Search Results - "Muri, Estela M. F."

Isomannide-Based Peptidomimetics as Inhibitors for Human Tissue Kallikreins 5 and 7 by Oliveira, Jocelia P. C, Freitas, Renato F, Melo, Leandro Silva de, Barros, Thalita G, Santos, Jorge A. N, Juliano, Maria A, Pinheiro, Sérgio, Blaber, Michael, Juliano, Luiz, Muri, Estela M. F, Puzer, Luciano

“…Human kallikrein 5 (KLK5) and 7 (KLK7) are potential targets for the treatment of skin inflammation and cancer. Previously, we identified isomannide…”
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Isomannide derivatives as new class of inhibitors for human kallikrein 7 by Freitas, Renato F., Teixeira, Thiago S.P., Barros, Thalita G., Santos, Jorge A.N., Kondo, Marcia Y., Juliano, Maria A., Juliano, Luiz, Blaber, Michael, Antunes, Octávio A.C., Abrahão, Odonírio, Pinheiro, Sergio, Muri, Estela M.F., Puzer, Luciano

“…Human kallikrein 7 (KLK7) is a potential target for the treatment of skin inflammation and cancer. Despite its potential, few KLK7-specific small-molecule…”
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Pseudo-peptides derived from isomannide: inhibitors of serine proteases by Barros, Thalita G, Pinheiro, Sergio, Williamson, J. S, Tanuri, Amílcar, Gomes, M. Jr, Pereira, Helena S, Brindeiro, R. M, Neto, José B. A, Antunes, O. A. C, Muri, Estela M. F

“…In this paper, we describe the synthesis of a novel class of pseudo-peptides derived from isomannide and several oxazolones as potential inhibitors of serine…”
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Biological evaluation and molecular modeling of peptidomimetic compounds as inhibitors for O-GlcNAc transferase (OGT) by Albuquerque, Suraby O., Barros, Thalita G., Dias, Luiza R.S., Lima, Camilo H. da S., Azevedo, Pedro H.R. de A., Flores-Junior, Luiz A.P., dos Santos, Eldio G., Loponte, Hector F., Pinheiro, Sergio, Dias, Wagner B., Muri, Estela M.F., Todeschini, Adriane R.

“…The vital enzyme O-linked β-N-acetylglucosamine transferase (OGT) catalyzes the O-GlcNAcylation of intracellular proteins coupling the metabolic status to…”
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3-Acyltetramic acids as a novel class of inhibitors for human kallikreins 5 and 7 by de Souza, Acácio S., Pacheco, Barbara D.C., Pinheiro, Sergio, Muri, Estela M.F., Dias, Luiza R.S., Lima, Camilo H.S., Garrett, Rafael, de Moraes, Mariana B.M., de Souza, Bruno E.G., Puzer, Luciano

“…[Display omitted] Human kallikreins 5 and 7 (KLK5 and KLK7) exhibit trypsin- and chymotrypsin-like activities and are involved in pathologies related to skin…”
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Trypanocidal activity of new 1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine derivatives: Synthesis, in vitro and in vivo studies by Ribeiro, Joana L.S., Soares, Júlio C.A.V., Portapilla, Gisele B., Providello, Maiara V., Lima, Camilo H.S., Muri, Estela M.F., de Albuquerque, Sérgio, Dias, Luiza R.S.

“…[Display omitted] •Pyrazolopyridine compounds synthesized and evaluated in vitro/in vivo against T. cruzi.•Benzylidene-carbohydrazide and…”
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Biological activities of [1,2,4]triazolo[1,5-a]pyrimidines and analogs by Pinheiro, Sergio, Pinheiro, Erick M. C., Muri, Estela M. F., Pessôa, Jaqueline C., Cadorini, Mayara A., Greco, Sandro J.

“…The [1,2,4]triazolo[1,5- a ]pyrimidines (TPs) comprise an important class of non-naturally occurring small molecules that aroused the interest of researches…”
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2H-1,2,3-Triazole-chalcones as novel cytotoxic agents against prostate cancer by Pinheiro, Sergio, Pessôa, Jaqueline C., Pinheiro, Erick M.C., Muri, Estela M.F., Filho, Eclair Venturini, Loureiro, Laiza B., Freitas, Maria Clara R., Silva Junior, Carlos M.D., Fiorot, Rodolfo G., Carneiro, José Walkimar M., Rotamiro, Karina M., Guimarães, Anderson R.A., Rocha-Brito, Karin J.P., Greco, Sandro J.

“…[Display omitted] Prostate cancer is an important cause of death in the male population and for which there is no satisfactory chemotherapy. Herein a new…”
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Synthesis and mechanistic evaluation of novel N’-benzylidene-carbohydrazide-1H-pyrazolo[3,4-b]pyridine derivatives as non-anionic antiplatelet agents by Lourenço, André L., Salvador, Raquel R.S., Silva, Leonardo A., Saito, Max S., Mello, Juliana F.R., Cabral, Lúcio M., Rodrigues, Carlos R., Vera, Maria A.F., Muri, Estela M.F., de Souza, Alessandra M.T., Craik, Charles S., Dias, Luiza R.S., Castro, Helena C., Sathler, Plínio C.

