Search Results - "Murase, Remi"

Secreted Phospholipase PLA2G2D Contributes to Metabolic Health by Mobilizing ω3 Polyunsaturated Fatty Acids in WAT by Sato, Hiroyasu, Taketomi, Yoshitaka, Miki, Yoshimi, Murase, Remi, Yamamoto, Kei, Murakami, Makoto

“…Polyunsaturated fatty acids (PUFAs) confer health benefits by preventing inflammation and obesity and by increasing thermogenesis in brown and beige…”
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Group X Secreted Phospholipase A2 Releases ω3 Polyunsaturated Fatty Acids, Suppresses Colitis, and Promotes Sperm Fertility by Murase, Remi, Sato, Hiroyasu, Yamamoto, Kei, Ushida, Ayako, Nishito, Yasumasa, Ikeda, Kazutaka, Kobayashi, Tetsuyuki, Yamamoto, Toshinori, Taketomi, Yoshitaka, Murakami, Makoto

“…Within the secreted phospholipase A2 (sPLA2) family, group X sPLA2 (sPLA2-X) has the highest capacity to hydrolyze cellular membranes and has long been thought…”
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Anti-inflammatory effects of new catechin derivatives in a hapten-induced mouse contact dermatitis model by Nakano, Eriko, Kamei, Daisuke, Murase, Remi, Taki, Iori, Karasawa, Koji, Fukuhara, Kiyoshi, Iwai, Shinichi

“…Contact dermatitis is a common skin disease, with various treatments available to dermatologists. According to general guidelines, the first line of treatment…”
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Group X phospholipase A2 links colonic lipid homeostasis to systemic metabolism via host-microbiota interaction by Sato, Hiroyasu, Taketomi, Yoshitaka, Murase, Remi, Park, Jonguk, Hosomi, Koji, Sanada, Takayuki Jujo, Mizuguchi, Kenji, Arita, Makoto, Kunisawa, Jun, Murakami, Makoto

“…The gut microbiota influences physiological functions of the host, ranging from the maintenance of local gut homeostasis to systemic immunity and metabolism…”
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Group IID, IIE, IIF and III secreted phospholipase A2s by Murakami, Makoto, Miki, Yoshimi, Sato, Hiroyasu, Murase, Remi, Taketomi, Yoshitaka, Yamamoto, Kei

“…Among the 11 members of the secreted phospholipase A2 (sPLA2) family, group IID, IIE, IIF and III sPLA2s (sPLA2-IID, -IIE, -IIF and -III, respectively) are…”
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Associations of HLA-C01:02 and HLA-B46:01 with regorafenib-induced erythema multiforme in Japanese patients with metastatic colorectal cancer by Fujita, Ken-Ichi, Matsumoto, Natsumi, Murase, Remi, Takeshima, Kosuke, Ishida, Hiroo, Kubota, Yutaro

“…Regorafenib improves the survival of patients with metastatic colorectal cancer (mCRC); however, it is also characterized by detrimental dermal side effects…”
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Mast Cell-Specific Deletion of Group III Secreted Phospholipase A2 Impairs Mast Cell Maturation and Functions by Taketomi, Yoshitaka, Endo, Yuki, Higashi, Takayoshi, Murase, Remi, Ono, Tomio, Taya, Choji, Kobayashi, Tetsuyuki, Murakami, Makoto

“…Tissue-resident mast cells (MCs) have important roles in IgE-associated and -independent allergic reactions. Although microenvironmental alterations in MC…”
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Effect of intraoral antioxidative capacity in orengedokuto by Nishijima, Hiroaki, Takamatsu, Satoshi, Satoh, Kazue, Murase, Remi, Taki, Iori, Kamei, Daisuke, Kawazoe, Kazuyoshi, Nemoto, Yukio, Iwai, Shinichi

“…ABSTRACT Aim The aim of this study is to clarify the antioxidative effects of orengedokuto (OGT) and its crude drug components in the human oral cavity. Method…”
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Association of VEGFA and CCL4L2 polymorphisms with hand-foot skin reaction and survival of regorafenib in Japanese patients with colorectal cancer by Ono, Koutaro, Murase, Remi, Matsumoto, Natsumi, Kubota, Yutaro, Ishida, Hiroo, Fujita, Ken-ichi

