Search Results - "Munusamy Ponnan, Sivasankaran"

Evaluation of antiviral T cell responses and TSCM cells in volunteers enrolled in a phase I HIV-1 subtype C prophylactic vaccine trial in India by Munusamy Ponnan, Sivasankaran, Hayes, Peter, Fernandez, Natalia, Thiruvengadam, Kannan, Pattabiram, Sathyamurthi, Nesakumar, Manohar, Srinivasan, Ashokkumar, Kathirvel, Sujitha, Shankar, Janani, Goyal, Rajat, Singla, Nikhil, Mukherjee, Joyeeta, Chatrath, Shweta, Gilmour, Jill, Subramanyam, Sudha, Prasad Tripathy, Srikanth, Swaminathan, Soumya, Hanna, Luke Elizabeth

“…T cells play an important role in controlling viral replication during HIV infection. An effective vaccine should, therefore, lead to the induction of a strong…”
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Induction of circulating T follicular helper cells and regulatory T cells correlating with HIV-1 gp120 variable loop antibodies by a subtype C prophylactic vaccine tested in a Phase I trial in India by Munusamy Ponnan, Sivasankaran, Swaminathan, Soumya, Tiruvengadam, Kannan, K K, Vidyavijayan, Cheedarla, Narayana, Nesakumar, Manohar, Kathirvel, Sujitha, Goyal, Rajat, Singla, Nikhil, Mukherjee, Joyeeta, Bergin, Philip, T Kopycinski, Jakub, Gilmour, Jill, Prasad Tripathy, Srikanth, Luke, Hanna Elizabeth

“…A Phase I HIV-1 vaccine trial sponsored by the International AIDS Vaccine Initiative (IAVI) was conducted in India in 2009 to test a subtype C prophylactic…”
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Induction and maintenance of bi-functional (IFN-γ + IL-2+ and IL-2+ TNF-α+) T cell responses by DNA prime MVA boosted subtype C prophylactic vaccine tested in a Phase I trial in India by Munusamy Ponnan, Sivasankaran, Pattabiram, Sathyamurthy, Thiruvengadam, Kannan, Goyal, Rajat, Singla, Nikhil, Mukherjee, Joyeeta, Chatrath, Shweta, Bergin, Philip, T Kopycinski, Jakub, Gilmour, Jill, Kumar, Sriram, Muthu, Malathy, Subramaniam, Sudha, Swaminathan, Soumya, Prasad Tripathy, Srikanth, Luke, Hanna Elizabeth

“…Effective vaccine design relies on accurate knowledge of protection against a pathogen, so as to be able to induce relevant and effective protective responses…”
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Multi-omics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity by Ambikan, Anoop T, Yang, Hong, Krishnan, Shuba, Svensson Akusjärvi, Sara, Gupta, Soham, Lourda, Magda, Sperk, Maike, Arif, Muhammad, Zhang, Cheng, Nordqvist, Hampus, Ponnan, Sivasankaran Munusamy, Sönnerborg, Anders, Treutiger, Carl Johan, O'Mahony, Liam, Mardinoglu, Adil, Benfeitas, Rui, Neogi, Ujjwal

“…The clinical outcome and disease severity in coronavirus disease 2019 (COVID-19) are heterogeneous, and the progression or fatality of the disease cannot be…”
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Role of Circulating T Follicular Helper Cells and Stem-Like Memory CD4 + T Cells in the Pathogenesis of HIV-2 Infection and Disease Progression by Ponnan, Sivasankaran Munusamy, Vidyavijayan, K K, Thiruvengadam, Kannan, Hilda J, Nancy, Mathayan, Manikannan, Murugavel, Kailapuri Gangatharan, Hanna, Luke Elizabeth

“…CD4 T cells are critical players in the host adaptive immune response. Emerging evidence suggests that certain CD4 T cell subsets contribute significantly to…”
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Elevated Numbers of HIV-Specific Poly-Functional CD8 + T Cells With Stem Cell-Like and Follicular Homing Phenotypes in HIV-Exposed Seronegative Individuals by Munusamy Ponnan, Sivasankaran, Thiruvengadam, Kannan, Kathirvel, Sujitha, Shankar, Janani, Rajaraman, Akshaya, Mathaiyan, Manikannan, Dinesha, Thongadi Ramesh, Poongulali, Selvamuthu, Saravanan, Shanmugam, Murugavel, Kailapuri Gangatharan, Swaminathan, Soumya, Tripathy, Srikanth Prasad, Neogi, Ujjwal, Velu, Vijayakumar, Hanna, Luke Elizabeth

