Search Results - "Murineddu, G"

The novel cannabinoid antagonist SM-11 reduces hedonic aspect of food intake through a dopamine-dependent mechanism by Fois, G.R., Fattore, L., Murineddu, G., Salis, A., Pintore, G., Asproni, B., Pinna, G.A., Diana, M.

“…[Display omitted] Cannabinoids, endogenous and exogenously administered, are known to positively regulate food intake and energy balance. Since CB1 receptor…”
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Synthesis of biologically active bridged diazabicycloheptanes by Murineddu, G, Asproni, B, Pinna, G, Curzu, M M, Dore, A, Pau, A, Deligia, F, Pinna, G A

“…The chemistry underlying how diazabicycloheptanes are assembled is described, subdivided according to chemical structure of two types, the 3,6…”
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An overview on different classes of viral entry and respiratory syncitial virus (RSV) fusion inhibitors by Murineddu, G, Murruzzu, C, Pinna, G A

“…The therapeutic approach to AIDS is based on the combination of different drugs in the highly active antiretroviral therapy (HAART) regimen. These drugs have a…”
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Synthesis and Anti-HIV-1 Activity of New Delavirdine Analogues Carrying Arylpyrrole Moieties by PINNA, Gérard Aimè, LORIGA, Giovanni, MURINEDDU, Gabriele, GRELLA, Giuseppe, MURA, Massimo, VARGIU, Laura, MURGIONI, Chiara, COLLA, Paolo LA

“…In our search for novel anti-human immunodeficiency virus (HIV)-1 agents, 14 delavirdine analogues were synthesized and evaluated as potential anti-HIV-1…”
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Thienocinnolinone alkanoic acid derivatives as aldose reductase inhibitors by Pau, A, Asproni, B, Murineddu, G, Boatto, G, Grella, G E, Rakowitz, D, Costantino, L, Pinna, G A

“…A new series of 8-halogen-4,4a,5,6-tetrahydrothieno[2,3-h]cinnolinone-N2-alkanoic acids was prepared and tested for aldose reductase (ALR2) inhibitory…”
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Synthesis and cytotoxicity of substituted 2-benzylnaphth[2,3- d]imidazoles by Grella, G.E, Cabras, M.C, Murineddu, G, Pau, A, Pinna, G.A

“…Designed as a new series of so called “bivalent ligand” containing the proposed 2-benzylnaphthimidazole-type structure, a number of 2-benzylnaphth[2,3-…”
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Chiral pyridine N-oxides: useful ligands for asymmetric catalysis by Chelucci, Giorgio, Murineddu, Gabriele, Pinna, Gerard A

“…The synthesis and applications in asymmetric catalysis of chiral pyridine N-oxide derivatives such as 1– 3, is reviewed. The synthesis and applications in…”
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Preliminary Anti-Coxsackie Activity of Novel 1-[4-(5,6-dimethyl(H)- 1H(2H)-benzotriazol-1(2)-yl)phenyl]-3-alkyl(aryl)ureas by Piras, Sandra, Corona, Paola, Ibba, Roberta, Riu, Federico, Murineddu, Gabriele, Sanna, Giuseppina, Madeddu, Silvia, Delogu, Ilenia, Loddo, Roberta, Carta, Antonio

“…Coxsackievirus infections are associated with cases of aseptic meningitis, encephalitis, myocarditis, and some chronic disease. A series of…”
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Synthesis, modelling, and μ-opioid receptor affinity of N-3(9)-arylpropenyl- N-9(3)-propionyl-3,9-diazabicyclo[3.3.1]nonanes by Pinna, G.A, Murineddu, G, Curzu, M.M, Villa, S, Vianello, P, Borea, P.A, Gessi, S, Toma, L, Colombo, D, Cignarella, G

“…A series of N-3-arylpropenyl- N-9-propionyl-3,9-diazabicyclo[3.3.1]nonanes ( 1a–g) and of reverted N-3-propionyl- N-9-arylpropenyl isomers ( 2a–g), as…”
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Synthesis and cytotoxicity evaluation of thiophene analogues of 1-methyl-2,3-bis(hydroxymethyl)benzo[ g]indole bis[ N-(2-propyl)carbamate] by Pirisi, M.A, Murineddu, G, Mussinu, J.M, Pinna, G.A

“…The cytotoxicity of the bis[ N-(2-propyl)carbamates] 2 and 3 which are linked to thieno[ i, j- g]indole scaffolds through methylene bridges were studied as…”
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Tricyclic Pyrazoles. 3. Synthesis, Biological Evaluation, and Molecular Modeling of Analogues of the Cannabinoid Antagonist 8-Chloro-1-(2‘,4‘-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6- tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide by Murineddu, Gabriele, Ruiu, Stefania, Loriga, Giovanni, Manca, Ilaria, Lazzari, Paolo, Reali, Roberta, Pani, Luca, Toma, Lucio, Pinna, Gérard A

