Search Results - "Murani, Eduard"

Exploration of genotype-by-environment interactions affecting gene expression responses in porcine immune cells by Murani, Eduard, Hadlich, Frieder

“…As one of the keys to healthy performance, robustness of farm animals is gaining importance, and with this comes increasing interest in genetic dissection of…”
Get full text

Glucocorticoid receptor hypersensitivity enhances inflammatory signaling and inhibits cell cycle progression in porcine PBMCs by Li, Zhiwei, Hadlich, Frieder, Wimmers, Klaus, Murani, Eduard

“…The consequences of glucocorticoid receptor (GR) hypersensitivity during infection have so far received little attention. We previously discovered that a…”
Get full text

Epigenome-wide skeletal muscle DNA methylation profiles at the background of distinct metabolic types and ryanodine receptor variation in pigs by Ponsuksili, Siriluck, Trakooljul, Nares, Basavaraj, Sajjanar, Hadlich, Frieder, Murani, Eduard, Wimmers, Klaus

“…Epigenetic variation may result from selection for complex traits related to metabolic processes or appear in the course of adaptation to mediate responses to…”
Get full text

DNA methylation landscapes from pig’s limbic structures underline regulatory mechanisms relevant for brain plasticity by Perdomo-Sabogal, Alvaro, Trakooljul, Nares, Hadlich, Frieder, Murani, Eduard, Wimmers, Klaus, Ponsuksili, Siriluck

“…Epigenetic dynamics are essential for reconciling stress-induced responses in neuro-endocrine routes between the limbic brain and adrenal gland. CpG…”
Get full text

MicroRNAs Regulate Cellular ATP Levels by Targeting Mitochondrial Energy Metabolism Genes during C2C12 Myoblast Differentiation by Siengdee, Puntita, Trakooljul, Nares, Murani, Eduard, Schwerin, Manfred, Wimmers, Klaus, Ponsuksili, Siriluck

“…In our previous study, we identified an miRNA regulatory network involved in energy metabolism in porcine muscle. To better understand the involvement of…”
Get full text

Editorial: Genotype-by-environment interaction in farm animals: from measuring to understanding by Murani, Eduard, Gilbert, Hélène, Rauw, Wendy M.

Get full text

Identification of the Key Molecular Drivers of Phosphorus Utilization Based on Host miRNA-mRNA and Gut Microbiome Interactions by Ponsuksili, Siriluck, Reyer, Henry, Hadlich, Frieder, Weber, Frank, Trakooljul, Nares, Oster, Michael, Siengdee, Puntita, Muráni, Eduard, Rodehutscord, Markus, Camarinha-Silva, Amélia, Bennewitz, Jörn, Wimmers, Klaus

“…Phosphorus is an essential mineral for all living organisms and a limited resource worldwide. Variation and heritability of phosphorus utilization (PU) traits…”
Get full text

Single- and Bayesian Multi-Marker Genome-Wide Association for Haematological Parameters in Pigs by Ponsuksili, Siriluck, Reyer, Henry, Trakooljul, Nares, Murani, Eduard, Wimmers, Klaus

“…Haematological traits are important traits that show associations with immune and metabolic status, as well as diseases in humans and animals. Mapping genome…”
Get full text

Changes in the N-glycosylation of porcine immune globulin G during postnatal development by Zlatina, Kristina, Isernhagen, Lisa, Galuska, Christina E, Murani, Eduard, Galuska, Sebastian P

“…N-glycosylation influences the effectiveness of immune globulin G (IgG) and thus the immunological downstream responses of immune cells. This impact arises…”
Get full text

Genetic Contribution to Variation in Blood Calcium, Phosphorus, and Alkaline Phosphatase Activity in Pigs by Reyer, Henry, Oster, Michael, Wittenburg, Dörte, Murani, Eduard, Ponsuksili, Siriluck, Wimmers, Klaus

“…Blood values of calcium (Ca), inorganic phosphorus (IP), and alkaline phosphatase activity (ALP) are valuable indicators for mineral status and bone…”
Get full text

Transcriptome analysis of porcine PBMCs reveals lipopolysaccharide-induced immunomodulatory responses and crosstalk of immune and glucocorticoid receptor signaling by Li, Zhiwei, Trakooljul, Nares, Hadlich, Frieder, Ponsuksili, Siriluck, Wimmers, Klaus, Murani, Eduard