“…Purpose Treatment with regorafenib, which inhibits vascular endothelial growth factor (VEGF) receptor, frequently results in hand-foot skin reaction (HFSR),…”
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Group IID, IIE, IIF and III secreted phospholipase A 2 s by Murakami, Makoto, Miki, Yoshimi, Sato, Hiroyasu, Murase, Remi, Taketomi, Yoshitaka, Yamamoto, Kei

“…Among the 11 members of the secreted phospholipase A (sPLA ) family, group IID, IIE, IIF and III sPLA s (sPLA -IID, -IIE, -IIF and -III, respectively) are…”
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A polymorphism in ABCA2 is associated with neutropenia induced by capecitabine in Japanese patients with colorectal cancer by Shibata, Yukitaka, Matsumoto, Natsumi, Murase, Remi, Kubota, Yutaro, Ishida, Hiroo, Shimada, Ken, Fujita, Ken-ichi

“…Purpose Capecitabine is a prodrug that converts to 5-fluorouracil (5-FU) in three steps. A previous study showed that ABCA2 rs2271862 (C > T) and ABCG5…”
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Investigation of Hypersensitivity Reactions in Carboplatin Desensitization Therapy by Shibata, Naoki, Kawakami, Kazuyoshi, Hisanori, Shimizu, Kobayashi, Kazuo, Yunokawa, Mayu, Kanao, Hiroyuki, Taki, Iori, Murase, Remi, Kamei, Daisuke, Yamaguchi, Masakazu

“…Carboplatin is a key drug in the treatment of ovarian cancer, but hypersensitivity reactions (HSRs) may occur with repeated use. Thirty-seven ovarian cancer…”
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Group III phospholipase A2 promotes colitis and colorectal cancer by Murase, Remi, Taketomi, Yoshitaka, Miki, Yoshimi, Nishito, Yasumasa, Saito, Moe, Fukami, Kiyoko, Yamamoto, Kei, Murakami, Makoto

“…Lipid mediators play pivotal roles in colorectal cancer and colitis, but only a limited member of the phospholipase A 2 (PLA 2 ) subtypes, which lie upstream…”
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Association Between ABCC2 -24C>T and Nab-Paclitaxel-induced Peripheral Neuropathy in Japanese Patients With Pancreatic Cancer by Nakayama, Hana, Ishida, Hiroo, Iidaka, Masanori, Kato, Shoko, Nakatani, Kei, Nakayama, Akihiro, Noguchi, Toshihiro, Nishihara, Shigetoshi, Oikawa, Shu, Usami, Tomono, Mitsui, Yuta, Ishii, Y U, Toshima, Hirokazu, Kobayashi, Kouji, Murase, Remi, Matsumoto, Natsumi, Suzuki, Kosuke, Shimada, Ken, Yoshida, Hitoshi, Fujita, Ken-Ichi

“…Nab-paclitaxel is used to treat patients with pancreatic cancer. However, it frequently induces peripheral neuropathy. Notably, pharmacokinetic factors may be…”
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Group X phospholipase A 2 links colonic lipid homeostasis to systemic metabolism via host-microbiota interaction by Sato, Hiroyasu, Taketomi, Yoshitaka, Murase, Remi, Park, Jonguk, Hosomi, Koji, Sanada, Takayuki Jujo, Mizuguchi, Kenji, Arita, Makoto, Kunisawa, Jun, Murakami, Makoto

“…The gut microbiota influences physiological functions of the host, ranging from the maintenance of local gut homeostasis to systemic immunity and metabolism…”
Get full text

Mast Cell-Specific Deletion of Group III Secreted Phospholipase A 2 Impairs Mast Cell Maturation and Functions by Taketomi, Yoshitaka, Endo, Yuki, Higashi, Takayoshi, Murase, Remi, Ono, Tomio, Taya, Choji, Kobayashi, Tetsuyuki, Murakami, Makoto

