Search Results - "Muratoglu, Orhun K"

Investigation of surgically retrieved, vitamin E-stabilized, crosslinked UHMWPE implants after short-term in vivo service by Rowell, Shannon L., Muratoglu, Orhun K.

“…Antioxidant stabilized highly crosslinked ultra-high molecular weight polyethylene (UHMWPE) components have been in clinical use since 2008. In vitro testing…”
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Synergistic use of anti-inflammatory ketorolac and gentamicin to target staphylococcal biofilms by Sekar, Amita, Gil, Dmitry, Tierney, Peyton, McCanne, Madeline, Daesety, Vikram, Trendafilova, Darina, Muratoglu, Orhun K, Oral, Ebru

“…While antibiotics remain our primary tools against microbial infection, increasing antibiotic resistance (inherent and acquired) is a major detriment to their…”
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A new mechanism of oxidation in ultrahigh molecular weight polyethylene caused by squalene absorption by Oral, Ebru, Ghali, Bassem W., Neils, Andrew, Muratoglu, Orhun K.

“…Although synovial fluid lipids were found to absorb in ultrahigh molecular weight polyethylene (UHMWPE) total joint implants in vivo, their effect on the…”
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In‐vitro oxidation model for UHMWPE incorporating synovial fluid lipids by Oral, Ebru, Fung, Mitchell, Rowell, Shannon L., Muratoglu, Orhun K.

“…ABSTRACT Post‐irradiation melting of ultra‐high molecular weight polyethylene (UHMWPE) reduced the oxidation potential of UHMWPE in vivo. After mid‐term (5–10…”
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Ex Vivo Stability Loss of Irradiated and Melted Ultra-High Molecular Weight Polyethylene by Muratoglu, Orhun K, Wannomae, Keith K, Rowell, Shannon L, Micheli, Brad R, Malchau, Henrik

“…BACKGROUND:Radiation crosslinking reduces wear of ultra-high molecular weight polyethylene (UHMWPE), and subsequent annealing or melting increases oxidative…”
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ACL substitution may improve kinematics of PCL-retaining total knee arthroplasty by Zumbrunn, Thomas, Duffy, Michael P., Rubash, Harry E., Malchau, Henrik, Muratoglu, Orhun K., Varadarajan, Kartik Mangudi

“…Purpose One of the key factors responsible for altered kinematics and joint stability following contemporary total knee arthroplasty (TKA) is resection of the…”
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The effects of high dose irradiation on the cross-linking of vitamin E-blended ultrahigh molecular weight polyethylene by Oral, Ebru, Godleski Beckos, Christine, Malhi, Arnaz S, Muratoglu, Orhun K

“…Abstract Vitamin E-stabilized, highly cross-linked ultrahigh molecular weight polyethylene (UHMWPE) is a promising oxidation and wear resistant UHMWPE with…”
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Vitamin E-Diffused Highly Cross-Linked UHMWPE Particles Induce Less Osteolysis Compared to Highly Cross-Linked Virgin UHMWPE Particles In Vivo by Bichara, David A., MD, Malchau, Erik, MD, Sillesen, Nanna H., MD, Cakmak, Selami, MD, Nielsen, G. Petur, MD, Muratoglu, Orhun K., PhD

“…Abstract Recent in vitro findings suggest that UHMWPE wear particles containing vitamin E (VE) may have reduced biologic activity and decreased osteolytic…”
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Regaining Native Knee Kinematics Following Joint Arthroplasty: A Novel Biomimetic Design with ACL and PCL Preservation by Zumbrunn, Thomas, MS, Varadarajan, Kartik Mangudi, PhD, Rubash, Harry E., MD, Malchau, Henrik, MD, PhD, Li, Guoan, PhD, Muratoglu, Orhun K., PhD

“…Abstract Lack of ACL and non-anatomic articular surfaces in contemporary total knee implants result in kinematic abnormalities. We hypothesized that such…”
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Cruciate Retaining Implant With Biomimetic Articular Surface to Reproduce Activity Dependent Kinematics of the Normal Knee by Varadarajan, Kartik Mangudi M., PhD, Zumbrunn, Thomas, MS, Rubash, Harry E., MD, Malchau, Henrik, MD, PhD, Li, Guoan, PhD, Muratoglu, Orhun K., PhD

“…Abstract Alterations in normal knee kinematics following total knee arthroplasty (TKA) arise in part from the non-anatomic articular geometry of contemporary…”
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Increasing irradiation temperature maximizes vitamin E grafting and wear resistance of ultrahigh molecular weight polyethylene by Oral, Ebru, Neils, Andrew L., Rowell, Shannon L, Lozynsky, Andrew J., Muratoglu, Orhun K.

