Search Results - "Murnane, Robert"
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Ascending Reproductive Tract Infection in Pig-Tailed Macaques Inoculated with Mycoplasma genitalium
Published in Infection and immunity (16-06-2022)“…Mycoplasma genitalium is a sexually transmitted bacterial pathogen that causes urogenital disease in men and women. M. genitalium infections can persist for…”
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2
Anti-PD-1 chimeric antigen receptor T cells efficiently target SIV-infected CD4+ T cells in germinal centers
Published in The Journal of clinical investigation (01-04-2024)“…Programmed cell death protein 1 (PD-1) is an immune checkpoint marker commonly expressed on memory T cells and enriched in latently HIV-infected CD4+ T cells…”
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3
Evidence for persistence of the SHIV reservoir early after MHC haploidentical hematopoietic stem cell transplantation
Published in Nature communications (25-10-2018)“…Allogeneic transplantation (allo-HCT) has led to the cure of HIV in one individual, raising the question of whether transplantation can eradicate the HIV…”
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4
Macaque homologs of EBV and KSHV show uniquely different associations with simian AIDS-related lymphomas
Published in PLoS pathogens (01-10-2012)“…Two gammaherpesviruses, Epstein-Barr virus (EBV) (Lymphocryptovirus genus) and Kaposi's sarcoma-associated herpesvirus (KSHV) (Rhadinovirus genus) have been…”
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5
Gene Transfer in Adeno-Associated Virus Seropositive Rhesus Macaques Following Rapamycin Treatment and Subcutaneous Delivery of AAV6, but Not Retargeted AAV6 Vectors
Published in Human gene therapy (01-01-2021)“…Adeno-associated virus (AAV) vectors such as AAV6, which shows tropism for primary human CD4 T cells , are being explored for delivery of anti-HIV therapeutic…”
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6
Multigenic DNA vaccine induces protective cross-reactive T cell responses against heterologous influenza virus in nonhuman primates
Published in PloS one (21-12-2017)“…Recent avian and swine-origin influenza virus outbreaks illustrate the ongoing threat of influenza pandemics. We investigated immunogenicity and protective…”
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Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation
Published in PloS one (06-06-2018)“…A critical issue in transgene delivery studies is immune reactivity to the transgene- encoded protein and its impact on sustained gene expression. Here, we…”
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Autologous, Gene-Modified Hematopoietic Stem and Progenitor Cells Repopulate the Central Nervous System with Distinct Clonal Variants
Published in Stem cell reports (09-07-2019)“…Myeloid-differentiated hematopoietic stem cells (HSCs) have contributed to a number of novel treatment approaches for lysosomal storage diseases of the central…”
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Correction: Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation
Published in PloS one (01-11-2018)“…[This corrects the article DOI: 10.1371/journal.pone.0198154.]…”
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Morphine Produces Immunosuppressive Effects in Nonhuman Primates at the Proteomic and Cellular Levels
Published in Molecular & cellular proteomics (01-09-2012)“…Morphine has long been known to have immunosuppressive properties in vivo, but the molecular and immunologic changes induced by it are incompletely understood…”
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Evaluation of the immunogenicity and efficacy of an rVSV vaccine against Zika virus infection in macaca nemestrina
Published in Frontiers in virology (online) (01-01-2023)“…Zika virus (ZIKV) is a mosquito-borne flavivirus that causes an acute febrile illness. ZIKV can be transmitted between sexual partners and from mother to…”
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12
A multiplexed barcode approach to simultaneously evaluate gene delivery by adeno-associated virus capsid variants in nonhuman primates
Published in Hepatology communications (01-02-2023)“…Adeno-associated virus (AAV) vectors are widely used to deliver therapeutic transgenes to distinct tissues, including the liver. Vectors based on naturally…”
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13
Systemic Inflammatory Response Syndrome in Nonhuman Primates Culminating in Multiple Organ Failure, Acute Lung Injury, and Disseminated Intravascular Coagulation
Published in Toxicologic pathology (01-10-2009)“…The systemic inflammatory response syndrome (SIRS) is a clinicopathological manifestation of overexuberant acute-phase inflammation caused by infectious or…”
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Loss of immune homeostasis dictates SHIV rebound after stem-cell transplantation
Published in JCI insight (23-02-2017)“…The conditioning regimen used as part of the Berlin patient's hematopoietic cell transplant likely contributed to his eradication of HIV infection. We studied…”
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15
Oral Squamous Cell Carcinoma in a Pigtailed Macaque (Macaca nemestrina)
Published in Comparative medicine (01-06-2014)“…An adult, gravid, female pigtailed macaque (Macaca nemestrina) presented for facial swelling centered on the left mandible that was approximately 5 cm wide…”
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Transmission of Chagas Disease via Blood Transfusions in 2 Immunosuppressed Pigtailed Macaques (Macaca nemestrina)
Published in Comparative medicine (01-02-2014)“…A 2.25-y-old male pigtailed macaque (Macaca nemestrina) was experimentally irradiated and received a bone marrow transplant. After transplantation and…”
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Pulmonary Embolization of Fat and Bone Marrow in Cynomolgus Macaques (Macaca fascicularis)
Published in Comparative medicine (01-02-2011)“…Fat embolization (FE), the introduction of bone marrow elements into circulation, is a known complication of bone fractures. Although FE has been described in…”
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Primary hepatic Mycobacterium tuberculosis complex infection with terminal dissemination in a pig-tailed macaque (Macaca nemestrina)
Published in Journal of the American Association for Laboratory Animal Science (01-03-2011)“…An adult, female, pig-tailed macaque (Macaca nemestrina) of Indonesian origin presented with profound weight loss, anemia (PCV, 29%; normal, 36% to 45%),…”
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Dissertation Project for the Forensic Science Laboratory: Birch Reduction of Ephedrine and Analysis of Byproducts of Forensic Science Interest
Published in Journal of chemical education (11-05-2021)“…This undergraduate dissertation project was designed to enhance organic and analytical chemistry skills of final year forensic science students. A modified…”
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Paratuberculosis in a mandrill (Papio sphinx)
Published in Journal of veterinary diagnostic investigation (01-07-2002)“…Zoological Pathology Program, University of Illinois College of Veterinary Medicine, Loyola University Medical Center, Maywood, IL 60153, USA. A 2.5-year-old…”
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