Search Results - "Muralidhar, R."
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Surface topography of polylactic acid nanofibrous mats: influence on blood compatibility
Published in Journal of materials science. Materials in medicine (01-09-2018)“…Fabricating nanofibrous scaffolds with robust blood compatibility remains an unmet challenge for cardiovascular applications since anti-thrombogenic surface…”
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2
Discovery of a Clinical Stage Multi-Kinase Inhibitor Sodium (E)-2-{2-Methoxy-5-[(2′,4′,6′-trimethoxystyrylsulfonyl)methyl]phenylamino}acetate (ON 01910.Na): Synthesis, Structure–Activity Relationship, and Biological Activity
Published in Journal of medicinal chemistry (22-09-2011)“…Cyclin D proteins are elevated in many cancer cells, and targeted deletion of cyclin D1 gene in the mammary tissues protects mice from breast cancer…”
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3
Sensitivity and specificity of teachers for vision screening among primary school children in South India
Published in Oman journal of ophthalmology (01-05-2019)“…AIMS: This study aims to determine the sensitivity and specificity of vision screening by school teachers among primary school children. SETTINGS AND DESIGN:…”
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4
Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors
Published in Bioorganic & medicinal chemistry (01-04-2008)“…A new series of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines were synthesized and evaluated as inhibitors of cyclooxygenase-2 and…”
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5
Antibody expression kinetics in glycoengineered Pichia pastoris
Published in Biotechnology and bioengineering (15-08-2010)“…Growth of the antibody market has fueled the development of alternative expression systems such as glycoengineered yeast. Although intact antibody expression…”
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6
Recurrent spontaneous coronary artery dissection: First case report in men with three episodes of spontaneous coronary dissection in separate vascular territories
Published in Catheterization and cardiovascular interventions (01-04-2016)“…Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome. In the literature, more than 1,200 cases of SCAD have been reported,…”
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Discovery of 8‑Cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3‑d]pyrimidine-6-carbonitrile (7x) as a Potent Inhibitor of Cyclin-Dependent Kinase 4 (CDK4) and AMPK-Related Kinase 5 (ARK5)
Published in Journal of medicinal chemistry (13-02-2014)“…The success of imatinib, a BCR-ABL inhibitor for the treatment of chronic myelogenous leukemia, has created a great impetus for the development of additional…”
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8
Visual outcome and incidence of glaucoma in patients with microspherophakia
Published in Eye (London) (01-03-2015)“…Introduction A number of ocular complications have been reported in microspherophakia. The literature however is limited to small case reports and the…”
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9
Refractory status epilepticus in a patient with SARS-CoV2 infection: Possible mechanisms
Published in Annals of the Indian Academy of Neurology (01-03-2022)Get full text
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10
Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2)
Published in Bioorganic & medicinal chemistry (15-02-2016)“…[Display omitted] Several families of protein kinases have been shown to play a critical role in the regulation of cell cycle progression, particularly…”
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11
Resistive Memory Process Optimization for High Resistance Switching Toward Scalable Analog Compute Technology for Deep Learning
Published in IEEE electron device letters (01-05-2021)“…We demonstrate a novel process for building a Resistive RAM (ReRAM) stack which reduces the forming voltage (<inline-formula> <tex-math…”
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12
Safety and efficacy of radial versus femoral access for rotational Atherectomy: A systematic review and meta-analysis
Published in Cardiovascular revascularization medicine (01-03-2019)“…Over the recent years, there has been increased interest in the use of transradial (TR) access for percutaneous coronary intervention (PCI), including…”
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13
Microbial keratitis after LASIK
Published in Journal of refractive surgery (1995) (01-03-2010)“…To report cases of microbial keratitis after LASIK from a tropical climatic zone. This retrospective case series included 17 eyes of 15 patients managed at our…”
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14
A response surface approach for the comparison of lipase production by Candida cylindracea using two different carbon sources
Published in Biochemical engineering journal (01-11-2001)“…A response surface approach has been used to study the production of extracellular lipase by Candida cylindracea. Medium constituents were optimised for the…”
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15
Glycoengineered Pichia produced anti-HER2 is comparable to trastuzumab in preclinical study
Published in mAbs (01-05-2011)“…Mammalian cell culture systems are used predominantly for the production of therapeutic monoclonal antibody (mAb) products. A number of alternative platforms,…”
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16
Outcome of delayed adjustable strabismus surgery in children using a bow-tie optional adjustable technique
Published in Indian journal of ophthalmology (01-02-2019)“…Purpose: The aim of this article is to study the feasibility of a delayed adjustable technique of strabismus surgery in children using an optional adjustable…”
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17
Oral epithelial cells transplanted on to corneal surface tend to adapt to the ocular phenotype
Published in Indian journal of ophthalmology (01-05-2014)“…To understand the response of oral epithelial cells, transplanted on corneal surface to the ocular cues in vivo. The corneal button obtained after penetrating…”
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18
A preliminary study on the treatment of amblyopia with Haidinger's brushes
Published in Journal of Clinical Ophthalmology and Research (01-01-2020)“…Introduction: A number of treatment options for amblyopia have been reported in the recent years. Haidinger's brushes have also been used to treat amblyopia…”
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(Z)-1-Aryl-3-arylamino-2-propen-1-ones, Highly Active Stimulators of Tubulin Polymerization: Synthesis, Structure–Activity Relationship (SAR), Tubulin Polymerization, and Cell Growth Inhibition Studies
Published in Journal of medicinal chemistry (14-06-2012)“…Tubulin, the major structural component of microtubules, is a target for the development of anticancer agents. A series of…”
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20
Improved production of monoclonal antibodies through oxygen-limited cultivation of glycoengineered yeast
Published in Journal of biotechnology (10-09-2011)“…Glycoengineering technology can elucidate and exploit glycan related structure–function relationships for therapeutic proteins. Glycoengineered yeast has been…”
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