Search Results - "Murillo Garzón, Virginia"
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Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer
Published in Nature communications (01-05-2018)“…Wnt-11 promotes cancer cell migration and invasion independently of β-catenin but the receptors involved remain unknown. Here, we provide evidence that FZD 8…”
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WNT signalling in prostate cancer
Published in Nature reviews. Urology (01-11-2017)“…Key Points Genetic changes in APC and CTNNB1 , which activate canonical (β-catenin-dependent) WNT signalling, are observed in up to 22% of castration-resistant…”
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High-content screening of natural products reveals novel nuclear export inhibitors
Published in Journal of biomolecular screening (01-01-2014)“…Natural products are considered an extremely valuable source for the discovery of new drugs against diverse pathologies. As yet, we have only explored a…”
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4
Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1
Published in Oncogene (01-09-2018)“…Aberrant transforming growth factor–β (TGF-β) signaling is a hallmark of the stromal microenvironment in cancer. Dickkopf-3 (Dkk-3), shown to inhibit TGF-β…”
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