Search Results - "Munz, Clara M"

Fate mapping of hematopoietic stem cells reveals two pathways of native thrombopoiesis by Morcos, Mina N. F., Li, Congxin, Munz, Clara M., Greco, Alessandro, Dressel, Nicole, Reinhardt, Susanne, Sameith, Katrin, Dahl, Andreas, Becker, Nils B., Roers, Axel, Höfer, Thomas, Gerbaulet, Alexander

“…Hematopoietic stem cells (HSCs) produce highly diverse cell lineages. Here, we chart native lineage pathways emanating from HSCs and define their physiological…”
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Regeneration after blood loss and acute inflammation proceeds without contribution of primitive HSCs by Munz, Clara M., Dressel, Nicole, Chen, Minyi, Grinenko, Tatyana, Roers, Axel, Gerbaulet, Alexander

“…•Cumulative recording of proliferation and differentiation in situ shows that primitive HSCs are not activated by inflammation or blood loss. [Display omitted]…”
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Activation of the cGAS/STING axis in genome-damaged hematopoietic cells does not impact blood cell formation or leukemogenesis by Dressel, Nicole, Natusch, Loreen, Munz, Clara M, Costas Ramon, Santiago, Morcos, Mina N F, Loff, Anja, Hiller, Björn, Haase, Christa, Schulze, Livia, Müller, Patrick, Lesche, Mathias, Dahl, Andreas, Luksch, Hella, Roesen-Wolff, Angela, Roers, Axel, Behrendt, Rayk, Gerbaulet, Alexander

“…Genome damage is a main driver of malignant transformation, but it also induces aberrant inflammation via the cGAS/STING DNA sensing pathway. Activation of…”
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Visualization of individual cell division history in complex tissues using iCOUNT by Denoth-Lippuner, Annina, Jaeger, Baptiste N., Liang, Tong, Royall, Lars N., Chie, Stefanie E., Buthey, Kilian, Machado, Diana, Korobeynyk, Vladislav I., Kruse, Merit, Munz, Clara M., Gerbaulet, Alexander, Simons, Benjamin D., Jessberger, Sebastian

“…The division potential of individual stem cells and the molecular consequences of successive rounds of proliferation remain largely unknown. Here, we developed…”
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Continuous mitotic activity of primitive hematopoietic stem cells in adult mice by Morcos, Mina N F, Zerjatke, Thomas, Glauche, Ingmar, Munz, Clara M, Ge, Yan, Petzold, Andreas, Reinhardt, Susanne, Dahl, Andreas, Anstee, Natasha S, Bogeska, Ruzhica, Milsom, Michael D, Säwén, Petter, Wan, Haixia, Bryder, David, Roers, Axel, Gerbaulet, Alexander

“…The proliferative activity of aging hematopoietic stem cells (HSCs) is controversially discussed. Inducible fluorescent histone 2B fusion protein (H2B-FP)…”
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