Search Results - "Murdoch, Geoffrey"

Amphetamine activates Rho GTPase signaling to mediate dopamine transporter internalization and acute behavioral effects of amphetamine by Wheeler, David S., Underhill, Suzanne M., Stolz, Donna B., Murdoch, Geoffrey H., Thiels, Edda, Romero, Guillermo, Amara, Susan G.

“…Acute amphetamine (AMPH) exposure elevates extracellular dopamine through a variety of mechanisms that include inhibition of dopamine reuptake, depletion of…”
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Diagnostic Use of IDH1/2 Mutation Analysis in Routine Clinical Testing of Formalin-Fixed, Paraffin-Embedded Glioma Tissues by Horbinski, Craig, Kofler, Julia, Kelly, Lindsey M, Murdoch, Geoffrey H, Nikiforova, Marina N

“…Mutations in isocitrate dehydrogenase enzyme isoforms 1 (IDH1) and 2 (IDH2) have been identified in many adult astrocytomas and oligodendrogliomas. These…”
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Human Parechovirus 3 Meningitis and Fatal Leukoencephalopathy by Bissel, Stephanie J., Auer, Roland N., Chiang, Cheng-Hsuan, Kofler, Julia, Murdoch, Geoffrey H., Nix, W. Allan, Painter, Michael, Richer, Maxime, Sartelet, Hervé, Wang, Guoji, Wiley, Clayton A.

“…Human parechovirus 3 (HPeV3) is a picornavirus associated with neurologic disease in neonates. Human parechovirus 3 infection of preterm and term infants is…”
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Role of CHI3L1 in neuroinflammation by Wiley, Clayton A, Bissel, Stephanie J, Murdoch, Geoffrey H

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The dominant TP53 hotspot mutation in IDH-mutant astrocytoma, R273C, has distinctive pathologic features and sex-specific prognostic implications by Marker, Daniel F, Agnihotri, Sameer, Amankulor, Nduka, Murdoch, Geoffrey H, Pearce, Thomas M

“…Abstract Background Infiltrative astrocytic tumors with and without isocitrate dehydrogenase (IDH) mutation frequently contain mutations in the TP53 tumor…”
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Progressive Right-Sided Hemiparesis in a Man With Sarcoidosis by Galdys, Alison L, Kale, Hrishikesh A, Lacomis, David, Vergidis, Pascalis, Murdoch, Geoffrey H

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Selective vulnerability of preterm white matter to oxidative damage defined by F2-isoprostanes by Back, Stephen A., Luo, Ning Ling, Mallinson, Rebecca A., O'Malley, Jean P., Wallen, Linda D., Frei, Balz, Morrow, Jason D., Petito, Carol K., Roberts Jr, Charles T., Murdoch, Geoffrey H., Montine, Thomas J.

“…Periventricular white matter injury (PWMI) is the leading cause of cerebral palsy and chronic neurological disability in survivors of prematurity. Despite the…”
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Differential loss of synaptic proteins in Alzheimer's disease: implications for synaptic dysfunction by Reddy, P Hemachandra, Mani, Geethalakshmi, Park, Byung S, Jacques, Joline, Murdoch, Geoffrey, Whetsell, Jr, William, Kaye, Jeffrey, Manczak, Maria

“…The objective of our research was to determine synaptic protein levels in brain specimens from AD subjects and age-matched control subjects. Further, to…”
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Isocitrate Dehydrogenase 1 Analysis Differentiates Gangliogliomas from Infiltrative Gliomas by Horbinski, Craig, Kofler, Julia, Yeaney, Gabrielle, Camelo-Piragua, Sandra, Venneti, Sriram, Louis, David N., Perry, Arie, Murdoch, Geoffrey, Nikiforova, Marina

“…Recent work has identified novel point mutations in isocitrate dehydrogenase 1 (IDH1) in the majority of the World Health Organization grades II and III…”
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Progressive Right-Sided Hemiparesis in a Man With Sarcoidosis by Galdys, Alison L., Kale, Hrishikesh A., Lacomis, David, Vergidis, Pascalis, Murdoch, Geoffrey H.

