Search Results - "Muntel, Jan"

MassIVE.quant: a community resource of quantitative mass spectrometry–based proteomics datasets by Choi, Meena, Carver, Jeremy, Chiva, Cristina, Tzouros, Manuel, Huang, Ting, Tsai, Tsung-Heng, Pullman, Benjamin, Bernhardt, Oliver M., Hüttenhain, Ruth, Teo, Guo Ci, Perez-Riverol, Yasset, Muntel, Jan, Müller, Maik, Goetze, Sandra, Pavlou, Maria, Verschueren, Erik, Wollscheid, Bernd, Nesvizhskii, Alexey I., Reiter, Lukas, Dunkley, Tom, Sabidó, Eduard, Bandeira, Nuno, Vitek, Olga

“…MassIVE.quant is a repository infrastructure and data resource for reproducible quantitative mass spectrometry–based proteomics, which is compatible with all…”
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Different syngeneic tumors show distinctive intrinsic tumor-immunity and mechanisms of actions (MOA) of anti-PD-1 treatment by Jin, Ying, An, Xiaoyu, Mao, Binchen, Sun, Ruilin, Kumari, Rajendra, Chen, Xiaobo, Shan, Yongli, Zang, Mingfa, Xu, Ling, Muntel, Jan, Beeler, Kristina, Bruderer, Roland, Reiter, Lukas, Guo, Sheng, Zhou, Demin, Li, Qi-Xiang, Ouyang, Xuesong

“…Cancers are immunologically heterogeneous. A range of immunotherapies target abnormal tumor immunity via different mechanisms of actions (MOAs), particularly…”
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Systematic Comparison of Strategies for the Enrichment of Lysosomes by Data Independent Acquisition by Singh, Jasjot, Kaade, Edgar, Muntel, Jan, Bruderer, Roland, Reiter, Lukas, Thelen, Melanie, Winter, Dominic

“…In mammalian cells, the lysosome is the main organelle for the degradation of macromolecules and the recycling of their building blocks. Correct lysosomal…”
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FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease by Mair, Waltraud, Muntel, Jan, Tepper, Katharina, Tang, Shaojun, Biernat, Jacek, Seeley, William W, Kosik, Kenneth S, Mandelkow, Eckhard, Steen, Hanno, Steen, Judith A

“…Tauopathies, including Alzheimer’s disease (AD), are associated with the aggregation of modified microtubule associated protein tau. This pathological state of…”
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Surpassing 10 000 identified and quantified proteins in a single run by optimizing current LC-MS instrumentation and data analysis strategy by Muntel, Jan, Gandhi, Tejas, Verbeke, Lynn, Bernhardt, Oliver M, Treiber, Tobias, Bruderer, Roland, Reiter, Lukas

“…Comprehensive proteome quantification is crucial for a better understanding of underlying mechanisms of diseases. Liquid chromatography mass spectrometry…”
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Quantitative prediction of genome-wide resource allocation in bacteria by Goelzer, Anne, Muntel, Jan, Chubukov, Victor, Jules, Matthieu, Prestel, Eric, Nölker, Rolf, Mariadassou, Mahendra, Aymerich, Stéphane, Hecker, Michael, Noirot, Philippe, Becher, Dörte, Fromion, Vincent

“…Predicting resource allocation between cell processes is the primary step towards decoding the evolutionary constraints governing bacterial growth under…”
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Comprehensive Absolute Quantification of the Cytosolic Proteome of Bacillus subtilis by Data Independent, Parallel Fragmentation in Liquid Chromatography/Mass Spectrometry (LC/MSE) by Muntel, Jan, Fromion, Vincent, Goelzer, Anne, Maaβ, Sandra, Mäder, Ulrike, Büttner, Knut, Hecker, Michael, Becher, Dörte

“…In the growing field of systems biology, the knowledge of protein concentrations is highly required to truly understand metabolic and adaptational networks…”
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Efficient, Global-Scale Quantification of Absolute Protein Amounts by Integration of Targeted Mass Spectrometry and Two-Dimensional Gel-Based Proteomics by Maass, Sandra, Sievers, Susanne, Zühlke, Daniela, Kuzinski, Judith, Sappa, Praveen K, Muntel, Jan, Hessling, Bernd, Bernhardt, Jörg, Sietmann, Rabea, Völker, Uwe, Hecker, Michael, Becher, Dörte

“…Knowledge on absolute protein concentrations is mandatory for the simulation of biological processes in the context of systems biology. A novel approach for…”
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Abundance-based Classifier for the Prediction of Mass Spectrometric Peptide Detectability Upon Enrichment (PPA)[S] by Muntel, Jan, Boswell, Sarah A., Tang, Shaojun, Ahmed, Saima, Wapinski, Ilan, Foley, Greg, Steen, Hanno, Springer, Michael

“…The function of a large percentage of proteins is modulated by post-translational modifications (PTMs). Currently, mass spectrometry (MS) is the only…”
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Stress responses of the industrial workhorse Bacillus licheniformis to osmotic challenges by Schroeter, Rebecca, Hoffmann, Tamara, Voigt, Birgit, Meyer, Hanna, Bleisteiner, Monika, Muntel, Jan, Jürgen, Britta, Albrecht, Dirk, Becher, Dörte, Lalk, Michael, Evers, Stefan, Bongaerts, Johannes, Maurer, Karl-Heinz, Putzer, Harald, Hecker, Michael, Schweder, Thomas, Bremer, Erhard

