Search Results - "Murai, Akiho"
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Rewriting the Central Dogma with Synthetic Genetic Polymers
Published in Chemical & pharmaceutical bulletin (01-05-2022)“…DNA and RNA are ubiquitous molecules responsible for storage and transmission of genetic information and together comprise the central dogma of molecular…”
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Cas9-mediated DNA cleavage guided by enzymatically prepared 4'-thio-modified RNA
Published in Organic & biomolecular chemistry (06-07-2022)“…CRISPR-Cas9-mediated DNA editing relies on guide RNAs (gRNAs) that direct site-specific DNA cleavage by the Cas endonuclease. Because natural gRNA is…”
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5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2
Published in iScience (22-10-2021)“…Newly emerging or re-emerging viral infections continue to cause significant morbidity and mortality every year worldwide, resulting in serious effects on both…”
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Journal Article