Search Results - "Murashima, Takashi"

Anionic phthalocyanines targeting G-quadruplexes and inhibiting telomerase activity in the presence of excessive DNA duplexes by Yaku, Hidenobu, Murashima, Takashi, Miyoshi, Daisuke, Sugimoto, Naoki

“…Anionic phthalocyanines inhibited efficiently telomerase activity even in the presence of excess double-stranded DNA (dsDNA) because of their selective binding…”
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In Vitro Assays Predictive of Telomerase Inhibitory Effect of G‑Quadruplex Ligands in Cell Nuclei by Yaku, Hidenobu, Murashima, Takashi, Miyoshi, Daisuke, Sugimoto, Naoki

“…G-quadruplex-binding and telomerase-inhibiting capacities of G-quadruplex ligands were examined under a cell nuclei-mimicking condition including excess…”
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A mRNA-Responsive G-Quadruplex-Based Drug Release System by Yaku, Hidenobu, Murashima, Takashi, Miyoshi, Daisuke, Sugimoto, Naoki

“…G-quadruplex-based drug delivery carriers (GDDCs) were designed to capture and release a telomerase inhibitor in response to a target mRNA. Hybridization…”
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Study on effects of molecular crowding on G-quadruplex-ligand binding and ligand-mediated telomerase inhibition by Yaku, Hidenobu, Murashima, Takashi, Tateishi-Karimata, Hisae, Nakano, Shu-ichi, Miyoshi, Daisuke, Sugimoto, Naoki

“…The telomere G-quadruplex-binding and telomerase-inhibiting capacity of two cationic (TMPyP4 and PIPER) and two anionic (phthalocyanine and Hemin)…”
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A highly sensitive telomerase activity assay that eliminates false-negative results caused by PCR inhibitors by Yaku, Hidenobu, Murashima, Takashi, Miyoshi, Daisuke, Sugimoto, Naoki

“…An assay for telomerase activity based on asymmetric polymerase chain reaction (A-PCR) on magnetic beads (MBs) and subsequent application of cycling probe…”
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A simple "add and measure" FRET-based telomeric tandem repeat sequence detection and telomerase assay method by Kawamura, Koji, Yaku, Hidenobu, Miyoshi, Daisuke, Murashima, Takashi

“…A simple and sensitive method for measuring telomeric tandem repeat DNA and telomerase activity based on fluorescence resonance energy transfer (FRET) with a…”
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Molecular Imprinting under Molecular Crowding Conditions:  An Aid to the Synthesis of a High-Capacity Polymeric Sorbent for Triazine Herbicides by Matsui, Jun, Goji, Shou, Murashima, Takashi, Miyoshi, Daisuke, Komai, Satoshi, Shigeyasu, Aiko, Kushida, Takuho, Miyazawa, Toshifumi, Yamada, Takashi, Tamaki, Katsuyuki, Sugimoto, Naoki

“…Molecular crowding, an important feature of the molecular environments in biological cells, was applied to the synthesis of antibody-mimic polymers selective…”
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Mechanistic Study on Microstructural Tuning of Metal Nanoparticle/Polymer Composite Thin Layers: Hydrogenation and Decomposition of Polyimide Matrices Catalyzed by Embedded Nickel Nanoparticles by Akamatsu, Kensuke, Fujii, Maki, Tsuruoka, Takaaki, Nakano, Shu-ichi, Murashima, Takashi, Nawafune, Hidemi

“…Magnetic composite nanostructures composed of a dielectric matrix containing magnetic nanoparticles offer opportunities for the fabrication of next-generation…”
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Facile One-Pot Synthesis of Aromatic and Heteroaromatic Sulfonamides by Pandya, Rina, Murashima, Takashi, Tedeschi, Livio, Barrett, Anthony G. M

“…A series of arene and heteroarene sulfonamides were prepared in one vessel from aryl and heteroaryl bromides via conversion into the corresponding Grignard…”
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Secondary alcohols act as better nucleophiles than primary alcohols in the lipase-catalyzed regioselective deacylation of dihydroxybenzenes acylated at both phenolic hydroxyls by Miyazawa, Toshifumi, Hamada, Manabu, Morimoto, Ryohei, Murashima, Takashi, Yamada, Takashi

