Search Results - "Murnane, Pamela M."
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Evaluation of person-centered interventions to eliminate perinatal HIV transmission in Kisumu County, Kenya: A repeated cross-sectional study using aggregated registry data
Published in PLoS medicine (15-08-2024)“…Following a decline in perinatal HIV transmission from 20% to 10% between 2010 and 2017 in Kenya, rates have since plateaued with an estimated 8% transmission…”
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Achieving UNAIDS 90-90-90 targets for pregnant and postpartum women in sub-Saharan Africa: progress, gaps and research needs
Published in Journal of Virus Eradication (15-11-2018)“…The implementation of the 2013 World Health Organization Option B+ recommendations for HIV treatment during pregnancy has helped drive significant progress in…”
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Associations Between Anabolic-Androgenic Steroid Use and Sexual Health Behaviors Among Adolescent Boys: Results From the 2019 Youth Risk Behavior Survey
Published in American journal of men's health (01-07-2022)“…The aim of this study was to determine the association between lifetime anabolic-androgenic steroid (AAS) use and seven indicators of sexual health behaviors…”
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Geographic mobility and HIV care engagement among people living with HIV in rural Kenya and Uganda
Published in Tropical medicine and infectious disease (01-11-2023)“…Introduction: Human mobility is a critical aspect of existence and survival, but May compromise care engagement among people living with HIV (PLHIV). We…”
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Household-based HIV counseling and testing as a platform for referral to HIV care and medical male circumcision in Uganda: a pilot evaluation
Published in PloS one (13-12-2012)“…Combination HIV prevention initiatives incorporate evidence-based, biomedical and behavioral interventions appropriate and acceptable to specific populations,…”
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Initiation of antiretroviral therapy and viral suppression after home HIV testing and counselling in KwaZulu-Natal, South Africa, and Mbarara district, Uganda: a prospective, observational intervention study
Published in The lancet HIV (01-11-2014)“…Summary Background Antiretroviral therapy significantly decreases HIV-associated morbidity, mortality, and HIV transmission through HIV viral load suppression…”
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Estimating PMTCT's Impact on Heterosexual HIV Transmission: A Mathematical Modeling Analysis
Published in PloS one (11-08-2015)“…Prevention of mother-to-child HIV transmission (PMTCT) strategies include combined short-course antiretrovirals during pregnancy (Option A), triple-drug…”
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Modeling HIV disease progression and transmission at population-level: The potential impact of modifying disease progression in HIV treatment programs
Published in Epidemics (01-06-2018)“…Mathematical models that incorporate HIV disease progression dynamics can estimate the potential impact of strategies that delay HIV disease progression and…”
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First cases of SARS-CoV-2 infection and secondary transmission in Kisumu, Kenya
Published in PLOS global public health (2022)“…We investigated the first 152 laboratory-confirmed SARS-CoV-2 cases (125 primary and 27 secondary) and their 248 close contacts in Kisumu County, Kenya…”
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Using plasma viral load to guide antiretroviral therapy initiation to prevent HIV-1 transmission
Published in PloS one (30-11-2012)“…Current WHO guidelines recommend antiretroviral therapy (ART) initiation at CD4 counts ≤350 cells/µL. Increasing this threshold has been proposed, with a…”
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Performance-Enhancing Substance Use and Sexual Risk Behaviors among U.S. Men: Results from a Prospective Cohort Study
Published in The Journal of sex research (24-07-2022)“…Performance-enhancing substance (PES) use is common among young men and prior research has documented cross-sectional associations between anabolic-androgenic…”
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High HIV Testing Uptake and Linkage to Care in a Novel Program of Home-Based HIV Counseling and Testing With Facilitated Referral in KwaZulu-Natal, South Africa
Published in Journal of acquired immune deficiency syndromes (1999) (01-09-2013)“…OBJECTIVE:For antiretroviral therapy (ART) to have a population-level HIV prevention impact, high levels of HIV testing and effective linkages to HIV care…”
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Efficacy of preexposure prophylaxis for HIV-1 prevention among high-risk heterosexuals: subgroup analyses from a randomized trial
Published in AIDS (London) (24-08-2013)“…Daily oral antiretroviral preexposure prophylaxis (PrEP) is a promising strategy for prevention of HIV-1 acquisition. Three clinical trials demonstrated PrEP…”
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Hair levels of preexposure prophylaxis drugs measure adherence and are associated with renal decline among men/transwomen
Published in AIDS (London) (23-10-2017)“…The US preexposure prophylaxis (PrEP) Demonstration Project (U.S. Demo) evaluated MSM on PrEP postmarketing and found low seroconversion rates. The objective…”
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Switching to Efavirenz Versus Remaining on Ritonavir-boosted Lopinavir in Human Immunodeficiency Virus-infected Children Exposed to Nevirapine: Long-term Outcomes of a Randomized Trial
Published in Clinical infectious diseases (01-08-2017)“…Background. We previously demonstrated the noninferiority of switching to efavirenz (EFV) versus remaining on ritonavir-boosted lopinavir (LPV/r) for virologic…”
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Distinct forms of migration and mobility are differentially associated with HIV treatment adherence
Published in AIDS (London) (01-06-2022)“…We examined whether human mobility was associated with antiretroviral treatment adherence, measured via antiretroviral hair concentrations. This is a…”
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Factors associated with phosphatidylethanol (PEth) sensitivity for detecting unhealthy alcohol use: An individual patient data meta‐analysis
Published in Alcoholism, clinical and experimental research (01-06-2021)“…Background Objective measurement of alcohol consumption is important for clinical care and research. Adjusting for self‐reported alcohol use, we conducted an…”
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Disclosure to South African children about their own HIV status over time
Published in AIDS care (04-03-2023)“…Disclosure to children living with HIV (CLHIV) about their own status is associated with positive outcomes such as treatment adherence, but prior…”
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Using phosphatidylethanol as an adjunct to self-reported alcohol use improves identification of liver fibrosis risk
Published in The American journal of gastroenterology (31-10-2024)“…Accurate assessment of alcohol use informs prevention and management of liver disease. We examined whether phosphatidylethanol (PEth, an alcohol metabolite)…”
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Antiretroviral Therapy Adherence During and Postbreastfeeding Cessation Measured by Tenofovir Levels in Hair
Published in Journal of acquired immune deficiency syndromes (1999) (01-11-2022)“…We examined change in antiretroviral treatment (ART) adherence after breastfeeding (BF) cessation using hair tenofovir (TFV) concentrations as an objective…”
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