Search Results - "Muramatsu, Shuji"

Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3H)‑ones and in Vivo Studies on a Surgically Induced Rat Model of Osteoarthritis by Atobe, Masakazu, Nagami, Takamichi, Muramatsu, Shuji, Ohno, Takeshi, Kitagawa, Masayuki, Suzuki, Hiroko, Ishiguro, Masashi, Watanabe, Atsushi, Kawanishi, Masashi

“…Osteoarthritis (OA) is a degenerative disease characterized by joint destruction and loss of cartilage. There are many unmet needs in the treatment of OA and…”
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Functional Gene Screening System Identified TRPV4 as a Regulator of Chondrogenic Differentiation by Muramatsu, Shuji, Wakabayashi, Makoto, Ohno, Takeshi, Amano, Katsuhiko, Ooishi, Rika, Sugahara, Toshinori, Shiojiri, Satoshi, Tashiro, Kosuke, Suzuki, Yutaka, Nishimura, Riko, Kuhara, Satoru, Sugano, Sumio, Yoneda, Toshiyuki, Matsuda, Akio

“…Sox9 is a transcription factor that is essential for chondrocyte differentiation and chondrocyte-specific gene expression. However, the precise mechanism of…”
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Production of recombinant extracellular cholesterol esterase using consistently active promoters in Burkholderia stabilis by Yoshida, Keitaro, Konishi, Kenji, Magana-Mora, Arturo, Rougny, Adrien, Yasutake, Yoshiaki, Muramatsu, Shuji, Murata, Satomi, Kumagai, Toshitaka, Aburatani, Sachiyo, Sakasegawa, Shin-ichi, Tamura, Tomohiro

“…Burkholderia stabilis FERMP-21014 produces highly active cholesterol esterase in the presence of fatty acids. To develop an overexpression system for…”
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Large-scale identification and characterization of human genes that activate NF-κB and MAPK signaling pathways by MATSUDA, Akio, SUZUKI, Yutaka, HAYASHI, Hiroshi, SUGANO, Sumio, HONDA, Goichi, MURAMATSU, Shuji, MATSUZAKI, Osamu, NAGANO, Yukiko, DOI, Takahiro, SHIMOTOHNO, Kunitada, HARADA, Takeshi, NISHIDA, Eisuke

“…We have carried out a large-scale identification and characterization of human genes that activate the NF-κB and MARK signaling pathways. We constructed…”
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Centaurin-α1 Is a Phosphatidylinositol 3-Kinase-dependent Activator of ERK1/2 Mitogen-activated Protein Kinases by Hayashi, Hideko, Matsuzaki, Osamu, Muramatsu, Shuji, Tsuchiya, Yoshiki, Harada, Takeshi, Suzuki, Yutaka, Sugano, Sumio, Matsuda, Akio, Nishida, Eisuke

“…Centaurin-α1 is known to be a phosphatidylinositol 3,4,5-triphosphate (PIP3)-binding protein that has two pleckstrin homology domains and a putative ADP…”
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An Escherichia coli protein that preferentially binds to sharply curved DNA by Yamada, H, Muramatsu, S, Mizuno, T

“…We attempted to find Escherichia coli proteins which preferentially bind to a curved DNA sequence even in the presence of an excess amount of a non-curved DNA…”
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Disruption of SMC-related genes promotes recombinant cholesterol esterase production in Burkholderia stabilis by Konishi, Kenji, Yasutake, Yoshiaki, Muramatsu, Shuji, Murata, Satomi, Yoshida, Keitaro, Ishiya, Koji, Aburatani, Sachiyo, Sakasegawa, Shin-ichi, Tamura, Tomohiro

“…Burkholderia stabilis strain FERMP-21014 secretes cholesterol esterase (BsChe), which is used in clinical settings to determine serum cholesterol levels…”
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Bacterial triacylglycerol lipase is a potential cholesterol esterase: Identification of a key determinant for sterol-binding specificity by Yasutake, Yoshiaki, Konishi, Kenji, Muramatsu, Shuji, Yoshida, Keitaro, Aburatani, Sachiyo, Sakasegawa, Shin-ichi, Tamura, Tomohiro

“…Cholesterol esterase (Che) from Burkholderia stabilis (BsChe) is a homolog of well-characterized and industrially relevant bacterial triacylglycerol lipases…”
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transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9 by Takigawa, Yoko, Hata, Kenji, Muramatsu, Shuji, Amano, Katsuhiko, Ono, Koichiro, Wakabayashi, Makoto, Matsuda, Akio, Takada, Kenji, Nishimura, Riko, Yoneda, Toshiyuki

“…Sox9 is an essential transcription factor for chondrogenesis by regulating the expression of chondrogenic genes. However, its regulatory mechanism is not fully…”
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Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription by Amano, Katsuhiko, Hata, Kenji, Muramatsu, Shuji, Wakabayashi, Makoto, Takigawa, Yoko, Ono, Koichiro, Nakanishi, Masako, Takashima, Rikako, Kogo, Mikihiko, Matsuda, Akio, Nishimura, Riko, Yoneda, Toshiyuki

