Search Results - "Munt, Alexandra"
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Long-term dietary nitrate supplementation does not reduce renal cyst growth in experimental autosomal dominant polycystic kidney disease
Published in PloS one (22-04-2021)“…Augmentation of endogenous nitric oxide (NO) synthesis, either by the classical L-arginine-NO synthase pathway, or the recently discovered entero-salivary…”
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Efficacy of beetroot juice on reducing blood pressure in hypertensive adults with autosomal dominant polycystic kidney disease (BEET-PKD): study protocol for a double-blind, randomised, placebo-controlled trial
Published in Current controlled trials in cardiovascular medicine (29-07-2023)“…In autosomal dominant polycystic kidney disease (ADPKD) impaired nitric oxide (NO) synthesis, in part, contributes to early-onset hypertension. Beetroot juice…”
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Effect of Early and Delayed Commencement of Paricalcitol in Combination with Enalapril on the Progression of Experimental Polycystic Kidney Disease
Published in Journal of cardiovascular development and disease (29-10-2021)“…Vitamin D secosteroids are intranuclear regulators of cellular growth and suppress the renin-angiotensin system. The aim of this study was to test the…”
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Assessment of Dietary Sodium Intake Using the Scored Salt Questionnaire in Autosomal Dominant Polycystic Kidney Disease
Published in Nutrients (02-11-2020)“…The excess intake of dietary sodium is a key modifiable factor for reducing disease progression in autosomal dominant polycystic kidney disease (ADPKD). The…”
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Up-Regulation of DNA Damage Response Signaling in Autosomal Dominant Polycystic Kidney Disease
Published in The American journal of pathology (01-05-2021)“…DNA damage and alterations in DNA damage response (DDR) signaling could be one of the molecular mechanisms mediating focal kidney cyst formation in autosomal…”
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Prescribed Water Intake in Autosomal Dominant Polycystic Kidney Disease: PO2537
Published in Journal of the American Society of Nephrology (01-10-2021)Get full text
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Clinical characteristics and outcomes of hyponatraemia associated with oral water intake in adults: a systematic review
Published in BMJ open (09-12-2021)“…IntroductionExcessive water intake is rarely associated with life-threatening hyponatraemia. The aim of this study was to determine the clinical…”
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The role of DNA damage as a therapeutic target in autosomal dominant polycystic kidney disease
Published in Expert reviews in molecular medicine (26-11-2019)“…Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic kidney disease and is caused by heterozygous germ-line mutations in either…”
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Regression of Peritubular Capillaries Coincides with Angiogenesis and Renal Cyst Growth in Experimental Polycystic Kidney Disease
Published in International journal of nephrology and renovascular disease (01-01-2020)“…The natural history of the renal microvasculature changes in PKD is not known. The aim of this study was to test the hypothesis that angiogenesis is coupled…”
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Prescribed Water Intake in Autosomal Dominant Polycystic Kidney Disease
Published in NEJM evidence (01-01-2022)“…Prescribed Water Intake in Autosomal Dominant Polycystic Kidney Disease The effect of increased water intake on kidney cyst growth in patients with polycystic…”
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