Hypercalcemia with renal failure

We report a cse of nephrocalcinosis with renal failure which on evaluation was found to have hypercalcemia. Further investigations showed an inappropriately normal intact parathormone (iPTH) and 1,25 dihydroxy-vitamin D level in the setting of renal failure. Probing for a cause of non-PTH mediated h...

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Bibliographic Details
Published in:	Journal of the Association of Physicians of India Vol. 60; pp. 52 - 54
Main Authors:	Bhavani, Nisha, Praveen, Valiyaparambil Pavithran, Jayakumar, Rohinivilasam Vasukutty, Nair, Vasantha, Muraleedharan, Mangath, Kuma, Harish, Unnikrishnan, Ambika Gopalakrishnan, Menon, Vadayath Usha
Format:	Journal Article
Language:	English
Published:	India 01-06-2012
Subjects:	Acute Kidney Injury - etiology Glucocorticoids - therapeutic use Humans Hypercalcemia - etiology Hyperphosphatemia - etiology Male Middle Aged Nephrocalcinosis - etiology Parathyroid Hormone - blood Prednisolone - therapeutic use Sarcoidosis - complications Sarcoidosis - diagnosis Sarcoidosis - drug therapy Splenomegaly - etiology
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Summary:	We report a cse of nephrocalcinosis with renal failure which on evaluation was found to have hypercalcemia. Further investigations showed an inappropriately normal intact parathormone (iPTH) and 1,25 dihydroxy-vitamin D level in the setting of renal failure. Probing for a cause of non-PTH mediated hypercalcemia led to the diagnosis of sarcoidosis. Treatment with glucocorticoids could partially reverse the renal failure and control the hypercalcemia. This case illustrates the importance of careful interpretation of laboratory parameters especially levels of iPTH and vitamin D metabolites in renal failure.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0004-5772