Search Results - "Murillo‐de‐Ozores, Adrián Rafael"
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Transient response of serpinA3 during cellular stress
Published in The FASEB journal (01-03-2022)“…We demonstrated that serpinA3c/k relocates from the cytoplasm to the apical tubular membrane (ATM) in chronic kidney disease (CKD), suggesting its secretion in…”
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Epigenetic Effects of an Adenosine Derivative in a Wistar Rat Model of Liver Cirrhosis
Published in Journal of cellular biochemistry (01-01-2018)“…ABSTRACT The pathological characteristic of cirrhosis is scarring which results in a structurally distorted and dysfunctional liver. Previously, we…”
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Physiological Processes Modulated by the Chloride-Sensitive WNK-SPAK/OSR1 Kinase Signaling Pathway and the Cation-Coupled Chloride Cotransporters
Published in Frontiers in physiology (20-10-2020)“…The role of Cl as an intracellular signaling ion has been increasingly recognized in recent years. One of the currently best described roles of Cl in signaling…”
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Vegfa promoter gene hypermethylation at HIF1α binding site is an early contributor to CKD progression after renal ischemia
Published in Scientific reports (22-04-2021)“…Chronic hypoxia is a major contributor to Chronic Kidney Disease (CKD) after Acute Kidney Injury (AKI). However, the temporal relation between the acute insult…”
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C-terminally truncated, kidney-specific variants of the WNK4 kinase lack several sites that regulate its activity
Published in The Journal of biological chemistry (03-08-2018)“…WNK lysine-deficient protein kinase 4 (WNK4) is an important regulator of renal salt handling. Mutations in its gene cause pseudohypoaldosteronism type II,…”
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WNK4 kinase: from structure to physiology
Published in American journal of physiology. Renal physiology (01-03-2021)“…With no lysine kinase-4 (WNK4) belongs to a serine-threonine kinase family characterized by the atypical positioning of its catalytic lysine. Despite the fact…”
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Effect of SARS-CoV-2 S protein on the proteolytic cleavage of the epithelial Na+ channel ENaC
Published in PloS one (25-04-2024)“…Severe cases of COVID-19 are characterized by development of acute respiratory distress syndrome (ARDS). Water accumulation in the lungs is thought to occur as…”
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Molecular mechanisms for the regulation of blood pressure by potassium
Published in Current topics in membranes (2019)“…It has been well documented that the amount of potassium in the diet is associated with blood pressure levels in the population: the higher the potassium…”
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Effect of SARS-CoV-2 S protein on the proteolytic cleavage of the epithelial Na.sup.+ channel ENaC
Published in PloS one (25-04-2024)“…Severe cases of COVID-19 are characterized by development of acute respiratory distress syndrome (ARDS). Water accumulation in the lungs is thought to occur as…”
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10
Arginine vasopressin regulates the renal Na + -Cl - and Na + -K + -Cl - cotransporters through with-no-lysine kinase 4 and inhibitor 1 phosphorylation
Published in American journal of physiology. Renal physiology (01-02-2024)“…Vasopressin regulates water homeostasis via the V2 receptor in the kidney at least in part through protein kinase A (PKA) activation. Vasopressin, through an…”
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