Search Results - "Munro, Cynthia"

Prevalence of HIV-associated neurocognitive disorders in the Multicenter AIDS Cohort Study by Sacktor, Ned, Skolasky, Richard L, Seaberg, Eric, Munro, Cynthia, Becker, James T, Martin, Eileen, Ragin, Ann, Levine, Andrew, Miller, Eric

“…OBJECTIVE:To evaluate the frequency of HIV-associated neurocognitive disorder (HAND) in HIV+ individuals and determine whether the frequency of HAND changed…”
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Systematic Review of Neuroimaging Correlates of Executive Functioning: Converging Evidence From Different Clinical Populations by Nowrangi, Milap A, Lyketsos, Constantine, Rao, Vani, Munro, Cynthia A

“…Executive functioning (EF) is an important cognitive domain that is negatively affected in a number of neuropsychiatric conditions. The authors found that the…”
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Neuroinflammation and brain atrophy in former NFL players: An in vivo multimodal imaging pilot study by Coughlin, Jennifer M, Wang, Yuchuan, Munro, Cynthia A, Ma, Shuangchao, Yue, Chen, Chen, Shaojie, Airan, Raag, Kim, Pearl K, Adams, Ashley V, Garcia, Cinthya, Higgs, Cecilia, Sair, Haris I, Sawa, Akira, Smith, Gwenn, Lyketsos, Constantine G, Caffo, Brian, Kassiou, Michael, Guilarte, Tomas R, Pomper, Martin G

“…Abstract There are growing concerns about potential delayed, neuropsychiatric consequences (e.g, cognitive decline, mood or anxiety disorders) of…”
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Imaging of Glial Cell Activation and White Matter Integrity in Brains of Active and Recently Retired National Football League Players by Coughlin, Jennifer M, Wang, Yuchuan, Minn, Il, Bienko, Nicholas, Ambinder, Emily B, Xu, Xin, Peters, Matthew E, Dougherty, John W, Vranesic, Melin, Koo, Soo Min, Ahn, Hye-Hyun, Lee, Merton, Cottrell, Chris, Sair, Haris I, Sawa, Akira, Munro, Cynthia A, Nowinski, Christopher J, Dannals, Robert F, Lyketsos, Constantine G, Kassiou, Michael, Smith, Gwenn, Caffo, Brian, Mori, Susumu, Guilarte, Tomas R, Pomper, Martin G

“…Microglia, the resident immune cells of the central nervous system, play an important role in the brain's response to injury and neurodegenerative processes…”
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The concept of mild cognitive impairment: a victim of its ubiquity by Munro, Cynthia A

“…Mild cognitive impairment (MCI) is a term used to describe individuals with cognitive impairment that is not severe enough to affect daily functioning (e.g…”
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Effect of Citalopram on Agitation in Alzheimer Disease: The CitAD Randomized Clinical Trial by Porsteinsson, Anton P, Drye, Lea T, Pollock, Bruce G, Devanand, D. P, Frangakis, Constantine, Ismail, Zahinoor, Marano, Christopher, Meinert, Curtis L, Mintzer, Jacobo E, Munro, Cynthia A, Pelton, Gregory, Rabins, Peter V, Rosenberg, Paul B, Schneider, Lon S, Shade, David M, Weintraub, Daniel, Yesavage, Jerome, Lyketsos, Constantine G

“…IMPORTANCE Agitation is common, persistent, and associated with adverse consequences for patients with Alzheimer disease. Pharmacological treatment options,…”
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Molecular imaging of serotonin degeneration in mild cognitive impairment by Smith, Gwenn S, Barrett, Frederick S, Joo, Jin Hui, Nassery, Najlla, Savonenko, Alena, Sodums, Devin J, Marano, Christopher M, Munro, Cynthia A, Brandt, Jason, Kraut, Michael A, Zhou, Yun, Wong, Dean F, Workman, Clifford I

“…Abstract Neuropathological and neuroimaging studies have consistently demonstrated degeneration of monoamine systems, especially the serotonin system, in…”
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A - 189 Subjective Response to a Social Stressor in Individuals with Mild Cognitive Impairment by Shoemaker, Katherine, Bienko, Nicholas, Krafft, Lilly Adair, Kirby, Mackenzie, Clark, Phoebe A, Pierre, Mersania Jn, Horn, Samantha, Munro, Cynthia A

