Search Results - "Murgida, Daniel"
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Multifunctional Cytochrome c: Learning New Tricks from an Old Dog
Published in Chemical reviews (08-11-2017)“…Cytochrome c (cyt c) is a small soluble heme protein characterized by a relatively flexible structure, particularly in the ferric form, such that it is able to…”
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Alternative Conformations of Cytochrome c: Structure, Function, and Detection
Published in Biochemistry (Easton) (26-01-2016)“…Cytochrome c (cyt c) is a cationic hemoprotein of ∼100 amino acid residues that exhibits exceptional functional versatility. While its primary function is…”
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In Situ Spectroelectrochemical Investigations of Electrode-Confined Electron-Transferring Proteins and Redox Enzymes
Published in ACS omega (09-02-2021)“…This perspective analyzes recent advances in the spectroelectrochemical investigation of redox proteins and enzymes immobilized on biocompatible or biomimetic…”
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Electrochemical Actuation of a DyP Peroxidase: A Facile Method for Drastic Improvement of the Catalytic Performance
Published in ACS catalysis (02-06-2023)“…Dye decolorizing peroxidases (DyP) have attracted interest for applications such as dye-containing wastewater remediation and biomass processing. So far,…”
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Disentangling interfacial redox processes of proteins by SERR spectroscopy
Published in Chemical Society reviews (01-01-2008)“…Surface-enhanced resonance-Raman spectroelectrochemistry represents a powerful approach for studying the structure and reaction dynamics of redox proteins…”
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Determination of the Local Electric Field at Au/SAM Interfaces Using the Vibrational Stark Effect
Published in Journal of physical chemistry. C (12-10-2017)“…A comprehensive understanding of physical and chemical processes at biological membranes requires the knowledge of the interfacial electric field which is a…”
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7
Autocatalytic Mechanism in the Anaerobic Reduction of Metmyoglobin by Sulfide Species
Published in Inorganic chemistry (24-07-2023)“…The mechanism of the metal centered reduction of metmyoglobin (MbFeIII) by sulfide species (H2S/HS–) under an argon atmosphere has been studied by a…”
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Direct Electrochemical Generation of Catalytically Competent Oxyferryl Species of Classes I and P Dye Decolorizing Peroxidases
Published in International journal of molecular sciences (20-11-2021)“…This work introduces a novel way to obtain catalytically competent oxyferryl species for two different dye-decolorizing peroxidases (DyPs) in the absence of H…”
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Electron-Transfer Processes of Cytochrome c at Interfaces. New Insights by Surface-Enhanced Resonance Raman Spectroscopy
Published in Accounts of chemical research (01-11-2004)“…The heme protein cytochrome c acts as an electron carrier at the mitochondrial-membrane interface and thus exerts its function under the influence of strong…”
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10
Reduction of metmyoglobin by inorganic disulfide species
Published in Journal of inorganic biochemistry (01-08-2023)“…The mechanism of the metal centered reduction of metmyoglobin (MbFeIII) by inorganic disulfide species has been studied by combined spectroscopic and kinetic…”
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Correlated electric field modulation of electron transfer parameters and the access to alternative conformations of multifunctional cytochrome c
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01-02-2022)“…•Electric fields modulate cytochrome c electron transfer and conformational dynamics.•Kinetic electron transfer and conformational parameters of Cyt c are…”
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Dynamical effects in metalloprotein heterogeneous electron transfer
Published in Electrochimica acta (10-05-2020)“…In this work we assess the influence of physiological viscosities on metalloprotein electron transfer reactions. To that end we investigated the direct…”
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Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite
Published in Free radical biology & medicine (01-10-2018)“…Cationic manganese(III) ortho N-substituted pyridylporphyrins (MnP) act as efficient antioxidants catalyzing superoxide dismutation and accelerating…”
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Active Site Structure and Peroxidase Activity of Oxidatively Modified Cytochrome c Species in Complexes with Cardiolipin
Published in Biochemistry (Easton) (29-12-2015)“…We report a resonance Raman and UV–vis characterization of the active site structure of oxidatively modified forms of cytochrome c (Cyt-c) free in solution and…”
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Electron transfer and conformational transitions of cytochrome c are modulated by the same dynamical features
Published in Archives of biochemistry and biophysics (15-02-2020)“…Cytochrome c is a prototypical multifunctional protein that is implicated in a variety of processes that are essential both for sustaining and for terminating…”
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The role of protein dynamics and thermal fluctuations in regulating cytochrome c/cytochrome c oxidase electron transfer
Published in Biochimica et biophysica acta (01-07-2014)“…In this overview we present recent combined electrochemical, spectroelectrochemical, spectroscopic and computational studies from our group on the electron…”
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Mutational Analysis of Deinococcus radiodurans Bacteriophytochrome Reveals Key Amino Acids Necessary for the Photochromicity and Proton Exchange Cycle of Phytochromes
Published in The Journal of biological chemistry (02-05-2008)“…The ability of phytochromes (Phy) to act as photointerconvertible light switches in plants and microorganisms depends on key interactions between the bilin…”
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The Chromophore Structural Changes during the Photocycle of Phytochrome: A Combined Resonance Raman and Quantum Chemical Approach
Published in Accounts of chemical research (01-04-2007)“…Phytochromes are sensory photoreceptors that, upon light irradiation, can be transformed between an inactive and an active state. The conversion is initiated…”
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Electrochemical characterization of an engineered red copper protein featuring an unprecedented entropic control of the reduction potential
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01-08-2022)“…•Ligand loop replacement of a CuA site leads to a T2-like mononuclear copper protein.•The T2 chimera is the first Cu site with entropically controlled redox…”
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Self-Assembled Monolayers of NH2-Terminated Thiolates: Order, pKa, and Specific Adsorption
Published in Langmuir (30-04-2013)“…Self-assembled monolayers (SAMs) of amino-terminated alkanethiols on Au were characterized by a combination of electrochemical (LSV, CV, and EIS) and…”
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