Search Results - "Murata, Kozue"

Establishment of a heart-on-a-chip microdevice based on human iPS cells for the evaluation of human heart tissue function by Abulaiti, Mosha, Yalikun, Yaxiaer, Murata, Kozue, Sato, Asako, Sami, Mustafa M., Sasaki, Yuko, Fujiwara, Yasue, Minatoya, Kenji, Shiba, Yuji, Tanaka, Yo, Masumoto, Hidetoshi

“…Human iPS cell (iPSC)-derived cardiomyocytes (CMs) hold promise for drug discovery for heart diseases and cardiac toxicity tests. To utilize human iPSC-derived…”
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miR-124-3p downregulates EGR1 to suppress ischemia-hypoxia reperfusion injury in human iPS cell-derived cardiomyocytes by Yang, Qiaoke, Murata, Kozue, Ikeda, Tadashi, Minatoya, Kenji, Masumoto, Hidetoshi

“…Ischemic heart diseases are a major global cause of death, and despite timely revascularization, heart failure due to ischemia-hypoxia reperfusion (IH/R)…”
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In vivo recellularization of xenogeneic vascular grafts decellularized with high hydrostatic pressure method in a porcine carotid arterial interpose model by Kurokawa, Shunji, Hashimoto, Yoshihide, Funamoto, Seiichi, Murata, Kozue, Yamashita, Akitatsu, Yamazaki, Kazuhiro, Ikeda, Tadashi, Minatoya, Kenji, Kishida, Akio, Masumoto, Hidetoshi

“…Autologous vascular grafts are widely used in revascularization surgeries for small caliber targets. However, the availability of autologous conduits might be…”
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Pioglitazone-incorporated microspheres targeting macrophage polarization alleviates cardiac dysfunction after myocardial infarction by Konegawa, Yasushi, Kuwahara, Toshie, Jo, Jun-Ichiro, Murata, Kozue, Takeda, Takahide, Ikeda, Tadashi, Minatoya, Kenji, Masumoto, Hidetoshi, Tabata, Yasuhiko

“…Abstract OBJECTIVES Excessive and chronic inflammation after a myocardial infarction (MI) is associated with left ventricular remodelling and impaired cardiac…”
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Immunoregulatory effect of bifidobacteria strains in porcine intestinal epithelial cells through modulation of ubiquitin-editing enzyme A20 expression by Tomosada, Yohsuke, Villena, Julio, Murata, Kozue, Chiba, Eriko, Shimazu, Tomoyuki, Aso, Hisashi, Iwabuchi, Noriyuki, Xiao, Jin-zhong, Saito, Tadao, Kitazawa, Haruki

“…We previously showed that evaluation of anti-inflammatory activities of lactic acid bacteria in porcine intestinal epithelial (PIE) cells is useful for…”
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Strategies for immune regulation in iPS cell-based cardiac regenerative medicine by Murata, Kozue, Ikegawa, Masaya, Minatoya, Kenji, Masumoto, Hidetoshi

“…Cardiac regenerative therapy is expected to be a promising therapeutic option for the treatment of severe cardiovascular diseases. Artificial tissues or…”
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A novel approach for the endothelialization of xenogeneic decellularized vascular tissues by human cells utilizing surface modification and dynamic culture by Ho, Wen-Jin, Kobayashi, Mako, Murata, Kozue, Hashimoto, Yoshihide, Izumi, Kenji, Kimura, Tsuyoshi, Kanemitsu, Hideo, Yamazaki, Kazuhiro, Ikeda, Tadashi, Minatoya, Kenji, Kishida, Akio, Masumoto, Hidetoshi

“…Decellularized xenogeneic vascular grafts can be used in revascularization surgeries. We have developed decellularization methods using high hydrostatic…”
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Predicted risk of heart failure pandemic due to persistent SARS-CoV-2 infection using a three-dimensional cardiac model by Murata, Kozue, Makino, Akiko, Tomonaga, Keizo, Masumoto, Hidetoshi

“…Patients with chronic cardiomyopathy may have persistent viral infections in their hearts, particularly with SARS-CoV-2, which targets the ACE2 receptor highly…”
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Advanced application of bovine intestinal epithelial cell line for evaluating regulatory effect of lactobacilli against heat-killed enterotoxigenic Escherichia coli-mediated inflammation by Takanashi, Naoya, Tomosada, Yohsuke, Villena, Julio, Murata, Kozue, Takahashi, Takuya, Chiba, Eriko, Tohno, Masanori, Shimazu, Tomoyuki, Aso, Hisashi, Suda, Yoshihito, Ikegami, Shuji, Itoh, Hiroyuki, Kawai, Yasushi, Saito, Tadao, Alvarez, Susana, Kitazawa, Haruki

“…Previously, a bovine intestinal epithelial cell line (BIE cells) was successfully established. This work hypothesized that BIE cells are useful in vitro model…”
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Bifidobacterium breve MCC-117 Induces Tolerance in Porcine Intestinal Epithelial Cells: Study of the Mechanisms Involved in the Immunoregulatory Effect by MURATA, Kozue, TOMOSADA, Yohsuke, VILLENA, Julio, CHIBA, Eriko, SHIMAZU, Tomoyuki, ASO, Hisashi, IWABUCHI, Noriyuki, XIAO, Jin-zhong, SAITO, Tadao, KITAZAWA, Haruki

