Search Results - "Murase, Sachiko"

Impaired Focal Adhesion Kinase-Grb2 Interaction during Elevated Activity in Hippocampal Neurons by Murase, Sachiko

“…Excitatory/inhibitory imbalances are implicated in many neurological disorders. Previously, we showed that chronically elevated network activity induces…”
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Light reintroduction after dark exposure reactivates plasticity in adults via perisynaptic activation of MMP-9 by Murase, Sachiko, Lantz, Crystal L, Quinlan, Elizabeth M

“…The sensitivity of ocular dominance to regulation by monocular deprivation is the canonical model of plasticity confined to a critical period. However, we have…”
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Neuregulin-Dependent Regulation of Fast-Spiking Interneuron Excitability Controls the Timing of the Critical Period by Gu, Yu, Tran, Trinh, Murase, Sachiko, Borrell, Andrew, Kirkwood, Alfredo, Quinlan, Elizabeth M

“…Maturation of excitatory drive onto fast-spiking interneurons (FS INs) in the visual cortex has been implicated in the control of the timing of the critical…”
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Homeostatic regulation of perisynaptic matrix metalloproteinase 9 (MMP9) activity in the amblyopic visual cortex by Murase, Sachiko, Winkowski, Dan, Liu, Ji, Kanold, Patrick O, Quinlan, Elizabeth M

“…Dark exposure (DE) followed by light reintroduction (LRx) reactivates robust synaptic plasticity in adult mouse primary visual cortex (V1), which allows…”
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Neuronal activity-dependent STAT3 localization to nucleus is dependent on Tyr-705 and Ser-727 phosphorylation in rat hippocampal neurons by Murase, Sachiko, McKay, Ronald D.

“…Signal transducer and activator of transcription 3 (STAT3) dramatically increases during the first post‐natal week, and supports the survival of mature…”
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A New Model for Developmental Neuronal Death and Excitatory/Inhibitory Balance in Hippocampus by Murase, Sachiko

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Matrix Metalloproteinase-9 Regulates Survival of Neurons in Newborn Hippocampus by Murase, Sachiko, McKay, Ronald D.

“…The number of neurons in the adult rodent brain is strongly influenced by events in early postnatal life that eliminate approximately half of the neurons…”
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Chronic Monocular Deprivation Reveals MMP9-Dependent and -Independent Aspects of Murine Visual System Plasticity by Murase, Sachiko, Robertson, Sarah E, Lantz, Crystal L, Liu, Ji, Winkowski, Daniel E, Quinlan, Elizabeth M

“…The deletion of matrix metalloproteinase MMP9 is combined here with chronic monocular deprivation (cMD) to identify the contributions of this proteinase to…”
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Immunological validation of the pharmacological and anti‐allergic action of glycyrrhetinic acid from Glycyrrhizae Radix by Hisaka, Shinsuke, Murase, Sachiko, Kishi, Hayato, Nose, Mitsuhiko

“…ABSTRACT Aim Glycyrrhetinic acid (GA) is an important and active metabolite derived from glycyrrhizin (GL) in Glycyrrhizae Radix (GR) that induces…”
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A Specific Survival Response in Dopamine Neurons at Most Risk in Parkinson's Disease by Murase, Sachiko, McKay, Ronald D

“…The specific expression of fibroblast growth factor 20 (FGF-20) in the adult substantia nigra and the association between FGF-20 mutations and Parkinson's…”
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The role of cell adhesion molecules in synaptic plasticity and memory by Murase, Sachiko, Schuman, Erin M

“…Studies in the past few years suggest that cell adhesion molecules may play signaling as well as structural roles at adult synapses during plasticity. The…”
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Signal Transducer and Activator of Transcription 3 (STAT3) Degradation by Proteasome Controls a Developmental Switch in Neurotrophin Dependence by Murase, Sachiko

“…Neonatal brains develop through a program that eliminates about half of the neurons. During this period, neurons depend on neurotrophins for their survival…”
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Cadherins and synaptic plasticity: activity-dependent cyclin-dependent kinase 5 regulation of synaptic β-catenin-cadherin interactions by Schuman, Erin M., Murase, Sachiko

“…Cyclin-dependent kinase 5 (Cdk5)/p35 kinase activity is known to decrease the affinity of β-catenin for cadherin in developing cortical neurons. Our recent…”
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A New Model for Developmental Neuronal Death and Excitatory/Inhibitory Balance in Hippocampus by Murase, Sachiko

“…The nervous system develops through a program that produces neurons in excess and then eliminates approximately half during a period of naturally occurring…”
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Mutation Analysis of Cadherin-4 Reveals Amino Acid Residues of EC1 Important for the Structure and Function by Kitagawa, Michihiro, Natori, Michiya, Murase, Sachiko, Hirano, Shinji, Taketani, Shigeru, Suzuki, Shintaro T.

“…To clarify the structural basis of the cell adhesion activity of cadherins, we examined the effects of point mutations of well-conserved amino acid residues in…”
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Neuronal activity‐dependent STAT 3 localization to nucleus is dependent on Tyr‐705 and Ser‐727 phosphorylation in rat hippocampal neurons by Murase, Sachiko, McKay, Ronald D.

“…Abstract Signal transducer and activator of transcription 3 ( STAT 3) dramatically increases during the first post‐natal week, and supports the survival of…”
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All-or-none disconnection of pyramidal inputs onto parvalbumin-positive interneurons gates ocular dominance plasticity by Severin, Daniel, Hong, Su Z., Roh, Seung-Eon, Huang, Shiyong, Zhou, Jiechao, Bridi, Michelle C. D., Hong, Ingie, Murase, Sachiko, Robertson, Sarah, Haberman, Rebecca P., Huganir, Richard L., Gallagher, Michela, Quinlan, Elizabeth M., Worley, Paul, Kirkwood, Alfredo

“…Disinhibition is an obligatory initial step in the remodeling of cortical circuits by sensory experience. Our investigation on disinhibitory mechanisms in the…”
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In the newborn hippocampus, neurotrophin-dependent survival requires spontaneous activity and integrin signaling by Murase, Sachiko, Owens, David F, McKay, Ronald D

“…The nervous system develops through a program that first produces neurons in excess and then eliminates as many as half in a specific period of early postnatal…”
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Lateral Clustering of Cadherin-4 without Homophilic Interaction: Possible Involvement in the Concentration Process at Cell–Cell Adhesion Sites as Well as in the Cell Adhesion Activity by Murase, Sachiko, Hirano, Shinji, Wang, Xiaopeng, Kitagawa, Michihiro, Natori, Michiya, Taketani, Shigeru, Suzuki, Shintaro T.

“…It is thought that the concentration of classic cadherins at cell–cell adhesion sites is essential for generating strong cell–cell adhesion activity, but the…”
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Matrix Metalloproteinase-9 Regulates Neuronal Circuit Development and Excitability by Murase, Sachiko, Lantz, Crystal L., Kim, Eunyoung, Gupta, Nitin, Higgins, Richard, Stopfer, Mark, Hoffman, Dax A., Quinlan, Elizabeth M.

“…In early postnatal development, naturally occurring cell death, dendritic outgrowth, and synaptogenesis sculpt neuronal ensembles into functional neuronal…”
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