Search Results - "Mur, Emilie Bousquet"
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Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma
Published in The Journal of clinical investigation (01-02-2020)“…EGFR-mutated lung adenocarcinoma patients treated with gefitinib and osimertinib show a therapeutic benefit limited by the appearance of secondary mutations,…”
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Journal Article -
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MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis
Published in Scientific reports (11-03-2021)“…Alterations to cell polarization or to intercellular junctions are often associated with epithelial cancer progression, including breast cancers (BCa). We show…”
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Journal Article -
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c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling
Published in Cancer cell (12-02-2018)“…A quarter of all solid tumors harbor KRAS oncogenes. Yet, no selective drugs have been approved to treat these malignancies. Genetic interrogation of the MAPK…”
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Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF
Published in Cancer cell (15-04-2019)“…Five-year survival for pancreatic ductal adenocarcinoma (PDAC) patients remains below 7% due to the lack of effective treatments. Here, we report that combined…”
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Journal Article