Search Results - "Munt, Alexandra"

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    Long-term dietary nitrate supplementation does not reduce renal cyst growth in experimental autosomal dominant polycystic kidney disease by Zhang, Jennifer Q J, Saravanabavan, Sayanthooran, Cheng, Kai Man, Raghubanshi, Aarya, Chandra, Ashley N, Munt, Alexandra, Rayner, Benjamin, Zhang, Yunjia, Chau, Katrina, Wong, Annette T Y, Rangan, Gopala K

    Published in PloS one (22-04-2021)
    “…Augmentation of endogenous nitric oxide (NO) synthesis, either by the classical L-arginine-NO synthase pathway, or the recently discovered entero-salivary…”
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    Journal Article
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    Effect of Early and Delayed Commencement of Paricalcitol in Combination with Enalapril on the Progression of Experimental Polycystic Kidney Disease by Sagar, Priyanka S., Saravanabavan, Sayanthooran, Munt, Alexandra, Wong, Annette T. Y., Rangan, Gopala K.

    “…Vitamin D secosteroids are intranuclear regulators of cellular growth and suppress the renin-angiotensin system. The aim of this study was to test the…”
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    Up-Regulation of DNA Damage Response Signaling in Autosomal Dominant Polycystic Kidney Disease by Zhang, Jennifer Q.J., Saravanabavan, Sayanthooran, Chandra, Ashley N., Munt, Alexandra, Wong, Annette T.Y., Harris, Peter C., Harris, David C.H., McKenzie, Paul, Wang, Yiping, Rangan, Gopala K.

    Published in The American journal of pathology (01-05-2021)
    “…DNA damage and alterations in DNA damage response (DDR) signaling could be one of the molecular mechanisms mediating focal kidney cyst formation in autosomal…”
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    The role of DNA damage as a therapeutic target in autosomal dominant polycystic kidney disease by Zhang, Jennifer Q J, Saravanabavan, Sayanthooran, Munt, Alexandra, Wong, Annette T Y, Harris, David C, Harris, Peter C, Wang, Yiping, Rangan, Gopala K

    Published in Expert reviews in molecular medicine (26-11-2019)
    “…Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic kidney disease and is caused by heterozygous germ-line mutations in either…”
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    Regression of Peritubular Capillaries Coincides with Angiogenesis and Renal Cyst Growth in Experimental Polycystic Kidney Disease by O'Brien, Kristal, Saravanabavan, Sayanthooran, Zhang, Jennifer Q J, Wong, Annette T Y, Munt, Alexandra, Burgess, Jane S, Rangan, Gopala K

    “…The natural history of the renal microvasculature changes in PKD is not known. The aim of this study was to test the hypothesis that angiogenesis is coupled…”
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