“…A series of analogues of 8-chloro-1-(2‘,4‘-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide 4a (NESS 0327)…”
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Tricyclic pyrazoles. Part 1: Synthesis and biological evaluation of novel 1,4-dihydroindeno[1,2-c]pyrazol-based ligands for CB1 and CB2 cannabinoid receptors by MUSSINU, Jean-Mario, RUIU, Stefania, MULE, Antonio C, PAU, Amedeo, CARAI, Mauro A. M, LORIGA, Giovanni, MURINEDDU, Gabriele, PINNA, Gérard A

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Editorial [hot topic: cannabinoid receptors ligands (guest editor: Gabriele Murineddu)] by Murineddu, G

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Synthesis and application in asymmetric copper(I)-catalyzed allylic oxidation of a new chiral 1,10-phenanthroline derived from pinene by Chelucci, Giorgio, Loriga, Giovanni, Murineddu, Gabriele, Pinna, Gerard A

“…A convenient and rapid method for the preparation of chiral C 2-symmetric 1,10-phenanthrolines is reported. As an example of this procedure the synthesis of…”
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Synthesis of 3,6-diazabicyclo[3.1.1]heptanes as novel ligands for the opioid receptors by Loriga, Giovanni, Manca, Ilaria, Murineddu, Gabriele, Chelucci, Giorgio, Villa, Stefania, Gessi, Stefania, Toma, Lucio, Cignarella, Giorgio, Pinna, Gerard A.

“…In an effort to improve diazabicycloalkane-based opioid receptor ligands, N-3(6)-arylpropenyl- N-6(3)-propionyl-3,6-diazabicyclo[3.1.1]heptanes ( 3A, Ba– i)…”
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Tricyclic Pyrazoles. 4. Synthesis and Biological Evaluation of Analogues of the Robust and Selective CB sub(2) Cannabinoid Ligand 1-(2',4'-Dichlorophenyl)-6-methyl-N-piperidin -1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide by Murineddu, G, Lazzari, P, Ruiu, S, Sanna, A, Loriga, G, Manca, I, Falzoi, M, Dessi, C, Curzu, M M, Chelucci, G, Pani, L, Pinna, G A

“…New analogues (2a-p) of the previously reported CB sub(2) ligands 6-methyl- and 6-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4-…”
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Design of a new class of chiral C 2 -symmetric dipyridylmethane ligands and their application in asymmetric catalysis by Chelucci, Giorgio, Loriga, Giovanni, Murineddu, Gabriele, Pinna, Gerard A.

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Synthesis of novel diazatricyclodecanes (DTDs). Effects of structural variation at the C3′ allyl end and at the phenyl ring of the cinnamyl chain on μ-receptor affinity and opioid antinociception by Pinna, Gérard Aimè, Cignarella, Giorgio, Ruiu, Stefania, Loriga, Giovanni, Murineddu, Gabriele, Villa, Stefania, Grella, Giuseppe Enrico, Cossu, Gregorio, Fratta, Walter

“…Two series of analogues of 9-propionyl-10-cinnamyl-9,10-diazatricyclo[4.2.1.1 2,5]decane ( 1a) and 2-propionyl-7-cinnamyl-2,7-diazatricyclo[4.4.0.0 3,8]decane…”
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Synthesis and analgesic-antiinflammatory activities of novel acylarylhydrazones with a 5-phenyl-4-R-3-pyrrolyl-acyl moiety by Murineddu, Gabriele, Loriga, Giovanni, Gavini, Elisabetta, Peana, Alessandra T., Mulè, Antonio C., Pinna, Gérard A.

“…A new series of arylidene 5‐phenyl‐4‐R‐pyrrole‐3‐carbohydrazides 1a—j were prepared and evaluated for their analgesic‐antiinflammatory activities. All…”
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N-3(9)-Arylpropenyl- N-9(3)-propionyl-3,9-diazabicyclo[3.3.1]nonanes as μ-Opioid receptor agonists. Effects on μ-Affinity of arylalkenyl chain modifications by Pinna, Gérard A., Cignarella, Giorgio, Loriga, Giovanni, Murineddu, Gabriele, Mussinu, Jean-Mario, Ruiu, Stefania, Fadda, Paola, Fratta, Walter

“…Two series of N-3-arylpropenyl- N-9-propionyl-3,9-diazabicyclo[3.3.1]nonanes ( 1b– j) and of the reverted N-3-propionyl- N-9-arylpropenyl isomers ( 2b– j) as…”
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