Search Results - "Muraski, John A."

Activation of Notch-Mediated Protective Signaling in the Myocardium by Gude, Natalie A, Emmanuel, Gregory, Wu, Weitao, Cottage, Christopher T, Fischer, Kimberlee, Quijada, Pearl, Muraski, John A, Alvarez, Roberto, Rubio, Marta, Schaefer, Eric, Sussman, Mark A

“…The Notch network regulates multiple cellular processes, including cell fate determination, development, differentiation, proliferation, apoptosis, and…”
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Evolution of the c‐kit‐Positive Cell Response to Pathological Challenge in the Myocardium by Fransioli, Jenna, Bailey, Brandi, Gude, Natalie A., Cottage, Christopher T., Muraski, John A., Emmanuel, Gregory, Wu, Weitao, Alvarez, Roberto, Rubio, Marta, Ottolenghi, Sergio, Schaefer, Erik, Sussman, Mark A.

“…Cumulative evidence indicates that myocardium responds to growth or injury by recruitment of stem and/or progenitor cells that participate in repair and…”
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Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload by Muraski, John A, Fischer, Kimberlee M, Wu, Weitao, Cottage, Christopher T, Quijada, Pearl, Mason, Matt, Din, Shabana, Gude, Natalie, Alvarez, Roberto Jr, Rota, Marcello, Kajstura, Jan, Wang, Zeping, Schaefer, Erik, Chen, Xiongen, MacDonnel, Scott, Magnuson, Nancy, Houser, Stephen R, Anversa, Piero, Sussman, Mark A

“…Pim-1 kinase exerts potent cardioprotective effects in the myocardium downstream of AKT, but the participation of Pim-1 in cardiac hypertrophy requires…”
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Topical delivery of hyaluronic acid into skin using SPACE-peptide carriers by Chen, Ming, Gupta, Vivek, Anselmo, Aaron C., Muraski, John A., Mitragotri, Samir

“…Topical penetration of macromolecules into the skin is limited by their low permeability. Here, we report the use of a skin penetrating peptide, SPACE peptide,…”
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Topical delivery of siRNA into skin using SPACE-peptide carriers by Chen, Ming, Zakrewsky, Michael, Gupta, Vivek, Anselmo, Aaron C., Slee, Deborah H., Muraski, John A., Mitragotri, Samir

“…Short-interfering RNAs (siRNAs) offer a potential tool for the treatment of skin disorders. However, applications of siRNA for dermatological conditions are…”
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Peptides as skin penetration enhancers: Mechanisms of action by Kumar, Sunny, Zakrewsky, Michael, Chen, Ming, Menegatti, Stefano, Muraski, John A., Mitragotri, Samir

“…Skin penetrating peptides (SPPs) have garnered wide attention in recent years and emerged as a simple and effective noninvasive strategy for macromolecule…”
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Topical delivery of Cyclosporine A into the skin using SPACE-peptide by Chen, Ming, Kumar, Sunny, Anselmo, Aaron C., Gupta, Vivek, Slee, Deborah H., Muraski, John A., Mitragotri, Samir

“…Cyclosporine A (CsA) is used for the treatment of psoriasis; however systemic administration of CsA is potentially life threatening and there are long-term…”
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De Novo Design of Skin-Penetrating Peptides for Enhanced Transdermal Delivery of Peptide Drugs by Menegatti, Stefano, Zakrewsky, Michael, Kumar, Sunny, De Oliveira, Joshua Sanchez, Muraski, John A., Mitragotri, Samir

“…Skin‐penetrating peptides (SPPs) are attracting increasing attention as a non‐invasive strategy for transdermal delivery of therapeutics. The identification of…”
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Mechanistic Analysis of Cellular Internalization of a Cell- and Skin-Penetrating Peptide by Zakrewsky, Michael, Muraski, John A., Mitragotri, Samir

