Search Results - "Murnane, J M"

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  1. 1

    Alterations in cathepsin H activity and protein patterns in human colorectal carcinomas by DEL RE, E. C, SHUJA, S, CAI, J, MURNANE, M. J

    Published in British journal of cancer (01-04-2000)
    “…Our analyses of cathepsin H activity levels and protein forms in human colorectal cancers compared to matched control mucosa support the concept that altered…”
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  2. 2

    Presence of activated ras correlates with increased cysteine proteinase activities in human colorectal carcinomas by Kim, Kwonseop, Cai, Jinguo, Shuja, Sania, Kuo, Tom, Murnane, Mary Jo

    Published in International journal of cancer (21-08-1998)
    “…The metastatic potential of ras‐transfected cells has been attributed in part to significant ras induction of proteinase expression. To determine whether…”
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  3. 3

    Marked increases in cathepsin B and L activities distinguish papillary carcinoma of the thyroid from normal thyroid or thyroid with non‐neoplastic disease by Shuja, Sania, Murnane, Mary Jo

    Published in International journal of cancer (16-05-1996)
    “…Cathepsin B (CB) and cathepsin L (CL) are cysteine endopeptidases involved in the processing of thyroglobulin (Tg) in the normal thyroid. As thyroglobulin…”
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  4. 4

    Stage-specific increases in cathepsin B messenger RNA content in human colorectal carcinoma by MURNANE, M. J, SHEAHAN, K, OZDEMIRLI, M, SHUJA, S

    Published in Cancer research (Chicago, Ill.) (15-02-1991)
    “…Cathepsin B mRNA levels and banding patterns were characterized in human colorectal mucosa and carcinoma tissues from patients with tumors of different Dukes'…”
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  5. 5

    Cysteine protease activities and tumor development in human colorectal carcinoma by SHEAHAN, K, SHUJA, S, MURNANE, M. J

    Published in Cancer research (Chicago, Ill.) (15-07-1989)
    “…Many studies of malignant cells or tissues in culture have implicated cysteine proteases in the progression of malignancy. We have extended these observations…”
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  6. 6

    Cysteine endopeptidase activity levels in normal human tissues, colorectal adenomas and carcinomas by Shuja, S, Sheahan, K, Murnane, M J

    Published in International journal of cancer (30-09-1991)
    “…We have assayed cysteine endopeptidase activities in 17 types of normal human tissue and in matched sets of colorectal mucosa, adenoma and carcinoma samples…”
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  7. 7

    Cathepsin B activity and protein levels in thyroid carcinoma, Graves' disease, and multinodular goiters by Shuja, S, Cai, J, Iacobuzio-Donahue, C, Zacks, J, Beazley, R M, Kasznica, J M, O'Hara, C J, Heimann, R, Murnane, M J

    Published in Thyroid (New York, N.Y.) (01-06-1999)
    “…Cathepsin B (CB) is involved in the hydrolysis of thyroglobulin (Tg) and thought to be regulated by thyroid stimulating hormone (TSH) in the normal thyroid…”
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  8. 8

    N‐ras protein: Frequent quantitative and qualitative changes occur in human colorectal carcinomas by Kim, Kwonseop, Kuo, Tom, Cai, Jinguo, Shuja, Sania, Murnane, Mary Jo

    Published in International journal of cancer (29-05-1997)
    “…Point mutation and overexpression are recognized mechanisms for ras activation in malignancy. However, little information is available on overexpression of…”
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  9. 9

    Embryonic--Fetal Erythroid Characteristics of a Human Leukemic Cell Line by Benz, Edward J., Murnane, Mary J., Tonkonow, Barry L., Berman, Brian W., Mazur, Eric M., Cavallesco, Cesira, Jenko, Trina, Snyder, Edwin L., Forget, Bernard G., Hoffman, Ronald

    “…We have studied a number of cell surface, enzyme, and protein markers in the human leukemic K562 cell line. We have confirmed previous observations that these…”
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  10. 10

    Human cathepsin B-encoding cDNAs: sequence variations in the 3'-untranslated region by Tam, S W, Cote-Paulino, L R, Peak, D A, Sheahan, K, Murnane, M J

