Search Results - "Muriel W. Lambert"
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Development of Effective Skin Cancer Treatment and Prevention in Xeroderma Pigmentosum
Published in Photochemistry and photobiology (01-03-2015)“…Xeroderma pigmentosum (XP) is a rare, recessively transmitted genetic disease characterized by increasingly marked dyspigmentation and xerosis (dryness) of…”
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The functional importance of lamins, actin, myosin, spectrin and the LINC complex in DNA repair
Published in Experimental Biology and Medicine (01-11-2019)“…Three major proteins in the nucleoskeleton, lamins, actin, and spectrin, play essential roles in maintenance of nuclear architecture and the integrity of the…”
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The physiology of melanin deposition in health and disease
Published in Clinics in dermatology (01-09-2019)“…AbstractEumelanin is the major pigment responsible for human skin color. This black/brown pigment is localized in membrane bound organelles, melanosomes, found…”
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The Pathophysiology of Pityriasis Alba: Time-Dependent Histologic Changes
Published in Clinics in dermatology (01-05-2020)“…AbstractAlthough pityriasis alba is a common dermatologic condition, its pathogenesis is poorly understood, and there are many discrepancies in the literature…”
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Spectrin and its interacting partners in nuclear structure and function
Published in Experimental biology and medicine (Maywood, N.J.) (01-03-2018)“…Nonerythroid αII-spectrin is a structural protein whose roles in the nucleus have just begun to be explored. αII-spectrin is an important component of the…”
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Nuclear alpha spectrin: Critical roles in DNA interstrand cross-link repair and genomic stability
Published in Experimental biology and medicine (Maywood, N.J.) (01-09-2016)“…Non-erythroid alpha spectrin (αIISp) is a structural protein which we have shown is present in the nucleus of human cells. It interacts with a number of…”
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Functional Significance of Nuclear α Spectrin
Published in Journal of cellular biochemistry (01-09-2015)“…ABSTRACT Nonerythroid alpha spectrin (αIISp) interacts in the nucleus with an array of different proteins indicating its involvement in a number of diverse…”
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Functional Significance of Nuclear [alpha] Spectrin
Published in Journal of cellular biochemistry (01-09-2015)“…Nonerythroid alpha spectrin ([alpha]IISp) interacts in the nucleus with an array of different proteins indicating its involvement in a number of diverse…”
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Artificial intelligence and the scientific method: How to cope with a complete oxymoron
Published in Clinics in dermatology (01-05-2024)“…Artificial intelligence (AI) can be a powerful tool for data analysis, but it can also mislead investigators, due in part to a fundamental difference between…”
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Nuclear α Spectrin Differentially Affects Monoubiquitinated Versus Non-Ubiquitinated FANCD2 Function After DNA Interstrand Cross-Link Damage
Published in Journal of cellular biochemistry (01-03-2016)“…ABSTRACT Nonerythroid α spectrin (αIISp) and the Fanconi anemia (FA) protein, FANCD2, play critical roles in DNA interstrand cross‐link (ICL) repair during S…”
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Treatment of Postinflammatory Hyperpigmentation: A Dermatologic Challenge
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Annular and acral/facial dyskeratotic paraneoplastic disorders
Published in Clinics in dermatology (01-05-2023)“…Annular and acral/facial dyskeratotic paraneoplastic disorders are inflammatory dermatoses that occur in association with distant cancers but are not…”
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Abstract 2758: FANCF, a Fanconi anemia core complex protein involved in monoubiquitination of FANCD2, also has a role with nuclear alpha spectrin in DNA interstrand crosslink repair
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Nonerythroid nuclear A spectrin (ASpII) is critical for repair of DNA interstrand crosslinks (ICLs) and for genomic stability. We have previously shown that…”
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Occult squamous cell carcinoma within lichenoid dermatitis: three examples of cryptic cancer detection
Published in Archives of dermatological research (01-05-2023)“…Lichenoid dermatitis can be a perplexing entity encompassing an array of cutaneous disorders. Two hundred forty-three (243) cases of otherwise unclassifiable…”
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What we have learned from the COVID-19 pandemic: Time to think outside the box, maybe far outside
Published in Clinics in dermatology (01-01-2021)“…The coronavirus disease 2019 pandemic has had a profound effect on our lives and careers; this presentation explores some of the lessons we have learned from…”
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Novel B-DNA dermatophyte assay for demonstration of canonical DNA in dermatophytes: Histopathologic characterization by artificial intelligence
Published in Clinics in dermatology (01-05-2024)“…We describe a novel assay and artificial intelligence–driven histopathologic approach identifying dermatophytes in human skin tissue sections (ie, B-DNA…”
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Non-erythroid alpha spectrin prevents telomere dysfunction after DNA interstrand cross-link damage
Published in Nucleic acids research (01-05-2013)“…Telomere integrity is critical for telomere function and genomic stability. We previously demonstrated that non-erythroid α-spectrin (αIISp) is present in…”
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The Fanconi Anemia Protein, FANCG, Binds to the ERCC1-XPF Endonuclease via Its Tetratricopeptide Repeats and the Central Domain of ERCC1
Published in Biochemistry (Easton) (06-07-2010)“…There is evidence that Fanconi anemia (FA) proteins play an important role in the repair of DNA interstrand cross-links (ICLs), but the precise mechanism by…”
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Tinea Amianacea: Attack of the Living Dead, Revisited
Published in Skinmed (2024)Get more information
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