Search Results - "Murasawa, Shingo"
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Eosinophil counts can be a predictive marker of immune checkpoint inhibitor-induced secondary adrenal insufficiency: a retrospective cohort study
Published in Scientific reports (25-01-2022)“…Immune checkpoint inhibitors (ICIs) treatment can result in endocrine immune-related adverse events (irAEs), including pituitary dysfunction. Quick diagnosis…”
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Growth differentiation factor-15 modulates adrenocorticotropic hormone synthesis in murine AtT-20 corticotroph cells
Published in Peptides (New York, N.Y. : 1980) (01-09-2022)“…Growth differentiation factor-15 (GDF15) is a stress-responsive cytokine that plays important roles in regulation of inflammatory responses, cell growth, and…”
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A case of successful treatment with repeated segmental embolization for downhill esophageal varices caused by giant goiter
Published in Internal Medicine (2024)“…Downhill esophageal varices often develop because of venous hypertension caused by either superior vena cava obstruction or compression. We herein present a…”
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Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report
Published in BMC neurology (15-12-2022)“…Neurological symptoms and radiographic abnormalities may remain in a small proportion of patients with metronidazole-induced encephalopathy (MIE). Although…”
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Inhibitory effects of trichostatin A on adrenocorticotropic hormone production and proliferation of corticotroph tumor AtT-20 cells
Published in ENDOCRINE JOURNAL (2015)“…Cushing’s disease is primarily caused by adrenocorticotropic hormone (ACTH)-producing pituitary adenomas. Pituitary tumor-transforming gene 1 (PTTG1)…”
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Inhibitory effects of SOM230 on adrenocorticotropic hormone production and corticotroph tumor cell proliferation in vitro and in vivo
Published in Molecular and cellular endocrinology (25-08-2014)“…•SOM230 suppressed ACTH synthesis and secretion in corticotroph tumor cells.•SOM230 inhibited corticotroph tumor cell proliferation.•SSTR5 knockdown inhibited…”
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Inhibition of heat shock protein 90 decreases ACTH production and cell proliferation in AtT-20 cells
Published in Pituitary (01-08-2015)“…Purpose Cushing’s disease is primarily caused by adrenocorticotropic hormone (ACTH)-producing pituitary adenomas. If excision of the tumor from the pituitary,…”
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Aphidicolin inhibits cell proliferation via the p53-GADD45β pathway in AtT-20 cells
Published in Endocrine Journal (2015)“…Cushing’s disease is primarily caused by pituitary corticotroph adenomas, which autonomically secrete adrenocorticotropic hormone (ACTH). ACTH production may…”
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Action of glucagon-like peptide 1 and glucose levels on corticotropin-releasing factor and vasopressin gene expression in rat hypothalamic 4B cells
Published in Molecular and cellular endocrinology (15-10-2012)“…► Direct regulation of CRF and AVP genes by GLP-1 was observed in hypothalamic 4B cells. ► GLP-1 contributes to stress responses through activation of CRF and…”
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The Evaluation of Adrenal Function in Two Cases of Hypocortisolism Accompanied by Liver Cirrhosis
Published in Internal Medicine (01-01-2016)“…Adrenal insufficiency may occur in patients with liver cirrhosis. The assessment of hypothalamus-pituitary-adrenal function is important in such patients, but…”
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Dexamethasone stimulates the expression of ghrelin and its receptor in rat hypothalamic 4B cells
Published in Regulatory peptides (10-02-2012)“…Growth hormone (GH)-releasing peptides (GHRPs) are synthetic peptides that strongly induce GH release. GHRPs act via a specific receptor, the GHRP receptor…”
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Evaluation of the (1–24) adrenocorticotropin stimulation test for the diagnosis of primary aldosteronism
Published in Journal of the renin-angiotensin-aldosterone system (27-02-2016)“…Objective: The purpose of this study was to investigate the diagnostic power of the adrenocorticotropin (ACTH) stimulation test in patients with primary…”
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Acute mesenteric ischemia and hepatic infarction after treatment of ectopic Cushing’s syndrome
Published in Endocrinology, diabetes & metabolism case reports (28-02-2017)“…Summary Patients with Cushing’s syndrome and excess exogenous glucocorticoids have an increased risk for venous thromboembolism, as well as arterial thrombi…”
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A Case Of Cystic Pheochromocytoma With Hypertension And Headaches Mimicking A Large Pancreatic Cystic Tumor
Published in AACE clinical case reports (2017)“…Objective: Cystic pheochromocytomas can become enlarged without abdominal symptoms and can potentially be confused with other abdominal cystic tumors.Methods:…”
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Aphidicolin inhibits cell proliferation via the p53-GADD45β pathway in AtT-20 cells
Published in ENDOCRINE JOURNAL (01-07-2015)“…[Abstract. ] Cushing's disease is primarily caused by pituitary corticotroph adenomas, which autonomically secrete adrenocorticotropic hormone (ACTH). ACTH…”
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A Case of Nonalcoholic Steatohepatitis in a Cured Acromegalic Patient With Severe Growth Hormone Deficiency
Published in AACE clinical case reports (01-01-2016)“…Objective: Acromegaly is associated with metabolic and neoplastic complications, but successful treatment of acromegaly can sometimes result in growth hormone…”
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Fulminant Type 1 Diabetes in an 81-Year-Old Male with Rhabdomyolysis-Induced Acute Kidney Injury Successfully Withdrawn from Hemodialysis: A Case Report
Published in AACE clinical case reports (2015)“…Objective: Fulminant type 1 diabetes mellitus (FT1DM), a distinct subtype of type 1 diabetes, is characterized by a rapid onset of severe hyperglycemia and…”
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Vasopressin Expressed in Hypothalamic CRF Neurons Causes Impaired Water Diuresis in Secondary Adrenal Insufficiency
Published in Endocrinology (Philadelphia) (01-08-2023)“…Abstract Patients with secondary adrenal insufficiency can present with impaired free water excretion and hyponatremia, which is due to the enhanced secretion…”
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Biochemical Evaluation by Confirmatory Tests after Unilateral Adrenalectomy for Primary Aldosteronism
Published in Journal of the renin-angiotensin-aldosterone system (01-01-2023)“…Primary aldosteronism (PA) is the most common cause of endocrine hypertension. Unilateral PA can be cured using unilateral adrenalectomy (Adx). PA surgery…”
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