Search Results - "Murdoch, David M."
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Incidence and risk factors for the immune reconstitution inflammatory syndrome in HIV patients in South Africa: a prospective study
Published in AIDS (London) (12-03-2008)“…To determine the incidence, clinical manifestations, risk factors and outcome of immune reconstitution inflammatory syndrome (IRIS) in South Africa…”
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2
Causes of death on antiretroviral therapy: a post-mortem study from South Africa
Published in PloS one (16-10-2012)“…Mortality in the first months of antiretroviral therapy (ART) is a significant clinical problem in sub-Saharan Africa. To date, no post-mortem study has…”
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3
Transcriptional Profiling of CD8+ CMV-Specific T Cell Functional Subsets Obtained Using a Modified Method for Isolating High-Quality RNA From Fixed and Permeabilized Cells
Published in Frontiers in immunology (02-09-2020)“…Previous studies suggest that the presence of antigen-specific polyfunctional T cells is correlated with improved pathogen clearance, disease control, and…”
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4
Asthma, Airflow Obstruction, and Eosinophilic Airway Inflammation Prevalence in Western Kenya: A Population-Based Cross-Sectional Study
Published in International journal of public health (17-08-2023)“…Objectives: Determine the prevalence of airway disease (e.g., asthma, airflow obstruction, and eosinophilic airway inflammation) in Kenya, as well as related…”
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5
Automated microarray platform for single-cell sorting and collection of lymphocytes following HIV reactivation
Published in Bioengineering & translational medicine (01-09-2023)“…A promising strategy to cure HIV-infected individuals is to use latency reversing agents (LRAs) to reactivate latent viruses, followed by host clearance of…”
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Immune reconstitution inflammatory syndrome (IRIS): review of common infectious manifestations and treatment options
Published in AIDS research and therapy (08-05-2007)“…The immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients initiating antiretroviral therapy (ART) results from restored immunity to…”
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Probing gut‐brain links in Alzheimer's disease with rifaximin
Published in Alzheimer's & dementia : translational research & clinical interventions (2022)“…Gut‐microbiome‐inflammation interactions have been linked to neurodegeneration in Alzheimer's disease (AD) and other disorders. We hypothesized that treatment…”
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Prevalence and phenotypic trajectories of hypoxaemia among hospitalised adults in Kenya: a single-centre, prospective cohort study
Published in BMJ open (18-09-2023)“…Objective Global medical oxygen security is limited by knowledge gaps in hypoxaemia burden and oxygen access in low-income and middle-income countries. We…”
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Scalable Additive Construction of Arrayed Microstructures with Encoded Properties for Bioimaging
Published in Micromachines (Basel) (25-08-2022)“…Microarrays are essential components of analytical instruments. The elements of microarrays may be imbued with additional functionalities and encodings using…”
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Immune Restoration Diseases Reflect Diverse Immunopathological Mechanisms
Published in Clinical Microbiology Reviews (01-10-2009)“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Mycobacterium avium-intracellulare cellulitis occurring with septic arthritis after joint injection: a case report
Published in BMC infectious diseases (26-02-2007)“…Cellulitis caused by Mycobacterium avium-intracellulare has rarely been described. Mycobacterium avium-intracellulare is a rare cause of septic arthritis after…”
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12
Multi-analyte profiling of ten cytokines in South African HIV-infected patients with Immune Reconstitution Inflammatory Syndrome (IRIS)
Published in AIDS research and therapy (07-10-2010)“…Immune reconstitution inflammatory syndrome (IRIS) is an important complication of HAART in sub-Saharan Africa, where opportunistic infections (OIs) including…”
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13
Plasma Neurofilament Light Chain as a Translational Biomarker of Aging and Neurodegeneration in Dogs
Published in Molecular neurobiology (01-07-2020)“…Age is a primary risk factor for multiple comorbidities including neurodegenerative diseases. Pet dogs and humans represent two populations that have…”
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Plasma Amyloid Beta Concentrations in Aged and Cognitively Impaired Pet Dogs
Published in Molecular neurobiology (01-02-2021)“…Longevity-associated neurological disorders have been observed across human and canine aging populations. Alzheimer’s disease (AD) and canine cognitive…”
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15
Magnetophoretic transistors in a tri-axial magnetic field
Published in Lab on a chip (18-10-2016)“…The ability to direct and sort individual biological and non-biological particles into spatially addressable locations is fundamentally important to the…”
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16
LXR signaling pathways link cholesterol metabolism with risk for prediabetes and diabetes
Published in The Journal of clinical investigation (15-08-2024)Get full text
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Use of Cognitive Testing, Questionnaires, and Plasma Biomarkers to Quantify Cognitive Impairment in an Aging Pet Dog Population
Published in Journal of Alzheimer's disease (2022)“…Aging dogs may suffer from canine cognitive dysfunction syndrome (CCDS), a condition in which cognitive decline is associated with amyloid pathology and…”
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Heparin-based blood purification attenuates organ injury in baboons with Streptococcus pneumoniae pneumonia
Published in American journal of physiology. Lung cellular and molecular physiology (01-08-2021)“…Bacterial pneumonia is a major cause of morbidity and mortality worldwide despite the use of antibiotics, and novel therapies are urgently needed. Building on…”
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Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy
Published in eLife (09-09-2024)“…Understanding the interplay between the HIV reservoir and the host immune system may yield insights into HIV persistence during antiretroviral therapy (ART)…”
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LXR signaling pathways link cholesterol metabolism with risk for prediabetes and diabetes
Published in The Journal of clinical investigation (15-05-2024)“…BACKGROUNDPreclinical studies suggest that cholesterol accumulation leads to insulin resistance. We previously reported that alterations in a monocyte…”
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