“…The current level of knowledge on transcriptome responses triggered by endotoxins and glucocorticoids in immune cells in pigs is limited. Therefore, in the…”
Get full text

Transcriptome Responses to Dexamethasone Depending on Dose and Glucocorticoid Receptor Sensitivity in the Liver by Murani, Eduard, Trakooljul, Nares, Hadlich, Frieder, Ponsuksili, Siriluck, Wimmers, Klaus

“…Tissue sensitivity to glucocorticoids is a key factor dictating outcome of their homeostatic and therapeutic action, whereby liver represents one of the major…”
Get full text

SINE jumping contributes to large-scale polymorphisms in the pig genomes by Chen, Cai, D'Alessandro, Enrico, Murani, Eduard, Zheng, Yao, Giosa, Domenico, Yang, Naisu, Wang, Xiaoyan, Gao, Bo, Li, Kui, Wimmers, Klaus, Song, Chengyi

“…Molecular markers based on retrotransposon insertion polymorphisms (RIPs) have been developed and are widely used in plants and animals. Short interspersed…”
Get full text

Genetics of body fat mass and related traits in a pig population selected for leanness by Reyer, Henry, Varley, Patrick F., Murani, Eduard, Ponsuksili, Siriluck, Wimmers, Klaus

“…Obesity is characterized as the excessive accumulation of body fat and has a complex genetic foundation in humans including monogenic high-risk mutations and…”
Get full text

Lowered dietary phosphorus affects intestinal and renal gene expression to maintain mineral homeostasis with immunomodulatory implications in weaned piglets by Just, Franziska, Oster, Michael, Büsing, Kirsten, Borgelt, Luisa, Murani, Eduard, Ponsuksili, Siriluck, Wolf, Petra, Wimmers, Klaus

“…In monogastric animals, phosphorus (P) homeostasis is maintained by regulating intestinal absorption, bone mobilization, and renal excretion. Since P is a…”
Get full text

Correlated mRNAs and miRNAs from co-expression and regulatory networks affect porcine muscle and finally meat properties by Ponsuksili, Siriluck, Du, Yang, Hadlich, Frieder, Siengdee, Puntita, Murani, Eduard, Schwerin, Manfred, Wimmers, Klaus

“…Physiological processes aiding the conversion of muscle to meat involve many genes associated with muscle structure and metabolic processes. MicroRNAs regulate…”
Get full text

Identification of common regulators of genes in co-expression networks affecting muscle and meat properties by Ponsuksili, Siriluck, Siengdee, Puntita, Du, Yang, Trakooljul, Nares, Murani, Eduard, Schwerin, Manfred, Wimmers, Klaus

“…Understanding the genetic contributions behind skeletal muscle composition and metabolism is of great interest in medicine and agriculture. Attempts to dissect…”
Get full text

Gene expression and DNA-methylation of bovine pretransfer endometrium depending on its receptivity after in vitro-produced embryo transfer by Ponsuksili, Siriluck, Murani, Eduard, Schwerin, Manfred, Schellander, Karl, Tesfaye, Dawit, Wimmers, Klaus

“…Embryonic implantation to establish a pregnancy is a complex process that requires appropriate communication between the embryo and the maternal endometrium…”
Get full text

Prenatal Skeletal Muscle Transcriptome Analysis Reveals Novel MicroRNA-mRNA Networks Associated with Intrauterine Growth Restriction in Pigs by Ali, Asghar, Murani, Eduard, Hadlich, Frieder, Liu, Xuan, Wimmers, Klaus, Ponsuksili, Siriluck

“…Intrauterine growth restriction (IUGR) occurs in 15-20% of pig neonates and poses huge economic losses to the pig industry. IUGR piglets have reduced skeletal…”
Get full text

A substitution in the ligand binding domain of the porcine glucocorticoid receptor affects activity of the adrenal gland by Murani, Eduard, Reyer, Henry, Ponsuksili, Siriluck, Fritschka, Stephan, Wimmers, Klaus

“…Glucocorticoids produced in the adrenal cortex under the control of the hypothalamic-pituitary axis play a vital role in the maintenance of basal and…”
Get full text