Search Results - "Munro, A."
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Fungal cell wall: An underexploited target for antifungal therapies
Published in PLoS pathogens (01-04-2021)“…A number of transcription factors are then activated including Cas5 and Rlm1 that switch on the expression of genes involved in cell wall construction and…”
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2
Reanalysis of a μ opioid receptor crystal structure reveals a covalent adduct with BU72
Published in BMC biology (10-10-2023)“…Abstract Background The first crystal structure of the active μ opioid receptor (μOR) exhibited several unexplained features. The ligand BU72 exhibited many…”
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3
The Fungal Cell Wall: Structure, Biosynthesis, and Function
Published in Microbiology spectrum (19-05-2017)“…The molecular composition of the cell wall is critical for the biology and ecology of each fungal species. Fungal walls are composed of matrix components that…”
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4
What is a virtual multidisciplinary team (vMDT)?
Published in British journal of cancer (25-06-2013)“…Background: Multidisciplinary team meetings (MDTs), also known as tumour boards or multidisciplinary case conferences, are an integral component of…”
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5
The Origins and Functions of Tissue-Resident Macrophages in Kidney Development
Published in Frontiers in physiology (25-10-2017)“…The adult kidney hosts tissue-resident macrophages that can cause, prevent, and/or repair renal damage. Most of these macrophages derive from embryonic…”
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Nutrient metal sequestration by calprotectin inhibits bacterial superoxide defense, enhancing neutrophil killing of Staphylococcus aureus
Published in Cell host & microbe (18-08-2011)“…By sequestering manganese and zinc, the neutrophil protein calprotectin plays a crucial role in host defense against bacterial and fungal pathogens. However,…”
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7
P53 abnormalities and outcomes in colorectal cancer: a systematic review
Published in British journal of cancer (14-02-2005)“…We performed a systematic review of studies that investigated the effect of abnormalities of the tumour suppressor gene p53 upon prognosis in patients with…”
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Fungal Cell Wall Proteins and Signaling Pathways Form a Cytoprotective Network to Combat Stresses
Published in Journal of fungi (Basel) (08-09-2021)“…Candida species are part of the normal flora of humans, but once the immune system of the host is impaired and they escape from commensal niches, they shift…”
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Elevated Chitin Content Reduces the Susceptibility of Candida Species to Caspofungin
Published in Antimicrobial Agents and Chemotherapy (01-01-2013)“…OA Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The potential of respiration inhibition as a new approach to combat human fungal pathogens
Published in Current genetics (01-12-2019)“…The respiratory chain has been proposed as an attractive target for the development of new therapies to tackle human fungal pathogens. This arises from the…”
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11
Single-cell analysis identifies dynamic gene expression networks that govern B cell development and transformation
Published in Nature communications (25-11-2021)“…Integration of external signals and B-lymphoid transcription factor activities organise B cell lineage commitment through alternating cycles of proliferation…”
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12
Surgical treatment of incisional hernia
Published in British journal of surgery (01-05-2002)“…Background: Incisional hernia is a common complication of abdominal surgery and an important source of morbidity. It may be repaired using open suture, open…”
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13
Caspofungin Induced Cell Wall Changes of Candida Species Influences Macrophage Interactions
Published in Frontiers in cellular and infection microbiology (12-05-2020)“…species are known to differ in their ability to cause infection and have been shown to display varied susceptibilities to antifungal drugs. Treatment with the…”
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14
Patient adherence to tuberculosis treatment: a systematic review of qualitative research
Published in PLoS medicine (01-07-2007)“…Tuberculosis (TB) is a major contributor to the global burden of disease and has received considerable attention in recent years, particularly in low- and…”
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15
Systematic Review of Neuroimaging Correlates of Executive Functioning: Converging Evidence From Different Clinical Populations
Published in The journal of neuropsychiatry and clinical neurosciences (01-04-2014)“…Executive functioning (EF) is an important cognitive domain that is negatively affected in a number of neuropsychiatric conditions. The authors found that the…”
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16
Cycles of vascular plexus formation within the nephrogenic zone of the developing mouse kidney
Published in Scientific reports (12-06-2017)“…The renal vasculature is required for blood filtration, blood pressure regulation, and pH maintenance, as well as other specialised kidney functions. Yet,…”
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Neuroinflammation and brain atrophy in former NFL players: An in vivo multimodal imaging pilot study
Published in Neurobiology of disease (01-02-2015)“…Abstract There are growing concerns about potential delayed, neuropsychiatric consequences (e.g, cognitive decline, mood or anxiety disorders) of…”
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Stimulation of chitin synthesis rescues Candida albicans from echinocandins
Published in PLoS pathogens (04-04-2008)“…Echinocandins are a new generation of novel antifungal agent that inhibit cell wall beta(1,3)-glucan synthesis and are normally cidal for the human pathogen…”
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Chitin and glucan, the yin and yang of the fungal cell wall, implications for antifungal drug discovery and therapy
Published in Advances in applied microbiology (2013)“…The structural carbohydrate polymers glucan and chitin compliment and reinforce each other in a dynamic process to maintain the integrity and physical strength…”
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Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1
Published in PLoS pathogens (01-04-2013)“…The β-glucan receptor Dectin-1 is a member of the C-type lectin family and functions as an innate pattern recognition receptor in antifungal immunity. In both…”
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