“…HIV-specific CD8 T cells are known to play a key role in viral control during acute and chronic HIV infection. Although many studies have demonstrated the…”
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Association of circulatory Tfh-like cells with neutralizing antibody responses among chronic HIV-1 subtype C infected long-term nonprogressors and progressors by Swathirajan, Chinnambedu Ravichandran, Nandagopal, Pannerselvam, Vignesh, Ramachandran, Srikrishnan, Aylur Kailasam, Goyal, Rajat, Qureshi, Huma, Saravanan, Shanmugam, Solomon, Sunil Suhas, Hanna, Luke Elizabeth, Sivasankaran, Munusamy Ponnan, Singla, Nikhil, Mukherjee, Joyeeta, Chatrath, Shweta, Kopycinski, Jakub, Murugavel, Kailapuri Gangatharan

“…HIV-1 vaccine functioning relies on successful induction of broadly neutralizing antibodies (bNAbs). CXCR3- circulatory T-follicular helper (cTfh) cells are…”
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Distinct lipid profile, low-level inflammation, and increased antioxidant defense signature in HIV-1 elite control status by Sperk, Maike, Mikaeloff, Flora, Svensson-Akusjärvi, Sara, Krishnan, Shuba, Ponnan, Sivasankaran Munusamy, Ambikan, Anoop T., Nowak, Piotr, Sönnerborg, Anders, Neogi, Ujjwal

“…HIV-1 elite controllers (EC) are a rare but heterogeneous group of HIV-1-infected individuals who can suppress viral replication in the absence of…”
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Deciphering the Role of Mucosal Immune Responses and the Cervicovaginal Microbiome in Resistance to HIV Infection in HIV-Exposed Seronegative (HESN) Women by Munusamy Ponnan, Sivasankaran, Thiruvengadam, Kannan, Tellapragada, Chaitanya, Ambikan, Anoop T, Narayanan, Aswathy, Kathirvel, Sujitha, Mathayan, Manikannan, Shankar, Janani, Rajaraman, Akshaya, Afshan Amanulla, Mehar, Dinesha, Thongadi Ramesh, Poongulali, Selvamuthu, Saravanan, Shanmugam, Murugavel, Kailapuri Gangatharan, Swaminathan, Soumya, Velu, Vijayakumar, Shacklett, Barbara, Neogi, Ujjwal, Hanna, Luke Elizabeth

“…The female genital tract (FGT) is an important site of human immunodeficiency virus (HIV) infection. Discerning the nature of HIV-specific local immune…”
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Plasma CXCL8 and MCP-1 as surrogate plasma biomarkers of latent tuberculosis infection among household contacts-A cross-sectional study by Selvavinayagam, Sivaprakasam T, Aswathy, Bijulal, Yong, Yean K, Frederick, Asha, Murali, Lakshmi, Kalaivani, Vasudevan, Karishma, Sree J, Rajeshkumar, Manivannan, Anusree, Adukkadukkam, Kannan, Meganathan, Gopalan, Natarajan, Vignesh, Ramachandran, Murugesan, Amudhan, Tan, Hong Yien, Zhang, Ying, Chandramathi, Samudi, Sivasankaran, Munusamy Ponnan, Balakrishnan, Pachamuthu, Govindaraj, Sakthivel, Byrareddy, Siddappa N, Velu, Vijayakumar, Larsson, Marie, Shankar, Esaki M, Raju, Sivadoss

“…Early detection of latent tuberculosis infection (LTBI) is critical to TB elimination in the current WHO vision of End Tuberculosis Strategy. The study…”
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Metabolic Perturbation Associated With COVID-19 Disease Severity and SARS-CoV-2 Replication by Krishnan, Shuba, Nordqvist, Hampus, Ambikan, Anoop T., Gupta, Soham, Sperk, Maike, Svensson-Akusjärvi, Sara, Mikaeloff, Flora, Benfeitas, Rui, Saccon, Elisa, Ponnan, Sivasankaran Munusamy, Rodriguez, Jimmy Esneider, Nikouyan, Negin, Odeh, Amani, Ahlén, Gustaf, Asghar, Muhammad, Sällberg, Matti, Vesterbacka, Jan, Nowak, Piotr, Végvári, Ákos, Sönnerborg, Anders, Treutiger, Carl Johan, Neogi, Ujjwal

