Search Results - "Munoz Pinto, Mário F."
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Gut-first Parkinson's disease is encoded by gut dysbiome
Published in Molecular neurodegeneration (24-10-2024)“…In Parkinson's patients, intestinal dysbiosis can occur years before clinical diagnosis, implicating the gut and its microbiota in the disease. Recent evidence…”
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Selective blood-brain barrier permeabilization of brain metastases by a type 1 receptor-selective tumor necrosis factor mutein
Published in Neuro-oncology (Charlottesville, Va.) (05-01-2022)“…Abstract Background Metastasis to the brain is a major challenge with poor prognosis. The blood-brain barrier (BBB) is a significant impediment to effective…”
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The neuromicrobiology of Parkinson’s disease: A unifying theory
Published in Ageing research reviews (01-09-2021)“…•Parkinson’s disease (PD) is a common progressive neurodegenerative disease with many potential aetiologies.•Bacteria are the new players involved in PD onset…”
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Footprints of a microbial toxin from the gut microbiome to mesencephalic mitochondria
Published in Gut (01-01-2023)“…Idiopathic Parkinson's disease (PD) is characterised by alpha-synuclein (aSyn) aggregation and death of dopaminergic neurons in the midbrain. Recent evidence…”
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Irisin enhances longevity by boosting SIRT1, AMPK, autophagy and telomerase
Published in Expert reviews in molecular medicine (12-12-2022)“…Ageing is characterised by the accumulation of molecular and cellular damage through time, leading to a decline in physical and mental abilities. Currently,…”
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The role of mitochondria in Gut-Brain axis in Parkinson´s disease
Published in Biochimica et biophysica acta. Molecular basis of disease (01-12-2024)Get full text
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