“…Cardiovascular diseases (CVDs) account for over 17 million deaths globally each year, with atherosclerosis as the underlying cause of most CVDs. Herein we…”
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Synthesis, biological evaluation and molecular modeling of pseudo-peptides based statine as inhibitors for human tissue kallikrein 5 by Hoelz, Lucas V.B., Zorzanelli, Bruna C., Azevedo, Pedro Henrique R.de A., Passos, Silvia G., de Souza, Lucas R., Zani, Marcelo, Pinheiro, Sergio, Puzer, Luciano, Dias, Luiza R.S., Muri, Estela M.F.

“…Human kallikrein 5 (KLK5) is a potential target for the treatment of skin inflammation and cancer. A new series of statine based peptidomimetic compounds were…”
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Isosorbide-based peptidomimetics as inhibitors of hepatitis C virus serine protease by Portela, Aline C., Barros, Thalita G., Lima, Camilo H. da S., Dias, Luiza R.S., Azevedo, Pedro H.R. de A., Dantas, Anna Sophia C.L., Mohana-Borges, Ronaldo, Ventura, Gustavo T., Pinheiro, Sergio, Muri, Estela M.F.

“…[Display omitted] Hepatitis C infection is a cause of chronic liver diseases such as cirrhosis and carcinoma. The current therapy for hepatitis C has limited…”
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Discovery of a new isomannide-based peptidomimetic synthetized by Ugi multicomponent reaction as human tissue kallikrein 1 inhibitor by Barros, Thalita G., Santos, Jorge A.N., de Souza, Bruno E.G., Sodero, Ana Carolina R., de Souza, Alessandra M.T., da Silva, Dayane P., Rodrigues, Carlos Rangel, Pinheiro, Sergio, Dias, Luiza R.S., Abrahim-Vieira, Bárbara, Puzer, Luciano, Muri, Estela M.F.

“…[Display omitted] Human kallikrein 1 (KLK1) is the most extensively studied member of this family and plays a major role in inflammation processes. From Ugi…”
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New carbohydrazide derivatives of 1H-pyrazolo[3,4-b]pyridine and trypanocidal activity by Salvador, Raquel R S, Bello, Murilo L, Barreto, Igor R L, Vera, Maria A F, Muri, Estela M F, Albuquerque, Sérgio DE, Dias, Luiza R S

“…This paper reports the in vitro trypanocidal activity evaluation of new carbohydrazide derivatives from 3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine,…”
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Novel isomannide-based peptide mimetics containing a tartaric acid backbone as serine protease inhibitors by Abrahim-Vieira, Bárbara, da Costa, Emmerson C. B., de A. Azevedo, Pedro H. R., Portela, Aline C., Dias, Luiza R. S., Pinheiro, Sergio, Tanuri, Amilcar, Capaccia, Anne M., Ventura, Gustavo T., Mohana-Borges, Ronaldo, Rodrigues, Carlos R., de Souza, Alessandra M. T., Muri, Estela M. F.

“…Hepatitis C viral infection is a cause of chronic liver disease, and current therapies are only effective in 50 % of patients. Serine proteases, which are…”
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A general approach for the synthesis of 5-substituted-4-amino-pyrrolidin-2-ones and 5-substituted-4-amino-3-pyrrolin-2-ones by Pinheiro, Sergio, da Silva Júnior, Ronaldo C., de Souza, Acácio Silva, de M. Carneiro, José Walkimar, Muri, Estela M.F., Antunes, O.A.C.

“…Simple protocols for the syntheses of both 5-substituted-4-amino-pyrrolidin-2-ones and 3-pyrrolin-2-ones from tetramic acids are presented. Short…”
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Polímeros de impressão molecular obtidos através de polimerização por precipitação e sua aplicação na técnica de extração em fase sólida by Bruna Rachel de B. Peçanha, Luiza R. S. Dias, Eliani Spinelli, Estela M. F. Muri

“…Polímeros de impressão molecular (Molecularly Imprinted Polymers, MIPs) foram sintetizados e aplicados como adsorventes na técnica de extração em fase sólida…”
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Catalytic oxidation of isosafrol by vanadium complexes by Alvarez, Heiddy Marquez, de Andrade, Joyce L., Pereira, Nei, Muri, Estela M.F., Horn, Adolfo, Barbosa, Dayse Pereira, Antunes, O.A.C.

“…1,2-methylenedioxy-4(1-propenyl)benzene, isosafrol ( 1a), is an important intermediate for the synthesis of drugs like L-DOPA. In this work, different vanadium…”
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Polímeros de impressão molecular obtidos através de polimerização por precipitação e sua aplicação na técnica de extração em fase sólida Molecularly imprinted polymers prepared by precipitation polymerization and their application to solid phase extraction by Bruna Rachel de B. Peçanha, Luiza R. S. Dias, Eliani Spinelli, Estela M. F. Muri

“…Polímeros de impressão molecular (Molecularly Imprinted Polymers, MIPs) foram sintetizados e aplicados como adsorventes na técnica de extração em fase sólida…”
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Synthesis of New Benzylic Ethers of Oximes Derived from 1-Phenyl-pyrazole Compounds by Muri, Estela M. F., Barreiro, Eliezer J., Fraga, Carlos A. M.

“…In the scope of a research program aiming at the synthesis and pharmacological evaluation of new antithrombotic agents via rational molecular design, we…”
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