“…Vitamin E stabilization of radiation crosslinked ultrahigh molecular weight polyethylene (UHMWPE) for total joint implants can be done by blending of UHMWPE…”
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Diffusion of vitamin E in ultra-high molecular weight polyethylene by Oral, Ebru, Wannomae, Keith K, Rowell, Shannon L, Muratoglu, Orhun K

“…Abstract Vitamin E-doped, radiation crosslinked ultra-high molecular weight polyethylene (UHMWPE) is developed as an alternate oxidation and wear resistant…”
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Knee Simulator Wear of Vitamin E Stabilized Irradiated Ultrahigh Molecular Weight Polyethylene by Micheli, Brad R., BS, Wannomae, Keith K., BS, Lozynsky, Andrew J., BS, Christensen, Steven D., BA, Muratoglu, Orhun K., PhD

“…Abstract Wear and damage of ultrahigh molecular weight polyethylene (UHMWPE) tibial inserts used in total knee arthroplasty are accelerated by oxidation…”
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In Vivo Oxidative Stability Changes of Highly Cross-Linked Polyethylene Bearings: An Ex Vivo Investigation by Rowell, Shannon L., BS, Reyes, Christopher R., BS, Malchau, Henrik, MD, PhD, Muratoglu, Orhun K., PhD

“…Abstract The development of highly cross-linked UHMWPEs focused on stabilizing radiation-induced free radicals as the sole precursor to oxidative degradation…”
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Improved resistance to wear and fatigue fracture in high pressure crystallized vitamin E-containing ultra-high molecular weight polyethylene by Oral, Ebru, Godleski Beckos, Christine A, Lozynsky, Andrew J, Malhi, Arnaz S, Muratoglu, Orhun K

“…Abstract Higher crystallinity and extended chain morphology are induced in ultra-high molecular weight polyethylene (UHMWPE) in the hexagonal phase at…”
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Quantifying the lubricity of mechanically tough polyvinyl alcohol hydrogels for cartilage repair by Ling, Doris, Bodugoz-Senturk, Hatice, Nanda, Salil, Braithwaite, Gavin, Muratoglu, Orhun K

“…Polyvinyl alcohol hydrogels are biocompatible and can be used as synthetic articular cartilage. Their mechanical characteristics can be tailored by various…”
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Worse health-related quality of life and hip function in female patients with elevated chromium levels: A prospective study of 659 patients with a recalled THR metal-on-metal implant by Hussey, Daniel K, Madanat, Rami, Donahue, Gabrielle S, Rolfson, Ola, Muratoglu, Orhun K, Malchau, Henrik

“…Background and purpose - Blood metal ion levels can be an indicator for detecting implant failure in metal-on-metal (MoM) hip arthroplasties. Little is known…”
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Fracture of a Cross-Linked Polyethylene Liner Due to Impingement by Duffy, Gavan P., MD, Wannomae, Keith K., BS, Rowell, Shannon L., BS, Muratoglu, Orhun K., PhD

“…Abstract We report a case of fracture at 2 years after implantation of a 50-kGy moderately cross-linked ultrahigh molecular weight polyethylene liner with an…”
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Surface cross-linked UHMWPE can enable the use of larger femoral heads in total joints by Oral, Ebru, Neils, Andrew L., Lyons, Chelsea, Fung, Mitchell, Doshi, Brinda, Muratoglu, Orhun K.

“…Limiting cross‐linking to the articular surfaces of ultrahigh molecular weight polyethylene (UHMWPE) to increase wear resistance while preventing detrimental…”
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Porous Poly(vinyl alcohol)-Alginate Gel Hybrid Construct for Neocartilage Formation Using Human Nasoseptal Cells by Bichara, David A., M.D, Zhao, Xing, M.D, Hwang, Nathaniel S., Ph.D, Bodugoz-Senturk, Hatice, Ph.D, Yaremchuk, Michael J., M.D, Randolph, Mark A., M.A.S, Muratoglu, Orhun K., Ph.D

“…Background Limited options exist for the restoration of craniofacial cartilage. Autologous tissue or porous polyethylene is currently used for nasal and…”
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