Search Results - "Muralidharan, Mrinalini"
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Antibodies to watch in 2020
Published in mAbs (01-01-2020)“…This 2020 installment of the annual 'Antibodies to Watch' series documents the antibody therapeutics approved in 2019 and in regulatory review in the United…”
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Journal Article -
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A Mucosally Targeted Subunit Vaccine Candidate Eliciting HIV-1 Transcytosis-Blocking Abs
Published in Proceedings of the National Academy of Sciences - PNAS (14-09-2004)“…A vaccine that would engage the mucosal immune system against a broad range of HIV-1 subtypes and prevent epithelial transmission is highly desirable. Here we…”
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Journal Article -
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The Arabidopsis thaliana ortholog of a purported maize cholinesterase gene encodes a GDSL-lipase
Published in Plant molecular biology (01-04-2013)“…Acetylcholinesterase is an enzyme that is intimately associated with regulation of synaptic transmission in the cholinergic nervous system and in neuromuscular…”
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Plant-derived human acetylcholinesterase-R provides protection from lethal organophosphate poisoning and its chronic aftermath
Published in The FASEB journal (01-09-2007)“…Therapeutically valuable proteins are often rare and/or unstable in their natural context, calling for production solutions in heterologous systems. A relevant…”
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Journal Article -
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(32) Characterizing pea acetylcholinesterase
Published in Chemico-biological interactions (15-12-2005)“…Although the best-defined role of acetylcholinesterase (AChE) is to terminate cholinergic transmission signals, the presence of the enzyme and its substrate is…”
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Journal Article -
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Plant serine hydrolases and their function
Published 01-01-2009“…Acetylcholinesterase (AChE) is an enzyme that hydrolyses neurotransmitter acetylcholine in cholinergic synapse of all organisms with an organized nervous…”
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Dissertation -
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Altered gene expression in plants with constitutive expression of a mitochondrial small heat shock protein suggests the involvement of retrograde regulation in the heat stress response
Published in Physiologia plantarum (01-04-2005)“…Heat stress can negatively affect crop productivity. One way in which plants attempt to alleviate the effects of heat stress is to induce the expression of…”
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Journal Article -
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Purification of transgenic plant-derived recombinant human acetylcholinesterase-R
Published in Chemico-biological interactions (15-12-2005)“…Nicotiana benthamiana plants were engineered to express a codon-optimized gene encoding the human acetylcholinesterase-R (AChE) isoform. The transgenic plants…”
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Plant serine hydrolases and their function
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Dissertation