“…Bifidobacterium breve MCC-117 is able to significantly reduce the expression of inflammatory cytokines in porcine intestinal epithelial (PIE) cells and to…”
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Abstract 4140645: Simultaneous Electro-Dynamic Stimulation Accelerates Maturation of Engineered Cardiac Tissue from Human Induced Pluripotent Stem Cells by Maihemuti, Wusiman, Murata, Kozue, Abulaiti, Mosha, Masumoto, Hidetoshi

“…Abstract only BACKGROUND: Electrical and dynamic stimulation are commonly used to enhance the maturation of engineered cardiac tissue (ECT) derived from…”
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Abstract 13022: Myocardial Restoration and Functional Recovery Through Transplantation of Vascularized Cardiac Microtissues Derived From Human Induced Pluripotent Stem Cells in a Rat Model of Myocardial Infarction by Hakamada, Keisuke, Murata, Kozue, Minatoya, Kenji, Masumoto, Hidetoshi

“…Abstract only Introduction: Cardiac regenerative therapy is acknowledged as a promising strategy for treating individuals suffering from severe heart failure…”
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Abstract 13757: Suppression of Ischemia-Hypoxia Reperfusion Injury in Human iPS Cell-Derived Cardiomyocytes Through Downregulation of EGR1 Mediated by miR-124-3p by Yang, Qiaoke, Murata, Kozue, Ikeda, Tadashi, Minatoya, Kenji, Masumoto, Hidetoshi

“…Abstract only Background: Ischemic heart diseases are one of the leading causes of death globally. Although timely revascularization is performed, some cases…”
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Abstract 4142206: Shear Stress-based Purification Method for Human Pluripotent Stem Cell-derived Endothelial Cells by Abulaiti, Mosha, Maihemuti, Wusiman, Murata, Kozue, Gonzalez-Teshima, Laura, Yalikun, Yaxiaer, Masumoto, Hidetoshi

“…Abstract only Background: To apply human pluripotent stem cell-derived endothelial cells (hPSC-ECs) in regenerative medicine, exploring methods for highly…”
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Abstract 4145489: Serum Proteomics Approach to Identify the ‘Hepatic Factor’ Causing Pulmonary Arteriovenous Malformations Post-Glenn Shunt by Gonzalez-Teshima, Laura, Hakamada, Keisuke, Ikeda, Tadashi, Murata, Kozue, Minatoya, Kenji, Masumoto, Hidetoshi

“…Abstract only Introduction: Pulmonary Arteriovenous Malformations (PAVMs) are a main surgical complication of second-stage palliative Glenn shunt for single…”
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Abstract 4124354: Transplantation of vascularized cardiac microtissue derived from human iPS cells improves impaired electrical conduction capacity in a porcine myocardial injury model by Kuroda, Yuki, Iida, Jun, Murata, Kozue, Kobiki, Jumpei, Minatoya, Kenji, Masumoto, Hidetoshi

“…Abstract only Background: To realize efficient regenerative medicine using human iPS cell (hiPSC)-derived cardiac tissue, it is necessary to achieve electrical…”
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Systems for the functional evaluation of human heart tissues derived from pluripotent stem cells by Murata, Kozue, Masumoto, Hidetoshi

“…Human pluripotent stem cells (hPSCs) are expected to be a promising cell source in regenerative medicine and drug discovery for the treatment of various…”
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Simultaneous electro-dynamic stimulation accelerates maturation of engineered cardiac tissues generated by human iPS cells by Maihemuti, Wusiman, Murata, Kozue, Abulaiti, Mosha, Minatoya, Kenji, Masumoto, Hidetoshi

“…Electrical and dynamic stimulation are commonly employed to enhance the maturation of engineered cardiac tissue (ECT) derived from human induced pluripotent…”
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Abstract 10172: Q Neurons-Induced Hypometabolism Ameliorates Acute Kidney Injury Associated With Renal Ischemia in a Mouse Model Mimicking Cardiovascular Surgery Requiring Circulatory Arrest by Kyo, Shoichi, Murata, Kozue, Kawatou, Masahide, Minatoya, Kenji, Sunagawa, Genshiro A, Masumoto, Hidetoshi

“…IntroductionAcute kidney injury (AKI) is a serious complication after cardiovascular surgery requiring circulatory arrest and hypothermia has been used for…”
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Abstract 14156: Promotion of Human Pluripotent Stem Cell-Engineered Cardiac Tissue Maturation by Non-Physiological Intermittent Hydrostatic Pressure by Wusiman, Maihemuti, Murata, Kozue, Iida, Jun, Hakamada, Keisuke, Sakaguchi, Akane, Mosha, Abulaiti, Saito, Yuichi, Minatoya, Kenji, Kimura, Wataru, Masumoto, Hidetoshi

“…Abstract only Background: The immaturity of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) and hPSC-engineered cardiac tissues (ECTs) hinder…”
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