Search Results - "Murley, Andrew"
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Determinants and Functions of Mitochondrial Behavior
Published in Annual review of cell and developmental biology (01-01-2014)“…Mitochondria are ancient organelles evolved from bacteria. Over the course of evolution, the behavior of mitochondria inside eukaryotic cells has changed…”
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Ltc1 is an ER-localized sterol transporter and a component of ER-mitochondria and ER-vacuole contacts
Published in The Journal of cell biology (25-05-2015)“…Organelle contact sites perform fundamental functions in cells, including lipid and ion homeostasis, membrane dynamics, and signaling. Using a forward…”
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Endoplasmic reticulum-associated mitochondria–cortex tether functions in the distribution and inheritance of mitochondria
Published in Proceedings of the National Academy of Sciences - PNAS (05-02-2013)“…To elucidate the functional roles of mitochondrial dynamics in vivo, we identified genes that become essential in cells lacking the dynamin-related proteins…”
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Sterol transporters at membrane contact sites regulate TORC1 and TORC2 signaling
Published in The Journal of cell biology (04-09-2017)“…Membrane contact sites (MCSs) function to facilitate the formation of membrane domains composed of specialized lipids, proteins, and nucleic acids. In cells,…”
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ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast
Published in eLife (14-05-2013)“…Mitochondrial division is important for mitochondrial distribution and function. Recent data have demonstrated that ER-mitochondria contacts mark mitochondrial…”
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Launching a saliva-based SARS-CoV-2 surveillance testing program on a university campus
Published in PloS one (26-05-2021)“…Regular surveillance testing of asymptomatic individuals for SARS-CoV-2 has been center to SARS-CoV-2 outbreak prevention on college and university campuses…”
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The Emerging Network of Mitochondria-Organelle Contacts
Published in Molecular cell (03-03-2016)“…Membrane contact sites between mitochondria and other organelles are important for lipid and ion exchange, membrane dynamics, and signaling. Recent advances…”
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Macroautophagy in quiescent and senescent cells: a pathway to longevity?
Published in Trends in cell biology (01-06-2023)“…Cellular quiescence – reversible exit from the cell cycle – is an important feature of many cell types important for organismal health. Aging and cellular…”
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Life in lockdown: Orchestrating endoplasmic reticulum and lysosome homeostasis for quiescent cells
Published in Molecular cell (06-10-2022)“…Cellular quiescence—reversible exit from the cell cycle—is an important feature of many cell types important for organismal health. Quiescent cells activate…”
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Discovery of sterol lipid transport proteins and their role in Target of Rapamycin signaling in Saccharomyces cerevisiae cells
Published 01-01-2016“…Organelle contact sites are regions where the membranes of two organelles are actively apposed at a distance of 10-30 nm by tethering proteins. Organelle…”
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Dissertation