“…SRY-box-containing gene 9 (Sox9) is an essential transcription factor in chondrocyte lineage determination and differentiation. Recent studies demonstrated…”
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Paraspeckle protein p54nrb links Sox9-mediated transcription with RNA processing during chondrogenesis in mice by Hata, Kenji, Nishimura, Riko, Muramatsu, Shuji, Matsuda, Akio, Matsubara, Takuma, Amano, Katsuhiko, Ikeda, Fumiyo, Harley, Vincent R, Yoneda, Toshiyuki

“…The Sox9 transcription factor plays an essential role in promoting chondrogenesis and regulating expression of chondrocyte extracellular-matrix genes. To…”
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Paraspeckle protein p54^sup nrb^ links Sox9-mediated transcription with RNA processing during chondrogenesis in mice by Hata, Kenji, Nishimura, Riko, Muramatsu, Shuji, Matsuda, Akio, Matsubara, Takuma, Amano, Katsuhiko, Ikeda, Fumiyo, Harley, Vincent R, Yoneda, Toshiyuki

“…The Sox9 transcription factor plays an essential role in promoting chondrogenesis and regulating expression of chondrocyte extracellular-matrix genes. To…”
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Paraspeckle protein [p54.sup.nrb] links Sox9-mediated transcription with RNA processing during chondrogenesis in mice by Hata, Kenji, Nishimura, Riko, Muramatsu, Shuji, Matsuda, Akio, Matsubara, Takuma, Amano, Katsuhiko, Ikeda, Fumiyo, Harley, Vincent R, Yoneda, Toshiyuki

“…The Sox9 transcription factor plays an essential role in promoting chondrogenesis and regulating expression of chondrocyte extracellular-matrix genes. To…”
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Centaurin-α1 Is a Phosphatidylinositol 3-Kinase-dependent Activator of ERK1/2 Mitogen-activated Protein Kinases by Hideko Hayashi, Osamu Matsuzaki, Shuji Muramatsu, Yoshiki Tsuchiya, Takeshi Harada, Yutaka Suzuki, Sumio Sugano, Akio Matsuda, Eisuke Nishida

“…Centaurin-α 1 is known to be a phosphatidylinositol 3,4,5-triphosphate (PIP 3 )-binding protein that has two pleckstrin homology domains and a putative ADP…”
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Centaurin-alpha1 is a phosphatidylinositol 3-kinase-dependent activator of ERK1/2 mitogen-activated protein kinases by Hayashi, Hideko, Matsuzaki, Osamu, Muramatsu, Shuji, Tsuchiya, Yoshiki, Harada, Takeshi, Suzuki, Yutaka, Sugano, Sumio, Matsuda, Akio, Nishida, Eisuke

“…Centaurin-alpha1 is known to be a phosphatidylinositol 3,4,5-triphosphate (PIP3)-binding protein that has two pleckstrin homology domains and a putative ADP…”
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Large-scale identification and characterization of human genes that activate NF- B and MAPK signaling pathways by Matsuda, Akio, Suzuki, Yutaka, Honda, Goichi, Muramatsu, Shuji, Matsuzaki, Osamu, Nagano, Yukiko, Doi, Takahiro, Shimotohno, Kunitada, Harada, Takeshi, Nishida, Eisuke, Hayashi, Hiroshi, Sugano, Sumio

“…We have carried out a large-scale identification and characterization of human genes that activate the NF-kappaB and MARK signaling pathways. We constructed…”
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Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways by Matsuda, Akio, Suzuki, Yutaka, Honda, Goichi, Muramatsu, Shuji, Matsuzaki, Osamu, Nagano, Yukiko, Doi, Takahiro, Shimotohno, Kunitada, Harada, Takeshi, Nishida, Eisuke, Hayashi, Hiroshi, Sugano, Sumio

“…We have carried out a large-scale identification and characterization of human genes that activate the NF-kappaB and MARK signaling pathways. We constructed…”
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Nucleotide sequence of the fabE gene and flanking regions containing a bent DNA sequence of Escherichia coli by MURAMATSU, S, MIZUNO, T

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Systematic characterization of curved DNA segments randomly cloned from Escherichia coli and their functional significance by Tanaka, K, Muramatsu, S, Yamada, H, Mizuno, T

“…In addition to the set of curved DNA segments isolated previously from Escherichia coli, another set of curved DNA segments has now been isolated. To gain an…”
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Insertion sequence IS5 contains a sharply curved DNA structure at its terminus by Muramatsu, S, Kato, M, Kohara, Y, Mizuno, T

“…It was demonstrated that insertion sequence IS5 contains a sequence-directed bent (sharply curved) DNA structure at its terminus, close to one of its 16 bp…”
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