“…Tissue-resident mast cells (MCs) have important roles in IgE-associated and -independent allergic reactions. Although microenvironmental alterations in MC…”
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Group III phospholipase A 2 promotes colitis and colorectal cancer by Murase, Remi, Taketomi, Yoshitaka, Miki, Yoshimi, Nishito, Yasumasa, Saito, Moe, Fukami, Kiyoko, Yamamoto, Kei, Murakami, Makoto

“…Lipid mediators play pivotal roles in colorectal cancer and colitis, but only a limited member of the phospholipase A (PLA ) subtypes, which lie upstream of…”
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Mast cell maturation is driven via a group III phospholipase [A.sub.2]-prostaglandin [D.sub.2]-DP1 receptor paracrine axis by Taketomi, Yoshitaka, Ueno, Noriko, Kojima, Takumi, Sato, Hiroyasu, Murase, Remi, Yamamoto, Kei, Tanaka, Satoshi, Sakanaka, Mariko, Nakamura, Masanori, Nishito, Yasumasa, Kawana, Momoko, Kambe, Naotomo, Ikeda, Kazutaka, Taguchi, Ryo, Nakamizo, Satoshi, Kabashima, Kenji, Gelb, Michael H, Arita, Makoto, Yokomizo, Takehiko, Nakamura, Motonao, Watanabe, Kikuko, Hirai, Hiroyuki, Nakamura, Masataka, Okayama, Yoshimichi, Ra, Chisei, Aritake, Kosuke, Urade, Yoshihiro, Morimoto, Kazushi, Sugimoto, Yukihiko, Shimizu, Takao, Narumiya, Shuh, Hara, Shuntaro, Murakami, Makoto

“…Microenvironment-based alterations in phenotypes of mast cells influence the susceptibility to anaphylaxis, yet the mechanisms underlying proper maturation of…”
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Mast cell maturation is driven via a group III phospholipase A sub(2)-prostaglandin D sub(2)-DP1 receptor paracrine axis by Taketomi, Yoshitaka, Ueno, Noriko, Kojima, Takumi, Sato, Hiroyasu, Murase, Remi, Yamamoto, Kei, Tanaka, Satoshi, Sakanaka, Mariko, Nakamura, Masanori, Nishito, Yasumasa, Kawana, Momoko, Kambe, Naotomo, Ikeda, Kazutaka, Taguchi, Ryo, Nakamizo, Satoshi, Kabashima, Kenji, Gelb, Michael H, Arita, Makoto, Yokomizo, Takehiko, Nakamura, Motonao, Watanabe, Kikuko, Hirai, Hiroyuki, Nakamura, Masataka, Okayama, Yoshimichi, Ra, Chisei, Aritake, Kosuke, Urade, Yoshihiro, Morimoto, Kazushi, Sugimoto, Yukihiko, Shimizu, Takao, Narumiya, Shuh, Hara, Shuntaro, Murakami, Makoto

“…Microenvironment-based alterations in phenotypes of mast cells influence the susceptibility to anaphylaxis, yet the mechanisms underlying proper maturation of…”
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Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2–DP1 receptor paracrine axis by Taketomi, Yoshitaka, Ueno, Noriko, Kojima, Takumi, Sato, Hiroyasu, Murase, Remi, Yamamoto, Kei, Tanaka, Satoshi, Sakanaka, Mariko, Nakamura, Masanori, Nishito, Yasumasa, Kawana, Momoko, Kambe, Naotomo, Ikeda, Kazutaka, Taguchi, Ryo, Nakamizo, Satoshi, Kabashima, Kenji, Gelb, Michael H, Arita, Makoto, Yokomizo, Takehiko, Nakamura, Motonao, Watanabe, Kikuko, Hirai, Hiroyuki, Nakamura, Masataka, Okayama, Yoshimichi, Ra, Chisei, Aritake, Kosuke, Urade, Yoshihiro, Morimoto, Kazushi, Sugimoto, Yukihiko, Shimizu, Takao, Narumiya, Shuh, Hara, Shuntaro, Murakami, Makoto

“…The mechanisms controlling maturation of mast cells toward an anaphylaxis-sensitive phenotype remain unclear. Murakami and colleagues show that PLA2G3, a…”
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