“…Viruses hijack host metabolic pathways for their replicative advantage. In this study, using patient-derived multiomics data and in vitro infection assays, we…”
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Role of myeloid cells in system-level immunometabolic dysregulation during prolonged successful HIV-1 treatment by Svensson Akusjärvi, Sara, Krishnan, Shuba, Ambikan, Anoop T., Mikaeloff, Flora, Munusamy Ponnan, Sivasankaran, Vesterbacka, Jan, Lourda, Magda, Nowak, Piotr, Sönnerborg, Anders, Neogi, Ujjwal

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Role of myeloid cells in system-level immunometabolic dysregulation during prolonged successful HIV-1 treatment by Svensson Akusjärvi, Sara, Krishnan, Shuba, Ambikan, Anoop T., Mikaeloff, Flora, Munusamy Ponnan, Sivasankaran, Vesterbacka, Jan, Lourda, Magda, Nowak, Piotr, Sönnerborg, Anders, Neogi, Ujjwal

“…Why people with HIV-1 on ART (PWH ART ) display convoluted metabolism and immune cell functions during prolonged suppressive therapy is not well evaluated. In…”
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Molecular characterization of Enterococcus faecalis isolates from urinary tract infection and interaction between Enterococcus faecalis encountered Dendritic and Natural Killer cells by Kathirvel, Sujitha, Mani, Maheswaran, Gopala Krishnan, Gopi Krishnan, Sethumadhavan, Aiswarya, Vijayalakshmi, T., Ponnan, Sivasankaran Munusamy, Hanna, Luke Elizabeth, Mathaiyan, Manikannan

“…Enterococcus faecalis is an emerging nosocomial pathogen. The study investigates the E. faecalis specific innate immune cells interplay between Natural Killer…”
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Induction and maintenance of bi-functional by Munusamy Ponnan, Sivasankaran, Pattabiram, Sathyamurthy, Thiruvengadam, Kannan, Goyal, Rajat, Singla, Nikhil, Mukherjee, Joyeeta, Chatrath, Shweta, Bergin, Philip, T. Kopycinski, Jakub, Gilmour, Jill, Kumar, Sriram, Muthu, Malathy, Subramaniam, Sudha, Swaminathan, Soumya, Prasad Tripathy, Srikanth, Luke, Hanna Elizabeth

“…Effective vaccine design relies on accurate knowledge of protection against a pathogen, so as to be able to induce relevant and effective protective responses…”
Get full text

Evaluation of antiviral T cell responses and T.sub.SCM cells in volunteers enrolled in a phase I HIV-1 subtype C prophylactic vaccine trial in India by Munusamy Ponnan, Sivasankaran, Hayes, Peter, Fernandez, Natalia, Thiruvengadam, Kannan, Pattabiram, Sathyamurthi, Nesakumar, Manohar, Srinivasan, Ashokkumar, Kathirvel, Sujitha, Shankar, Janani, Goyal, Rajat, Singla, Nikhil, Mukherjee, Joyeeta, Chatrath, Shweta, Gilmour, Jill, Subramanyam, Sudha, Prasad Tripathy, Srikanth, Swaminathan, Soumya, Hanna, Luke Elizabeth, Ansari, Aftab A

“…T cells play an important role in controlling viral replication during HIV infection. An effective vaccine should, therefore, lead to the induction of a strong…”
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Plasma CXCL8 and MCP-1 as surrogate plasma biomarkers of latent tuberculosis infection among household contacts–A cross-sectional study by Sivaprakasam T. Selvavinayagam, Bijulal Aswathy, Yean K. Yong, Asha Frederick, Lakshmi Murali, Vasudevan Kalaivani, Sree J. Karishma, Manivannan Rajeshkumar, Adukkadukkam Anusree, Meganathan Kannan, Natarajan Gopalan, Ramachandran Vignesh, Amudhan Murugesan, Hong Yien Tan, Ying Zhang, Samudi Chandramathi, Munusamy Ponnan Sivasankaran, Pachamuthu Balakrishnan, Sakthivel Govindaraj, Siddappa N. Byrareddy, Vijayakumar Velu, Marie Larsson, Esaki M. Shankar, Sivadoss Raju

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