“…Candida antarctica lipase B (CAL-B) was found to be highly regioselective as well as active in the deacylation of resorcinols and hydroquinones acylated at…”
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Highly regioselective propanoylation of dihydroxybenzenes mediated by Candida antarctica lipase B in organic solvents by Miyazawa, Toshifumi, Hamada, Manabu, Morimoto, Ryohei, Murashima, Takashi, Yamada, Takashi

“…Candida antarctica lipase B (CAL-B) was found to be a highly active biocatalyst for the direct acylation of the phenolic hydroxyls of substituted hydroquinones…”
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Synthesis, structure and thermal stability of fully hydrophobic porphyrin–DNA conjugates by Murashima, Takashi, Hayata, Kazuyuki, Saiki, Yumi, Matsui, Jun, Miyoshi, Daisuke, Yamada, Takashi, Miyazawa, Toshifumi, Sugimoto, Naoki

“…The DNAs modified with tetraphenyl porphyrin at the center of 13mer oligonucleotide were synthesized using phosphoramidite chemistry and automated DNA…”
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Peptide synthesis using carbamoylmethyl esters as acyl donors mediated by Bacillus amyloliquefaciens protease by Miyazawa, Toshifumi, Shindo, Tadamichi, Murashima, Takashi, Yamada, Takashi

“…Bacillus amyloliquefaciens protease-catalyzed peptide bond formation was investigated using the carbamoylmethyl (Cam) ester as the acyl donor. A series of…”
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Phthalocyanines: a new class of G-quadruplex-ligands with many potential applications by Yaku, Hidenobu, Fujimoto, Takeshi, Murashima, Takashi, Miyoshi, Daisuke, Sugimoto, Naoki

“…A G-quadruplex is a four-stranded DNA structure featuring stacked guanine tetrads, G-quartets. Formation of a G-quadruplex in telomere DNA can inhibit…”
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A New Synthesis of Benzoporphyrins Using 4,7-Dihydro-4,7-ethano-2H-isoindole as an Isoindole Equivalent by Ono, Noboru, Ito, Satoshi, Ochi, Naoyuki, Murashima, Takashi, Uno, Hidemitsu

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Resolution of non-protein amino acids via Carica papaya lipase-catalyzed enantioselective transesterification by Miyazawa, Toshifumi, Onishi, Kazuki, Murashima, Takashi, Yamada, Takashi, Tsai, Shau-Wei

“…Carica papaya lipase-catalyzed transesterification of the 2,2,2-trifluoroethyl esters of N-benzyloxycarbonylated dl-amino acids carrying aliphatic side chains…”
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Development of a Basic Formation Control System for Heterogeneous Autonomous Marine Vehicles and its Sea Trials in Suruga Bay by Okamoto, Akihiro, Kim, Kangsoo, Sasano, Masahiko, Sato, Takumi, Inaba, Shogo, Kondo, Satoshi, Matsumoto, Hiroshi, Murashima, Takashi, Shimura, Takuya, Fujiwara, Toshifumi, Osawa, Hiroyuki

“…The National Maritime Research Institute of Japan has been conducting research on developing seafloor survey technology using multiple autonomous underwater…”
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Cationic Porphyrin Induced a Telomeric DNA to G-Quadruplex Form in Water by Murashima, Takashi, Sakiyama, Daichi, Miyoshi, Daisuke, Kuriyama, Masanori, Yamada, Takashi, Miyazawa, Toshifumi, Sugimoto, Naoki

“…The formation of the DNA G-quadruplex is induced by the addition of a novel porphyrin carrying four cationic tethers. Circular dichroism spectroscopy reveals…”
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Specific binding of anionic porphyrin and phthalocyanine to the G-quadruplex with a variety of in vitro and in vivo applications by Yaku, Hidenobu, Murashima, Takashi, Miyoshi, Daisuke, Sugimoto, Naoki

“…The G-quadruplex, a four-stranded DNA structure with stacked guanine tetrads (G-quartets), has recently been attracting attention because of its critical roles…”
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A New Synthesis of Functional Dyes from 2-Acenaphtho[1,2-c]pyrrole by Ono, Noboru, Yamamoto, Takanori, Shimada, Naomi, Kuroki, Kenji, Wada, Mitsuo, Utsunomiya, Ryouhei, Yano, Tomoko, Uno, Hidemitsu, Murashima, Takashi

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