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Preventive immunization of aged and juvenile non-human primates to β-amyloid by Kofler, Julia, Lopresti, Brian, Janssen, Chris, Trichel, Anita M, Masliah, Eliezer, Finn, Olivera J, Salter, Russell D, Murdoch, Geoffrey H, Mathis, Chester A, Wiley, Clayton A

“…Immunization against beta-amyloid (Aβ) is a promising approach for the treatment of Alzheimer's disease, but the optimal timing for the vaccination remains to…”
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Identification and characterization of new long chain Acyl-CoA dehydrogenases by He, Miao, Pei, Zhengtong, Mohsen, Al-Walid, Watkins, Paul, Murdoch, Geoffrey, Van Veldhoven, Paul P., Ensenauer, Regina, Vockley, Jerry

“…Long-chain fatty acids are an important source of energy in muscle and heart where the acyl-CoA dehydrogenases (ACADs) participate in consecutive cycles of…”
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Intracranial angiomatoid fibrous histiocytoma presenting as recurrent multifocal intraparenchymal hemorrhage: Case report by OCHALSKI, Pawel G, EDINGER, James T, HOROWITZ, Michael B, STETLER, William R, MURDOCH, Geoffrey H, KASSAM, Amin B, ENGH, Johnathan A

“…Angiomatoid fibrous histiocytoma (AFH) is a rare soft-tissue neoplasm that most commonly appears in the limbs, typically affecting children and young adults…”
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Neuropathology of 22q11 Deletion Syndrome in an Infant by Wu, Peter, Teot, Lisa, Murdoch, Geoffrey, Monaghan-Nichols, A. Paula, McFadden, Kathryn

“…The 22q11 deletion syndrome (22q11DS) is the most common microdeletion syndrome in humans and one of the chromosomal conditions most associated with psychosis…”
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Masson tumor (intravascular papillary endothelial hyperplasia) arising in a superficial temporal artery aneurysm by Chapman, Scott C., MD, Zak, Peter W., MD, Scaife, Mark, MD, Murdoch, Geoffrey, MD, Eslami, Mohammad H., MD

“…AbstractMasson tumor (intravascular papillary endothelial hyperplasia) is a rare proliferation of endothelial cells within the wall of a vessel, often thought…”
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Preterm fetal hypoxia-ischemia causes hypertonia and motor deficits in the neonatal rabbit: a model for human cerebral palsy? by Derrick, Matthew, Luo, Ning Ling, Bregman, Joanne C, Jilling, Tamas, Ji, Xinhai, Fisher, Kara, Gladson, Candece L, Beardsley, Douglas J, Murdoch, Geoffrey, Back, Stephen A, Tan, Sidhartha

“…Prenatal hypoxia-ischemia to the developing brain has been strongly implicated in the subsequent development of the hypertonic motor deficits of cerebral palsy…”
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Akt activation is a common event in pediatric malignant gliomas and a potential adverse prognostic marker: a report from the Children’s Oncology Group by Pollack, Ian F., Hamilton, Ronald L., Burger, Peter C., Brat, Daniel J., Rosenblum, Marc K., Murdoch, Geoffrey H., Nikiforova, Marina N., Holmes, Emiko J., Zhou, Tianni, Cohen, Kenneth J., Jakacki, Regina I.

“…Aberrant activation of Akt is a common finding in adult malignant gliomas, resulting in most cases from mutations or deletions involving PTEN , which allows…”
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Subacute histopathological features in a case of varicella zoster virus myelitis and post-herpetic neuralgia by Moshayedi, Pouria, Thomas, Diana, Rinaldo, Charles R., Moossy, John J., Maroon, Joseph C., Murdoch, Geoffrey H., Hamilton, Ronald L., Homayoun, Houman

“…Introduction Post-herpetic neuralgia is a crippling complication of varicella zoster virus (VZV) reactivation, also known as zoster disease. In rare cases, VZV…”
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Posterior reversible encephalopathy syndrome (PRES) with immune system activation, VEGF up-regulation, and cerebral amyloid angiopathy by Kofler, Julia, Bartynski, Walter S, Reynolds, Thomas Q, Lieberman, Frank S, Murdoch, Geoffrey H, Hamilton, Ronald L

“…The case of a 75-year-old man with a history of lymphoma, recent upper respiratory tract infection, and a protracted course of encephalopathy is presented…”
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Neuropathology in Succinic Semialdehyde Dehydrogenase Deficiency by Knerr, Ina, MD, Gibson, K. Michael, PhD, Murdoch, Geoffrey, MD, PhD, Salomons, Gajja S., PhD, Jakobs, Cornelis, PhD, Combs, Susan, BA, Pearl, Phillip L., MD

“…Reported here is the novel finding of neuropathology in a patient with succinic semialdehyde dehydrogenase deficiency, an inherited disorder of γ-aminobutyric…”
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