Search Results - "Munson, A. E."
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Comparison of mouse strains using the local lymph node assay
Published in Toxicology (Amsterdam) (05-05-2000)“…The local lymph node assay (LLNA), as recommended by the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM), only allows for…”
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Respiratory Exposure to Diesel Exhaust Particles Decreases the Spleen IgM Response to a T Cell-Dependent Antigen in Female B6C3F1 Mice
Published in Toxicological sciences (01-02-2003)“…We investigated the systemic immunotoxic potential of respiratory exposure to diesel exhaust particles (DEP) in this study. Female B6C3F1 mice (∼8 weeks old)…”
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Evaluation of the Contact and Respiratory Sensitization Potential of Volatile Organic Compounds Generated by Simulated Indoor Air Chemistry
Published in Toxicological sciences (01-06-2007)“…Up to 60 million people working indoors experience symptoms such as eye, nose and throat irritation, headache, and fatigue. Investigations into these…”
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Immunological responses of mice following administration of natural rubber latex proteins by different routes of exposure
Published in Toxicological sciences (01-06-2000)“…Although the prevalence of IgE-mediated latex allergy has increased over the past decade, the circumstances which culminate in sensitization remain uncertain…”
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Thalidomide Stimulates Splenic IgM Antibody Response and Cytotoxic T Lymphocyte Activity and Alters Leukocyte Subpopulation Numbers in Female B6C3F1 Mice
Published in Toxicology and applied pharmacology (15-06-2000)“…Thalidomide has been shown to have antiinflammatory and, more recently, immunomodulating properties, which are beneficial for the treatment of an…”
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Gallium arsenide selectively inhibits T cell proliferation and alters expression of CD25 (IL-2R/p55)
Published in The Journal of pharmacology and experimental therapeutics (01-04-1993)“…Exposure (24 hr) to a single intratracheal administration of gallium arsenide (GaAs; 200 mg/kg) has been shown to suppress antibody production as well as other…”
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Carbon tetrachloride is immunosuppressive and decreases host resistance to Listeria monocytogenes and Streptococcus pneumoniae in female B6C3F1 mice
Published in Toxicology (Amsterdam) (23-11-2000)“…Carbon tetrachloride (CCl 4) is an environmental contaminant that has been detected in ambient air, seawater, surface-water and snow. The immunotoxic potential…”
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Evidence for arsenic as the immunosuppressive component of gallium arsenide
Published in Toxicology and applied pharmacology (01-08-1991)“…Gallium arsenide (GaAs) has been shown previously to suppress the in vivo antibody-forming cell (AFC) response to sheep erythrocytes (SRBC) when administered…”
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Splenic cell targets in gallium arsenide-induced suppression of the primary antibody response
Published in Toxicology and applied pharmacology (01-08-1991)“…In vivo exposure of female B6C3F1 mice to gallium arsenide (GaAs) was evaluated for its effect on the in vitro IgM antibody-forming cell (AFC) response. In…”
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GLYCIDOL MODULATION OF THE IMMUNE RESPONSES IN FEMALE B6C3F1 MICE
Published in Drug and chemical toxicology (New York, N.Y. 1978) (01-01-2000)“…The immunotoxic potential of glycidol was evaluated in female B6C3F1 mice using a battery of functional assays and three host resistance models. Glycidol was…”
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Qualitative and quantitative experimental models to aid in risk assessment for immunotoxicology
Published in Toxicology letters (01-12-1992)“…We have previously reported on the design and content of a screening battery using a "tier" approach for detecting potential immunosuppressive compounds in…”
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Gallium arsenide-induced increase in serum corticosterone is not responsible for suppression of the IgM antibody response
Published in The Journal of pharmacology and experimental therapeutics (01-02-1994)“…Previous investigations demonstrated gallium arsenide (GaAs) to be an immunosuppressive agent that alters the function of all cell types involved in the…”
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Hepatic and splenic phagocytosis in female B6C3F1 mice implanted with morphine sulfate pellets
Published in The Journal of pharmacology and experimental therapeutics (01-10-1993)“…Morphine sulfate has previously been shown to produce a dose-dependent decrease in hepatic phagocytosis when administered as 8-, 25- and 75-mg pellets…”
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Beta adrenoceptor mediation of the enhancing effect of norepinephrine on the murine primary antibody response in vitro
Published in The Journal of pharmacology and experimental therapeutics (01-07-1984)“…The beta adrenoceptor has been identified in this study to be the receptor responsible for the enhanced immunoglobulin M antibody response produced by…”
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Norepinephrine and the antibody response
Published in Pharmacological reviews (01-09-1985)Get more information
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Reversal of gallium arsenide-induced suppression of the antibody-forming cell response by vehicle supernatants. II. Nature and identification of reversing factors
Published in The Journal of pharmacology and experimental therapeutics (01-04-1993)“…Previous studies have demonstrated that several immunological events which are T cell mediated are significantly suppressed by a single exposure to gallium…”
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Reversal of gallium arsenide-induced suppression of the antibody-forming cell response by vehicle supernatants. I. Pharmacokinetics after in vitro and in vivo exposure
Published in The Journal of pharmacology and experimental therapeutics (01-04-1993)“…Exposure of splenocytes in vivo or in vitro to gallium arsenide (GaAs) dose-dependently suppresses the ability of these cells to produce antibody after in…”
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Octamethylcyclotetrasiloxane exhibits estrogenic activity in mice via ERα
Published in Toxicology and applied pharmacology (01-11-2003)“…Octamethylcyclotetrasiloxane (D4) is a low molecular weight cyclic silicone used in the synthesis of larger silicone polymers and in the formulation of a…”
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OXYMETHOLONE MODULATES CELL-MEDIATED IMMUNITY IN MALE B6C3F1 MICE
Published in Drug and chemical toxicology (New York, N.Y. 1978) (01-01-2000)“…Oxymetholone is a synthetic androgen, structurally related to testosterone. It is currently used to treat anemias, but has also been abused as a performance…”
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Reversal of gallium arsenide-induced suppression of the antibody response by a mixed disulfide metabolite of meso-2,3-dimercaptosuccinic acid
Published in The Journal of pharmacology and experimental therapeutics (01-02-1993)“…Meso-2,3-dimercaptosuccinic acid (DMSA) has been demonstrated to be an effective chelator of lead, mercury and arsenic in humans and in rodent experiments…”
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