“…Abstract Objective Because stress is a risk factor for Alzheimer’s disease (ad), characterizing individual differences in the stress response could help…”
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A Phase II Study of Fornix Deep Brain Stimulation in Mild Alzheimer's Disease by Lozano, Andres M, Fosdick, Lisa, Chakravarty, M Mallar, Leoutsakos, Jeannie-Marie, Munro, Cynthia, Oh, Esther, Drake, Kristen E, Lyman, Christopher H, Rosenberg, Paul B, Anderson, William S, Tang-Wai, David F, Pendergrass, Jo Cara, Salloway, Stephen, Asaad, Wael F, Ponce, Francisco A, Burke, Anna, Sabbagh, Marwan, Wolk, David A, Baltuch, Gordon, Okun, Michael S, Foote, Kelly D, McAndrews, Mary Pat, Giacobbe, Peter, Targum, Steven D, Lyketsos, Constantine G, Smith, Gwenn S

“…Deep brain stimulation (DBS) is used to modulate the activity of dysfunctional brain circuits. The safety and efficacy of DBS in dementia is unknown. To assess…”
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Sex differences in Alzheimer's disease risk: are we looking at the wrong hormones? by Munro, Cynthia A

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Effects of Citalopram on Neuropsychiatric Symptoms in Alzheimer’s Dementia: Evidence From the CitAD Study by Leonpacher, Anne K., Peters, Matthew E., Drye, Lea T., Makino, Kelly M., Newell, Jeffery A., Devanand, D.P., Frangakis, Constantine, Munro, Cynthia A., Mintzer, Jacobo E., Pollock, Bruce G., Rosenberg, Paul B., Schneider, Lon S., Shade, David M., Weintraub, Daniel, Yesavage, Jerome, Lyketsos, Constantine G., Porsteinsson, Anton P.

“…Objective:Citalopram has been shown to improve agitation in patients with Alzheimer’s disease. The authors evaluated whether other neuropsychiatric symptoms…”
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Age at menopause and duration of reproductive period in association with dementia and cognitive function: a systematic review and meta-analysis by Georgakis, Marios K, Kalogirou, Eleni I, Diamantaras, Andreas-Antonios, Daskalopoulou, Stella S, Munro, Cynthia A, Lyketsos, Constantine G, Skalkidou, Alkistis, Petridou, Eleni Th., MD, MPH, PhD

“…Highlights • We investigated if indices of prolonged lifetime exposure to endogenous female sex hormones are associated with dementia and cognitive function. •…”
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Sertraline for the Treatment of Depression in Alzheimer Disease by Rosenberg, Paul B., M.D, Martin, Barbara K., Ph.D, Frangakis, Constantine, Ph.D, Mintzer, Jacobo E., M.D., M.B.A, Weintraub, Daniel, M.D, Porsteinsson, Anton P., M.D, Schneider, Lon S., M.D, Rabins, Peter V., M.D., M.P.H, Munro, Cynthia A., Ph.D, Meinert, Curtis L., Ph.D, Lyketsos, Constantine G., M.D., M.H.S, Drye, Lea T., Ph.D

“…Objective Depression is common in Alzheimer disease (AD), and antidepressants are commonly used for its treatment, however, evidence for antidepressant…”
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Midlife adiposity predicts cognitive decline in the prospective Multicenter AIDS Cohort Study by Rubin, Leah H, Gustafson, Deborah, Hawkins, Kellie L, Zhang, Long, Jacobson, Lisa P, Becker, James T, Munro, Cynthia A, Lake, Jordan E, Martin, Eileen, Levine, Andrew, Brown, Todd T, Sacktor, Ned, Erlandson, Kristine M

“…OBJECTIVEObesity is a common, modifiable cardiovascular and cerebrovascular risk factor. Among people with HIV, obesity may contribute to multisystem…”
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Sex Differences in Striatal Dopamine Release in Healthy Adults by Munro, Cynthia A., McCaul, Mary E., Wong, Dean F., Oswald, Lynn M., Zhou, Yun, Brasic, James, Kuwabara, Hiroto, Kumar, Anil, Alexander, Mohab, Ye, Weiguo, Wand, Gary S.