“…The Gram-positive endospore-forming bacterium Bacillus licheniformis can be found widely in nature and it is exploited in industrial processes for the…”
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FLEXIQuant-LF to quantify protein modification extent in label-free proteomics data by Schlaffner, Christoph N, Kahnert, Konstantin, Muntel, Jan, Chauhan, Ruchi, Renard, Bernhard Y, Steen, Judith A, Steen, Hanno

“…Improvements in LC-MS/MS methods and technology have enabled the identification of thousands of modified peptides in a single experiment. However, protein…”
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The dynamic protein partnership of RNA polymerase in Bacillus subtilis by Delumeau, Olivier, Lecointe, François, Muntel, Jan, Guillot, Alain, Guédon, Eric, Monnet, Véronique, Hecker, Michael, Becher, Dörte, Polard, Patrice, Noirot, Philippe

“…In prokaryotes, transcription results from the activity of a 400 kDa RNA polymerase (RNAP) protein complex composed of at least five subunits (2α, β, β', ω)…”
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The dynamic protein partnership of RNA polymerase inBacillus subtilis by Delumeau, Olivier, Lecointe, François, Muntel, Jan, Guillot, Alain, Guédon, Eric, Monnet, Véronique, Hecker, Michael, Becher, Dörte, Polard, Patrice, Noirot, Philippe

“…In prokaryotes, transcription results from the activity of a 400 kDa RNA polymerase (RNAP) protein complex composed of at least five subunits (2α, β, β′, ω)…”
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Comparison of Protein Quantification in a Complex Background by DIA and TMT Workflows with Fixed Instrument Time by Muntel, Jan, Kirkpatrick, Joanna, Bruderer, Roland, Huang, Ting, Vitek, Olga, Ori, Alessandro, Reiter, Lukas

“…Label-free quantification (LFQ) and isobaric labeling quantification (ILQ) are among the most popular protein quantification workflows in discovery proteomics…”
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Combining Precursor and Fragment Information for Improved Detection of Differential Abundance in Data Independent Acquisition by Huang, Ting, Bruderer, Roland, Muntel, Jan, Xuan, Yue, Vitek, Olga, Reiter, Lukas

“…DIA profiles of complex biological matrices such as tissues can contain quantitative interferences, and the interferences at the MS1 and the MS2 signals are…”
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Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer’s Disease by Wesseling, Hendrik, Mair, Waltraud, Kumar, Mukesh, Schlaffner, Christoph N., Tang, Shaojun, Beerepoot, Pieter, Fatou, Benoit, Guise, Amanda J., Cheng, Long, Takeda, Shuko, Muntel, Jan, Rotunno, Melissa S., Dujardin, Simon, Davies, Peter, Kosik, Kenneth S., Miller, Bruce L., Berretta, Sabina, Hedreen, John C., Grinberg, Lea T., Seeley, William W., Hyman, Bradley T., Steen, Hanno, Steen, Judith A.

“…To elucidate the role of Tau isoforms and post-translational modification (PTM) stoichiometry in Alzheimer’s disease (AD), we generated a high-resolution…”
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Advancing Urinary Protein Biomarker Discovery by Data-Independent Acquisition on a Quadrupole-Orbitrap Mass Spectrometer by Muntel, Jan, Xuan, Yue, Berger, Sebastian T, Reiter, Lukas, Bachur, Richard, Kentsis, Alex, Steen, Hanno

“…The promises of data-independent acquisition (DIA) strategies are a comprehensive and reproducible digital qualitative and quantitative record of the proteins…”
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Biomarker Candidates for Tumors Identified from Deep-Profiled Plasma Stem Predominantly from the Low Abundant Area by Tognetti, Marco, Sklodowski, Kamil, Müller, Sebastian, Kamber, Dominique, Muntel, Jan, Bruderer, Roland, Reiter, Lukas

“…The plasma proteome has the potential to enable a holistic analysis of the health state of an individual. However, plasma biomarker discovery is difficult due…”
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Analysis of 1508 Plasma Samples by Capillary-Flow Data-Independent Acquisition Profiles Proteomics of Weight Loss and Maintenance'[S] by Bruderer, Roland, Muntel, Jan, Müller, Sebastian, Bernhardt, Oliver M., Gandhi, Tejas, Cominetti, Ornella, Macron, Charlotte, Carayol, Jérôme, Rinner, Oliver, Astrup, Arne, Saris, Wim H.M., Hager, Jörg, Valsesia, Armand, Dayon, Loïc, Reiter, Lukas

“…We established a robust capillary-flow data-independent acquisition MS platform capable of measuring 31 plasma proteomes per day without the need of repeated…”
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MStern Blotting–High Throughput Polyvinylidene Fluoride (PVDF) Membrane-Based Proteomic Sample Preparation for 96-Well Plates[S] by Berger, Sebastian T., Ahmed, Saima, Muntel, Jan, Cuevas Polo, Nerea, Bachur, Richard, Kentsis, Alex, Steen, Judith, Steen, Hanno

“…We describe a 96-well plate compatible membrane-based proteomic sample processing method, which enables the complete processing of 96 samples (or multiples…”
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