“…Background Keratinocytes are a targeted cell-type for treating skin disease. However, delivering drugs into the skin and keratinocytes remains challenging due…”
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Pim-1 regulates cardiomyocyte survival downstream of Akt by Sussman, Mark A, Muraski, John A, Rota, Marcello, Misao, Yu, Fransioli, Jenna, Cottage, Christopher, Gude, Natalie, Esposito, Grazia, Delucchi, Francesca, Arcarese, Michael, Alvarez, Roberto, Siddiqi, Sailay, Emmanuel, Gregory N, Wu, Weitao, Fischer, Kimberlee, Martindale, Joshua J, Glembotski, Christopher C, Leri, Annarosa, Kajstura, Jan, Magnuson, Nancy, Berns, Anton, Beretta, Remus M, Houser, Steven R, Schaefer, Erik M, Anversa, Piero

“…The serine-threonine kinases Pim-1 and Akt regulate cellular proliferation and survival. Although Akt is known to be a crucial signaling protein in the…”
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Enhanced epidermal localization of topically applied steroids using SPACE™ peptide by Kumar, Sunny, Chen, Ming, Anselmo, Aaron C., Muraski, John A., Mitragotri, Samir

“…The balance of efficacy and safety of topical corticosteroids (TCs) depends on their ability to penetrate into and be retained within the skin. Here, we…”
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Corrigendum: Pim-1 regulates cardiomyocyte survival downstream of Akt by Muraski, John A, Rota, Marcello, Misao, Yu, Fransioli, Jenna, Cottage, Christopher, Gude, Natalie, Esposito, Grazia, Delucchi, Francesca, Arcarese, Michael, Alvarez, Roberto, Siddiqi, Sailay, Emmanuel, Gregory N, Wu, Weitao, Fischer, Kimberlee, Martindale, Joshua J, Glembotski, Christopher C, Leri, Annarosa, Kajstura, Jan, Magnuson, Nancy, Berns, Anton, Beretta, Remus M, Houser, Steven R, Schaefer, Erik M, Anversa, Piero, Sussman, Mark A

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Erratum: Corrigendum: Pim-1 regulates cardiomyocyte survival downstream of Akt by Muraski, John A, Rota, Marcello, Misao, Yu, Fransioli, Jenna, Cottage, Christopher, Gude, Natalie, Esposito, Grazia, Delucchi, Francesca, Arcarese, Michael, Alvarez, Roberto, Siddiqi, Sailay, Emmanuel, Gregory N, Wu, Weitao, Fischer, Kimberlee, Martindale, Joshua J, Glembotski, Christopher C, Leri, Annarosa, Kajstura, Jan, Magnuson, Nancy, Berns, Anton, Beretta, Remus M, Houser, Steven R, Schaefer, Erik M, Anversa, Piero, Sussman, Mark A

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Correction: Corrigendum: Pim-1 regulates cardiomyocyte survival downstream of Akt by Muraski, John A, Rota, Marcello, Misao, Yu, Fransioli, Jenna, Cottage, Christopher, Gude, Natalie, Esposito, Grazia, Delucchi, Francesca, Arcarese, Michael, Alvarez, Roberto, Siddiqi, Sailay, Emmanuel, Gregory N, Wu, Weitao, Fischer, Kimberlee, Martindale, Joshua J, Glembotski, Christopher C, Leri, Annarosa, Kajstura, Jan, Magnuson, Nancy, Berns, Anton, Beretta, Remus M, Houser, Steven R, Schaefer, Erik M, Anversa, Piero, Sussman, Mark A

“…Nat. Med. 13, 1467–1475 (2007); published online 25 November 2007; corrected after print 13 February 2008. In the version of this article initially published,…”
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The cardioprotective effects of Pim-1 kinase by Muraski, John A

“…Cardioprotection through cell survival kinase signaling endures as a highly significant avenue of cardiac research. Herein we demonstrate the proto-oncogenic…”
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Experience based career education for learning disabled adolescents by Muraski, John A

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Designing Career Education Programs that Work by Muraski, John A

“…Steps in developing career education programs for learning disabled adolescents are described, and components of a successful career education program are…”
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