Search Results - "Munoz, Irene Guijarro"

Bevacizumab beyond disease progression for advanced non–small cell lung cancer: Does persistence have its rewards? by Guijarro‐Muñoz, Irene, Roarty, Emily B., Heymach, John V.

“…Persistence pays off when it comes to the vascular endothelial growth factor inhibitor bevacizumab in non–small cell lung cancer patients who have progressed…”
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Antibody gene therapy: getting closer to clinical application? by Guijarro-Muñoz, Irene, Compte, Marta, Alvarez-Vallina, Luis, Sanz, Laura

“…Monoclonal antibodies are successfully used in the clinic. However, repeated high-dose bolus injections imply high costs. As an alternative to recombinant…”
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Lipopolysaccharide activates Toll-like receptor 4 (TLR4)-mediated NF-κB signaling pathway and proinflammatory response in human pericytes by Guijarro-Muñoz, Irene, Compte, Marta, Álvarez-Cienfuegos, Ana, Álvarez-Vallina, Luis, Sanz, Laura

“…Pericytes and mesenchymal stem cells (MSCs) are ontogenically related, and in fact, no significant phenotypic differences could be observed by flow cytometry…”
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Characterization of the Immune Landscape of EGFR-Mutant NSCLC Identifies CD73/Adenosine Pathway as a Potential Therapeutic Target by Le, Xiuning, Negrao, Marcelo V, Reuben, Alexandre, Federico, Lorenzo, Diao, Lixia, McGrail, Daniel, Nilsson, Monique, Robichaux, Jacqulyne, Munoz, Irene Guijarro, Patel, Sonia, Elamin, Yasir, Fan, You-Hong, Lee, Won-Chul, Parra, Edwin, Solis Soto, Luisa Maren, Chen, Runzhe, Li, Jun, Karpinets, Tatiana, Khairullah, Roohussaba, Kadara, Humam, Behrens, Carmen, Sepesi, Boris, Wang, Ruiping, Zhu, Mingrui, Wang, Linghua, Vaporciyan, Ara, Roth, Jack, Swisher, Stephen, Haymaker, Cara, Zhang, Jianhua, Wang, Jing, Wong, Kwok-Kin, Byers, Lauren A, Bernatchez, Chantale, Zhang, Jianjun, Wistuba, Ignacio I, Gibbons, Don L, Akbay, Esra A, Heymach, John V

“…Lung adenocarcinomas harboring EGFR mutations do not respond to immune checkpoint blockade therapy and their EGFR wildtype counterpart. The mechanisms…”
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Gene expression profiling identifies EPHB4 as a potential predictive biomarker in colorectal cancer patients treated with bevacizumab by Guijarro-Muñoz, Irene, Sánchez, Antonio, Martínez-Martínez, Esther, García, Jose M., Salas, Clara, Provencio, Mariano, Álvarez-Vallina, Luis, Sanz, Laura

“…The anti-VEGF monoclonal antibody bevacizumab was approved in 2004 as a first-line treatment for metastatic colorectal cancer (CRC) in combination with…”
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Proteasome activator complex PA28 identified as an accessible target in prostate cancer by in vivo selection of human antibodies by Sánchez-Martín, David, Martínez-Torrecuadrada, Jorge, Teesalu, Tambet, Sugahara, Kazuki N., Alvarez-Cienfuegos, Ana, Ximénez-Embún, Pilar, Fernández-Periáñez, Rodrigo, Martín, M. Teresa, Molina-Privado, Irene, Ruppen-Cañás, Isabel, Blanco-Toribio, Ana, Cañamero, Marta, Cuesta, Ángel M., Compte, Marta, Kremer, Leonor, Bellas, Carmen, Alonso-Camino, Vanesa, Guijarro-Muñoz, Irene, Sanz, Laura, Ruoslahti, Erkki, Alvarez-Vallina, Luis

“…Antibody cancer therapies rely on systemically accessible targets and suitable antibodies that exert a functional activity or deliver a payload to the tumor…”
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Basement membrane-rich organoids with functional human blood vessels are permissive niches for human breast cancer metastasis by Fernández-Periáñez, Rodrigo, Molina-Privado, Irene, Rojo, Federico, Guijarro-Muñoz, Irene, Alonso-Camino, Vanesa, Zazo, Sandra, Compte, Marta, Alvarez-Cienfuegos, Ana, Cuesta, Angel M, Sánchez-Martín, David, Alvarez-Méndez, Ana M, Sanz, Laura, Alvarez-Vallina, Luis

“…Metastatic breast cancer is the leading cause of death by malignancy in women worldwide. Tumor metastasis is a multistep process encompassing local invasion of…”
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The heterotrimeric laminin coiled-coil domain exerts anti-adhesive effects and induces a pro-invasive phenotype by Santos-Valle, Patricia, Guijarro-Muñoz, Irene, Cuesta, Angel M, Alonso-Camino, Vanesa, Villate, Maider, Alvarez-Cienfuegos, Ana, Blanco, Francisco J, Sanz, Laura, Alvarez-Vallina, Luis

“…Laminins are large heterotrimeric cross-shaped extracellular matrix glycoproteins with terminal globular domains and a coiled-coil region through which the…”
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Bevacizumab beyond disease progression for advanced NSCLC: Does persistence have its rewards? by Guijarro-Munoz, Irene, Roarty, Emily B., Heymach, John V.

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Lipopolysaccharide Activates Toll-like Receptor 4 (TLR4)-mediated NF-κB Signaling Pathway and Proinflammatory Response in Human PericytesThis work was supported by Fondo de Investigaciones Sanitarias/Instituto de Salud Carlos III Grants PI08/90856 and PS09/00227 and Fundación Investigación Biomédica Hospital Puerta de Hierro (to L. S.) and by Ministerio de Economía y Competitividad Grant BIO2011-22738 and Comunidad de Madrid Grant S2010/BMD-2312 (to L. A.-V.) by Guijarro-Muñoz, Irene, Compte, Marta, Álvarez-Cienfuegos, Ana, Álvarez-Vallina, Luis, Sanz, Laura

“…Pericytes and mesenchymal stem cells (MSCs) are ontogenically related, and in fact, no significant phenotypic differences could be observed by flow cytometry…”
Get full text