrique M, Perez-Iratxeta, Carolina, Andrade-Navarro, Miguel A

“…StemBase is a database of gene expression data obtained from stem cells and derivatives mainly from mouse and human using DNA microarrays and Serial Analysis…”
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Simulation of plasticity in the adult visual cortex by Andrade, M A, Muro, E M, Morán, F

“…Retinal plasticity has been shown in the adult visual nervous system in mammals. Following a retinal lesion (scotoma) there is a reorganization of the cortical…”
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