“…Sex differences in addictive disorders have been described. Preclinical studies have implicated the striatal dopamine system in these differences, but human…”
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Altered Angular Gyrus Resting State Functional Connectivity Associated with Financial Capacity in Mild Cognitive Impairment by Nowrangi, Milap A, Outen, John D, Naaz, Farah, Chen, Liuyi, Bakker, Arnold, Munro, Cynthia A, Kamath, Vidyulata, Rebok, George W, Rosenberg, Paul B

“…Financial capacity (FC) is a complex ability commonly impaired in older individuals with cognitive impairment; however, the underlying neural mechanisms are…”
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Cross-sectional analysis of cognitive function using multivariate normative comparisons in men with HIV disease by Wang, Zheng, Molsberry, Samantha A, Cheng, Yu, Kingsley, Lawrence, Levine, Andrew J, Martin, Eileen, Munro, Cynthia A, Ragin, Ann, Rubin, Leah H, Sacktor, Ned, Seaberg, Eric C, Becker, James T

“…BACKGROUND:Prevalence estimates of cognitive impairment in HIV disease vary widely. Here we used multivariate normative comparison (MNC) with identify…”
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HIV disease and diabetes interact to affect brain white matter hyperintensities and cognition by Wu, Minjie, Fatukasi, Omalara, Yang, Shaolin, Alger, Jeffery, Barker, Peter B, Hetherington, Hoby, Kim, Tae, Levine, Andrew, Martin, Eileen, Munro, Cynthia A, Parrish, Todd, Ragin, Ann, Sacktor, Ned, Seaberg, Eric, Becker, James T

“…BACKGROUND:Since the onset of combination antiretroviral therapy use, the incidence of HIV-associated dementia and of HIV encephalitis has fallen dramatically…”
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Escitalopram for agitation in Alzheimer's disease (S-CitAD): Methods and design of an investigator-initiated, randomized, controlled, multicenter clinical trial by Ehrhardt, Stephan, Porsteinsson, Anton P., Munro, Cynthia A., Rosenberg, Paul B., Pollock, Bruce G., Devanand, Davangere P., Mintzer, Jacobo, Rajji, Tarek K., Ismail, Zahinoor, Schneider, Lon S., Baksh, Sheriza N., Drye, Lea T., Avramopoulos, Dimitri, Shade, David M., Lyketsos, Constantine G., Lyketsos, Constantine G., Porsteinsson, Anton P., Avramopoulos, Dimitri, Munro, Cynthia, Lee, Hochang, Bienko, Nicholas, Shade, Dave, Ehrhardt, Stephan, Jones, Jennifer, Casper, Anne Shanklin, Frangakis, Constantine, Lears, Andy, Baksh, Sheriza, Perin, Jamie, Ryan, Laurie, McKelvy, Alvin D., Rosenberg, Paul, Nowrangi, Milap, Lawrence, Sarah, Schultz, Meghan, Jamil, Nimra, Devanand, D.P., Simon-Pearson, Laura, Pelton Jacobo Mintzer, Gregory, Brawman-Mintzer, Olga, Williams, Arthur, Awkar, Anthony, Keltz, Melanie, Kowalski, Nancy, Lane, Kaitlyn, Martin, Kim, Salem-Spencer, Susan, Widman, Asa, Pollock, Bruce G., Kumar, Sanjeev, Lourenco, Lillian, Mulsant, Benoit H., Lago, Kyle, Rajji, Tarek K., Schneider, Lon S., Becerra, Maurcio, Dagerman, Karen, Pawluczyk, Sonia, Teodoro, Liberty

“…Alzheimer's disease (AD) is a disabling, common cause of dementia, and agitation is one of the most common and distressing symptoms for patients with AD…”
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Deep Brain Stimulation Targeting the Fornix for Mild Alzheimer Dementia (the ADvance Trial): A Two Year Follow-up Including Results of Delayed Activation by Leoutsakos, Jeannie-Marie S, Yan, Haijuan, Anderson, William S, Asaad, Wael F, Baltuch, Gordon, Burke, Anna, Chakravarty, M Mallar, Drake, Kristen E, Foote, Kelly D, Fosdick, Lisa, Giacobbe, Peter, Mari, Zoltan, McAndrews, Mary Pat, Munro, Cynthia A, Oh, Esther S, Okun, Michael S, Pendergrass, Jo Cara, Ponce, Francisco A, Rosenberg, Paul B, Sabbagh, Marwan N, Salloway, Stephen, Tang-Wai, David F, Targum, Steven D, Wolk, David, Lozano, Andres M, Smith, Gwenn S, Lyketsos, Constantine G

“…Given recent challenges in developing new treatments for Alzheimer dementia (AD), it is vital to explore alternate treatment targets, such as neuromodulation…”
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