Search Results - "Muok, Erick M O"
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SCHISTOACT: a protocol for an open-label, five-arm, non-inferiority, individually randomized controlled trial of the efficacy and safety of praziquantel plus artemisinin-based combinations in the treatment of Schistosoma mansoni infection
Published in Current controlled trials in cardiovascular medicine (27-11-2023)“…Abstract Background Schistosomiasis control relies on praziquantel for preventive chemotherapy. Alternative drugs are needed for the treatment and control of…”
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Efficacy and safety of single-dose artesunate plus sulfalene/pyrimethamine combined with praziquantel for the treatment of children with Schistosoma mansoni or Schistosoma haematobium in western Kenya: a randomised, open-label controlled trial
Published in Parasites & vectors (28-06-2024)“…Reliance on praziquantel for the treatment and control of schistosomiasis is likely to facilitate the emergence of drug resistance. Combination therapy…”
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ALIMUS-We are feeding! Study protocol of a multi-center, cluster-randomized controlled trial on the effects of a home garden and nutrition counseling intervention to reduce child undernutrition in rural Burkina Faso and Kenya
Published in Current controlled trials in cardiovascular medicine (01-06-2022)“…Climate change heavily affects child nutritional status in sub-Saharan Africa. Agricultural and dietary diversification are promising tools to balance…”
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Correction: ALIMUS-We are feeding! Study protocol of a multi-center, cluster-randomized controlled trial on the effects of a home garden and nutrition counseling intervention to reduce child undernutrition in rural Burkina Faso and Kenya
Published in Current controlled trials in cardiovascular medicine (13-06-2022)Get full text
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Aberrant plasma MMP and TIMP dynamics in Schistosoma - Immune reconstitution inflammatory syndrome (IRIS)
Published in PLoS neglected tropical diseases (01-08-2018)“…Among the different faces of immune reconstitution inflammatory syndrome (IRIS) developing in HIV-patients, no clinical definition has been reported for…”
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Sex-differential non-specific effects of adjuvanted and non-adjuvanted rabies vaccines versus placebo on all-cause mortality in dogs (NERVE-Dog study): a study protocol for a randomized controlled trial with a nested case-control study
Published in BMC veterinary research (01-10-2022)“…It has been proposed that childhood vaccines in high-mortality populations may have substantial impacts on mortality rates that are not explained by the…”
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Efficacy of artesunate with sulfalene plus pyrimethamine versus praziquantel for treatment of Schistosoma mansoni in Kenyan children: an open-label randomised controlled trial
Published in The Lancet infectious diseases (01-09-2010)“…Summary Background Schistosomiasis is an important parasitic disease in Kenya. Decreasing susceptibility of schistosomes to praziquantel, the major drug used…”
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Increases in Levels of Schistosome-Specific Immunoglobulin E and CD23+ B Cells in a Cohort of Kenyan Children Undergoing Repeated Treatment and Reinfection with Schistosoma mansoni
Published in The Journal of infectious diseases (15-08-2010)“…Background. Age prevalence curves for areas in which schistosomiasis is endemic suggest that humans develop partial immunity to reinfection beginning in early…”
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Influence of exposure history on the immunology and development of resistance to human Schistosomiasis mansoni
Published in PLoS neglected tropical diseases (01-03-2010)“…Previous studies suggest that humans can acquire immunity to reinfection with schistosomes, most probably due to immunologic mechanisms acquired after exposure…”
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Impact of Mothers' Schistosomiasis Status During Gestation on Children's IgG Antibody Responses to Routine Vaccines 2 Years Later and Anti-Schistosome and Anti-Malarial Responses by Neonates in Western Kenya
Published in Frontiers in immunology (18-06-2018)“…The potential consequences of parasitic infections on a person's immune responsiveness to unrelated antigens are often conjectured upon in relationship to…”
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T regulatory cell levels decrease in people infected with Schistosoma mansoni on effective treatment
Published in The American journal of tropical medicine and hygiene (01-10-2007)“…Schistosomiasis mansoni is usually a chronic infection that leads to long-term, systemic exposure to schistosome antigens. Experimental Schistosoma mansoni…”
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'Counselling is not just providing information': perceptions of caregivers and stakeholders on the design of nutrition and health counselling interventions for families with young children in rural Kenya
Published in BMC health services research (07-05-2024)“…Globally, a fifth of the children continue to face chronic undernutrition with a majority of them situated in the Low- and Middle-Income Countries (LMIC). The…”
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Association between CD4+ T-lymphocyte counts and fecal excretion of Schistosoma mansoni eggs in patients coinfected with S. mansoni and human immunodeficiency virus before and after initiation of antiretroviral therapy
Published in The American journal of tropical medicine and hygiene (10-07-2013)“…Previously, we have shown that persons with human immunodeficiency virus 1 (HIV-1) infection and reduced CD4(+) T-lymphocyte counts excrete significantly fewer…”
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Short Report : Childhood Coinfections with Plasmodium falciparum and Schistosoma mansoni Result in Lower Percentages of Activated T Cells and T Regulatory Memory Cells than Schistosomiasis Only
Published in The American journal of tropical medicine and hygiene (01-03-2009)“…Flow cytometric analyses were performed to evaluate HLA-DR (+) activated T lymphocytes (Tact; CD3 (+)/CD4 (+)/CD25(medium)) and T regulatory cells (Treg; CD3…”
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Sustainable home gardens in Western Kenya: A qualitative study for co-designing nutrition-sensitive interventions
Published in Journal of rural studies (01-10-2023)“…Populations living in rural sub-Saharan Africa (SSA) increasingly face negative climate change impacts on their nutrition and health status. For smallholder…”
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Short Report: Association Between CD4 super(+) T-Lymphocyte Counts and Fecal Excretion of Schistosoma mansoni Eggs in Patients Coinfected with S. mansoni and Human Immunodeficiency Virus Before and After Initiation of Antiretroviral Therapy
Published in The American journal of tropical medicine and hygiene (01-07-2013)“…Previously, we have shown that persons with human immunodeficiency virus 1 (HIV-1) infection and reduced CD4 super(+) T-lymphocyte counts excrete significantly…”
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