    Published in Gene (25-02-1994)
    “…We have isolated two cathepsin B (CTSB)-encoding cDNAs, hCBF1 and hCBF2, from a normal human embryonic fibroblast library. These clones demonstrate 98%…”
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  11. 11

    Expression and induction of cathepsins B and D in K562 cells by Murnane, M J, Phipps, P M, Denekamp, D S

    Published in Experimental hematology (01-01-1988)
    “…Three distinct lysosomal protease activities have been identified in the human leukemia cell line, K562. These include cathepsin D, the classic protease of the…”
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  12. 12

    Chloride transport properties of human leukemic cell lines K562 and HL60 by Dissing, S, Hoffman, R, Murnane, M J, Hoffman, J F

    Published in The American journal of physiology (01-07-1984)
    “…The Cl- transport characteristics of the human leukemic cell lines K562 and HL60, with erythroid and granulocytic phenotypic features, respectively, were…”
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  13. 13

    Studies of BFU-E in flask cultures of human peripheral and cord blood cells by Murnane, M J, Hoffman, R

    “…Early erythroid progenitors (the burst-forming units-erythroid or BFU-E) from human peripheral and cord blood mononuclear cells were maintained in flask…”
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  14. 14

    Glucoprivic feeding is impaired by lateral or fourth ventricular alloxan injection by Ritter, S, Murnane, J M, Ladenheim, E E

    Published in The American journal of physiology (01-09-1982)
    “…Feeding and blood glucose responses to insulin and 2-deoxy-D-glucose (2-DG) were examined in rats previously given lateral or fourth ventricular injections of…”
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  15. 15

    Tay-Sachs' and Sandhoff's Diseases: The Assignment of Genes for Hexosaminidase A and B to Individual Human Chromosomes by Gilbert, F., Kucherlapati, R., Creagan, R. P., Murnane, M. J., Darlington, G. J., Ruddle, F. H.

    “…The techniques of somatic cell genetics have been used to establish the linkage relationships of loci coding for two forms (A and B) of hexosaminidase (EC…”
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  16. 16

    Intraventricular alloxan impairs feeding to both central and systemic glucoprivation by Murnane, J M, Ritter, S

    Published in Physiology & behavior (01-04-1985)
    “…Fourth ventricular alloxan injections impair the feeding response to systemically induced glucoprivation. However, the effect of alloxan on responses to…”
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  17. 17

    Elevations in Cathepsin B Protein Content and Enzyme Activity Occur Independently of Glycosylation during Colorectal Tumor Progression by Iacobuzio-Donahue, Christine A., Shuja, Sania, Cai, Jinguo, Peng, Phyllis, Murnane, Mary Jo

    Published in The Journal of biological chemistry (14-11-1997)
    “…Western blots, enzyme assays, protein glycosylation studies, and immunohistochemical staining were used to characterize cathepsin B expression at successive…”
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  18. 18

    Hemin Control of Heme Biosynthesis and Catabolism in a Human Leukemia Cell Line by Hoffman, Ronald, Ibrahim, Nader, Murnane, Mary Jo, Diamond, Ann, Forget, Bernard G., Levere, Richard D.

    Published in Blood (01-09-1980)
    “…Hemin treatment of the Philadelphia chromosome positive leukemia cell line, K562, accentuates a number of erythroid phenotypic characteristics. The nature of…”
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  19. 19

    Alloxan-induced glucoprivic feeding deficits are blocked by D-glucose and amygdalin by Murnane, J M, Ritter, S

    Published in Pharmacology, biochemistry and behavior (01-01-1985)
    “…Intracerebroventricular injection of alloxan, a pancreatic beta (B) cell cytotoxin, impairs glucoprivic feeding in rats. The goal of this experiment was to…”
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  20. 20

    Induction of Erythropoietic Colonies in a Human Chronic Myelogenous Leukemia Cell Line by Hoffman, Ronald, Murnane, Mary Jo, Benz, Edward J., Prohaska, Rainer, Floyd, Victoria, Dainiak, Nicholas, Forget, Bernard G., Furthmayr, Heinz

    Published in Blood (01-11-1979)
    “…The ability of cells derived from the K562 cell line to generate erythropoietic colonies was studied. The K562 cell line was derived from a patient with…”
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